YO on the NS FL #1, the passage that covers questions 48-52 on CP tells me that an aromatic ring with an NO2 substituent DONATES in electron density, thus stabilizing a nearby carbocation. I can't seem to wrap my head around how NO2 would/could ever donate in electron density. Here's a photo of the molecule I'm talking about:
THANKS IN ADVANCE!
What sort of directing and activating/deactivating effects would a C=C bond have when conjugated with an aromatic ring system? (ie. at the benzylic position)
In drawing resonance structures for it, I find I can either place a negative or positive charge in the ring, and so I'm not sure which really occurs.
Without drawing resonance structures, it appears to be an alkyl substituent...so therefore mildly activating and an ortho- para- director? That's what I would guess resonance aside...
But I know resonance has to have something to do with this (it's conjugated...I have a feeling it's important somehow) but not sure how...
Can anyone help?
I know they all in general slow it down. But, why? I mean because it decreaes amount of negative electron density spots on the molecule making it a shitty nucleophile?
Remarkable effects of SiMe 3 , SiEt 3 para ‐substituent in the phenoxide‐modified half‐titanocenes, Cp*TiCl 2 (O‐2,6‐ i Pr 2 ‐4‐R‐C 6 H 2 ) [R = SiMe 3 ( 6 ), SiEt 3 ( 7 )], toward the catalytic activities in ethylene copolymerizations with 2‐methyl‐1‐pentene, 1‐decene, 1‐dodecene and with 9‐decen‐1‐ol (DC‐OH) have been demonstrated. The activities by 6 , 7 at 50 ºC showed higher than those conducted at 25 ºC in all cases in the presence of MAO cocatalyst. Efficient synthesis of high molecular weight (HMW) ethylene copolymers incorporating DC‐OH (or 5‐hexen‐1‐ol, HX‐OH) has been attained in the copolymerization by 7 , which showed better DC‐OH (HX‐OH) incorporation at 50 ºC to afford the HMW copolymers, poly(ethylene‐ co ‐DC‐OH)s, with high activities (activity 1.21–3.81×10 5 kg‐polymer/mol‐Ti·h, M n = 6.55‐10.0×10 4 , DC‐OH 2.3‐3.6 mol %).
https://ift.tt/2R3pVrn
In this research, effect of electronegative F, Cl, NO2 and CF3 substituents on aromaticity of highly substituted benzene molecules is studied. NICS, ASE, HOMA and HOMO-LUMO energy gaps were the indices which are applied to show effect of substituents. In addition, sigma and pi-electron donor acceptors are calculated for all the substituted molecules. Additionally, total electron donor acceptor tEDA was proposed as a new descriptor which was the sum of two previously mentioned descriptors and show total electrons.The trend of results is different for all methods. For instance the behavior of NICS is contrariwise to ASE and HOMO-LUMO energy gaps results and HOMA index calculation provided no valuable information. As other results, it was shown that the calculated NICS in center of rings was changed not only by ring current but also altered with the presence of other atoms fields. The isomerization effect of the aromaticity also was studied and it was shown that the energy, ASE, and HOMA indices adapted to tEDA descriptors. Deficiency of NICS and HOMA methods in predicting the substituent effects illuminated in this research which the NICS deficiency is explained by the fact that the chemical shift of nucleus was resulted from two sources: ring current and other atoms presence.
Just something that's been irking me because I see it on this sub all the time. I've tried to comment about it before but it was removed for a reason I can't remember.
Noids with CN (cyanide) in the name are not inherently any more dangerous than other noids. A cyanide is any organic compound containing a cyano group, C≡N. It's literally just a carbon triple bonded to a nitrogen. When we talk about cyanide colloquially, we're referring to cyanide salts like sodium or potassium cyanide, which will kill you. However, cyano-containing cannabinoids are complex organic molecules that do not freely dissociate to form CN- ions. You'll be fine.
https://preview.redd.it/7jslgy88wm581.png?width=880&format=png&auto=webp&s=66d0d403eb60d808f65704b283afd701aab9c98d
I have an organic chem prof who says that when naming alkanes, complex substituents are alphabetized by the last "word" in the substituent (e.g. (1,1-dimethylpropyl) would be alphabetized by "p").
Furthermore, he says that if you have multiple complex substituents, you don't alphabetize them at all- you order them in the name by increasing number on the parent chain.
I've been doing a ton of research on organic chemistry tutor, ucalgary, and a few other organic tutoring sites. They all say this is NOT the way alkanes are named. Has anyone seen this method that my prof uses? Or is he just completely cracked? Am I cracked?
http://imgur.com/a/gctpkxy
Pope-purri
I'm studying organic chemistry with a student and we got to asking why the nitrates on TNT are in those specific spots. If you move the nitrate substituents to like the 2 3 6 or 2 3 5 spots does it really mess up the molecule?
Additionally, how significant of a role does the inhibition of MAO play in the increase of extracellular dopamine concentrations compared to the molecule's competitive inhibition of dopamine reuptake, or its properties as a dopamine releasing agent?
