Predictions of the SARS-CoV-2 Omicron Variant (B.1.1.529) Spike Protein Receptor-Binding Domain Structure and Neutralizing Antibody Interactions biorxiv.org/content/10.11โ€ฆ
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๐Ÿ‘ค︎ u/afk05
๐Ÿ“…︎ Dec 07 2021
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LNC RNA -Protein interaction

I am looking for tools to predict the LNC RNA -Protein interaction,what are some of the reliable tools in which I can enter my Lnc RNA and Protein sequence and the software predicts the possible interaction between the two?

I m looking for 3-4 softwares to obtain a consensus result..

Are there any alternative and more accurate ways to predict the interaction of Lnc RNA and Protein?

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๐Ÿ‘ค︎ u/Chilli___
๐Ÿ“…︎ Jan 24 2022
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Research identifies sildenafil as candidate drug for Alzheimerโ€™s disease. Scientists examined the impact of over 1,600 FDA-approved drugs on the various proteins involved with AD, and found that sildenafil was the most effective at disrupting the interaction between amyloid and tau proteins. eurekalert.org/news-releaโ€ฆ
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๐Ÿ‘ค︎ u/Wagamaga
๐Ÿ“…︎ Dec 07 2021
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Comparative analysis of protein-protein interaction networks in metastatic breast cancer journals.plos.org/plosoneโ€ฆ
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๐Ÿ“…︎ Jan 21 2022
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Predictions of the SARS-CoV-2 Omicron Variant (B.1.1.529) Spike Protein Receptor-Binding Domain Structure and Neutralizing Antibody Interactions biorxiv.org/content/10.11โ€ฆ
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๐Ÿ‘ค︎ u/BillMurray2022
๐Ÿ“…︎ Dec 07 2021
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Comparative analysis of protein-protein interaction networks in metastatic breast cancer. Another indication on the CCR5 pathway - CYTODYN journals.plos.org/plosoneโ€ฆ
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๐Ÿ“…︎ Jan 21 2022
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Artificial intelligence successfully predicts protein interactions - Research led by UT Southwestern and the University of Washington could lead to a wealth of drug targets utsouthwestern.edu/newsroโ€ฆ
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๐Ÿ‘ค︎ u/Dr_Singularity
๐Ÿ“…︎ Nov 22 2021
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Protein-ligand interactions

Competetive binding experiments and saturation experiments are both examples of equilibrium binding assays. Are there specific cases where you would choose one over the other?

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๐Ÿ‘ค︎ u/Local-Ad1317
๐Ÿ“…︎ Jan 17 2022
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Comparative analysis of protein-protein interaction networks in metastatic breast cancer journals.plos.org/plosoneโ€ฆ
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๐Ÿ“…︎ Jan 21 2022
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Interactions between SARS-CoV-2 N-Protein and ฮฑ-Synuclein Accelerate Amyloid Formation pubs.acs.org/doi/10.1021/โ€ฆ
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๐Ÿ‘ค︎ u/afk05
๐Ÿ“…︎ Dec 22 2021
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Interactions between SARS-CoV-2 N-Protein and ฮฑ-Synuclein Accelerate Amyloid Formation pubs.acs.org/doi/10.1021/โ€ฆ
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๐Ÿ‘ค︎ u/afk05
๐Ÿ“…︎ Dec 22 2021
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RNA-protein interaction prediction help

Hey, Im looking into the prediction of interaction between a RNA binding protein and a custom sets of RNA. Does anyone know a good web server or a paper that can help me with that? I want to predict if they will bind to eachother and which fragments of the sequences will be involved in that process. That second part is important because there is experimentary data showing that my protein binds to the stem loops of the mRNA and I want to use that Information to check if the algorithm is consistent with it. Right now the only tool I found useful is catRAPID.

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๐Ÿ‘ค︎ u/WhyNot13134
๐Ÿ“…︎ Jan 02 2022
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Multivalent Interactions between Molecular Components Involved in Clathrin Independent Endocytosis Drive Protein Phase Separation biorxiv.org/content/10.11โ€ฆ
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๐Ÿ‘ค︎ u/sburgess86
๐Ÿ“…︎ Dec 29 2021
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New study from the Czech and American teams highlights the role of disordered protein interactions in gene expression science.org/doi/10.1126/sโ€ฆ
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๐Ÿ‘ค︎ u/mightx
๐Ÿ“…︎ Dec 06 2021
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MIT engineers design the first synthetic circuit that consists entirely of fast, reversible protein-protein interactions. news.mit.edu/2021/synthetโ€ฆ
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๐Ÿ‘ค︎ u/thebelsnickle1991
๐Ÿ“…︎ Jul 04 2021
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A first-of-its-kind study has found that cone snail venom, conotoxin from a species of sea snail, could potentially treat severe malaria, by disrupting the protein-protein interactions of P. falciparum malaria. Emerging diseases like AIDS and COVID-19 may also benefit from conotoxins as treatment. fau.edu/newsdesk/articlesโ€ฆ
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๐Ÿ‘ค︎ u/mvea
๐Ÿ“…︎ Feb 21 2021
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Alternate mechanisms of SARS-CoV-2โ€“induced analgesia and additional pathological significance of SARS-CoV-2 spike protein interaction with vascular endothelial growth factor-A/neuropilin-1 receptor signaling journals.lww.com/pain/Citโ€ฆ
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๐Ÿ‘ค︎ u/icloudbug
๐Ÿ“…︎ Dec 05 2021
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In silico evaluation of the interaction between ACE2 and SARS-CoV-2 Spike protein in a hyperglycemic environment nature.com/articles/s4159โ€ฆ
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๐Ÿ‘ค︎ u/icloudbug
๐Ÿ“…︎ Dec 05 2021
๐Ÿšจ︎ report
What is lexapro(ssri) and protein powder interaction?

before lexapro i have tried protein powder and few types gainer , but all of them gave me anxiety and since i dont know what is reason of it. all of them does not contains any dairy or coffeine or sugar

but all has amino acids, there is one l-tripthopan , which converts in serotonine.

i want to try again ,how it will affect my body and is it dangerious with lex, as alcohol or weed?

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๐Ÿ‘ค︎ u/garni1999
๐Ÿ“…︎ Nov 18 2021
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A Functional Interaction Between the SARS-CoV-2 Spike Protein and the Human ฮฑ7 Nicotinic Receptor researchsquare.com/articlโ€ฆ
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๐Ÿ‘ค︎ u/icloudbug
๐Ÿ“…︎ Oct 10 2021
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