Ribose Puns

Can’t find them in the spec

I bought D-Ribose and started a little to test in a shake and it gave me instant heartburn. Tried again with water and it did the same thing.

Later I tried it with food and I didn't do much. But a few days later I started getting abdominal cramps. Now a week later I still have it and I haven't touched the stuff for days.

Long shot probably but did anyone else get a bad response from d-ribose?

I know fructose and ribose are the most easily identifiable since the latter has 5 carbons and the former is a 5-membered ring, but glucose, mannose, and galactose never seem to stick for me. Anyone have any tips/memory devices?

Obviously, deoxyribose is part of DNA and ribose is part of RNA, but I'm sure there are more monosaccharides with this ability. Reading some articles, I found that synthetic nucleic acids have been created using threose (a tetrose) or arabinose (a pentose like ribose), or even non-monosaccharides like glycol or cyclohexane. Knowing that many different substances can be used to make these nucleic acids, what are the limitations? If some pentoses and a tetrose can be used, then can a hexose or triose? All of the sugars previously mentioned were aldoses, but can nucleic acids be made from ketoses too?

Will ribose affect the "willingness" of the body to go into ketosis? Should it not matter? Ribose is a product of the pentose phosphate pathway (PPP) which is how red blood cells, lacking mitochondria, provide energy for themselves. The PPP is not downregulated in ketosis, right? If it were, ketosis would cause hemolysis. The gluconeogenesis that does occur is especially for these solely glycolytic processes, right? So increasing ribose would reduce gluconeogenesis, theoretically.

Any anecdotes using this sup?

Searching to find something to give me more energy. Please don't start with diet, sleep, excercise, meditation, breathing. Long ago have learned what are the cornerstones. Need some additional fuel. Tried some stuff but can't say I felt much. Now taking niacin 2x500mg for NAD+. 52y/m with lots of stress.

How can I make it last.

Does anyone know how D-Ribose affects gut microbiome? Thanks.

Hi, guys! I've already asked this question on the keto science sub, but nobody answered.

1. Does glycine affect ketosis in some way? Specifically, does it kick you out of ketosis? My guess is that it is keto-friendly, bcos is just an amino acid - but better to be sure. I am taking it for medical reasons to improve my sleep.

2. I had a conversation with a fellow ketoer and we discussed if I should track it; because well, ribose is a simple sugar/carb. I take it, again, for medical reasons - 5-10 grams a day. On the back of the package, the nutritional info states 'Carbs: N/A'. The powder is from Bulk Powders.

So I'm quite confused. Should I track it or not? My friend believes it should definitely be tracked because it's pure sugar/carbs, and that the nutritional info is completely incorrect.

Thanks!

I pray to God that I get back to my baseline soon.

I have found that D-Ribose is very helpful for me but my friend with fibro said it did nothing for her. So.... YMMV

Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c03552

Luca Legnani, Andrea Darù, Alexander X. Jones, and Donna G. Blackmond

https://ift.tt/33BIGJ5

Sorry if sounds too naive, can i get the same benefits as NR itself?

Has anyone had any positive effects with these sups ? Or should I not even bother

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c12246

Morgan Dasovich, Morgan Q. Beckett, Scott Bailey, Shao-En Ong, Marc M. Greenberg, and Anthony K. L. Leung

https://ift.tt/3be9pP7

I have severe CFS, bedbound and in pain and discomfort every day. I’ve been this way since July, after I wayyy over did it on a hike. I was completely healthy and didn’t have CFS before that, aside from not having been feeling well for a few months because of an accidental corticosteroid overdose In May. So my thing with CFS seems to be an energy problem (not a viral problem, etc). It greatly improves with sleep, but after a while things kept getting worse because being bed bound made it incredibly easy to overexert myself, and good sleep became impossible.

About a month ago, I started taking D Ribose and it helped immediately. In the morning, I was feeling my disease spiral out of control, started having a meltdown, and by the afternoon, I just stopped crying and started feeling actually tired and relaxed, and that night I felt good and hopeful, and I actually got great sleep. After just a few days my whole situation was different, I was able to sit in a chair all day and play video games, and then get back in bed at night. It was a miracle. And the craziest part, my symptoms were improving every single day. Every day that I didn’t push myself, I felt better, and I could get in bed later, and my sleep was solid. But I was stupid and overdid it. I spent 3 hours having my hair detangled and cut and it was too much. And now I’m not in that good place anymore.

But something weird is happening. The D Ribose is working miraculously, but only like once every 5-8 days or so. It will work enough to get me some sleep and to feel immensely better for a couple days, but it doesn’t work quite enough in that one day to bring me out of this hole, so I relapse again before the next time it works again. So my question is why doesn’t it work more often? It worked more often when I was a little healthier. So I must be depleting something else, but I don’t know what. CoEnzyme Q10? NR? I have been taking ubiquinol 100-200mg for about 2 weeks, but I’m not sure if that’s it.

I am desperate for answer. It seems like I’ve found my cure, but only 50% of it. Please help if you have any ideas. TIA

Hi all. I have mild CFS which I was diagnosed with a few years ago. D-Ribose was one of the only things I found that gave me a significant boost in energy. I was taking 5g 3 times a day for 2 years until someone on here posted a possible link to dementia so I stopped taking it.

I started taking 1000mg of magnesium malate 3 times a day which helped but gave me nowhere near as much energy.

I have been having less and less energy recently so I am thinking of starting on D-Ribose again.

How does everyone else feel about D-Ribose, have you been taking it for long periods of time?

Thanks for any advice.

So I'm sick of being this way, so am actively going to try new different things to see if anything helps. I saw some people reported success with D-Ribose.

I've taken 5g for a week solid and have noticed absolutely no difference. Is it too early to tell at this stage, should I have more, what's everyone elses experience?

Anyone had any success with alleviating symptoms from this?

Just stumbled upon this article: https://pubmed.ncbi.nlm.nih.gov/26452037/

Any opinions?

Hi, guys! I thought this might be the best place to ask these questions:

1. Does glycine affect ketosis in some way? Specifically, does it kick you out of ketosis? I am taking it for medical reasons to improve my sleep.

2. I had a conversation with a fellow ketoer and we discussed if I should track D-ribose as a carb, because is a simple sugar. I take it again, for medical reasons, 10 grams a day. On the back of the package, the nutritional info states 'Carbs: N/A'. The powder is from Bulk Powders. So I'm quite confused. Should I track it or not? My friend believes it should definitely be tracked and that the nutritional info is completely incorrect.

Thanks!