FOAF's been diagnosed with B-cell CLL. There seem to be two variants with very different survival prospects, and the diagnostic marker between the two is ZAP70. He received back a full lab result, but NO EXPLANATION (this would be I think illegal in the US, but this friend lives in a country where doctors are culturally empowered to lie to their patients). The last few lines of the lab result say (my translation): "Normal immunophenotype B-cells are only 0.2%, the rest are pathological, CD5/CD20dim/CD22dim/CD23/CD43 positive and CD81/CD10/CD79b negative immunophenotype. Of the pathological cells 15% CD25dim and CD11c positive. No light chain expression detectable. On the normal cells the kappa/lambda ratio is 1.7. Of the abnormal cells 46% is CD38+ and 2.4% Zap70+.
So the question is: which variant of B-CLL are we talking about. Your help (including pointers to medical literature) is greatly appreciated.
Do your worst!
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂
It really does, I swear!
They’re on standbi
Pilot on me!!
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
When I got home, they were still there.
I won't be doing that today!
You take away their little brooms
This morning, my 4 year old daughter.
Daughter: I'm hungry
Me: nerves building, smile widening
Me: Hi hungry, I'm dad.
She had no idea what was going on but I finally did it.
Thank you all for listening.
There hasn't been a post all year!
Buenosdillas
It’s pronounced “Noel.”
After all his first name is No-vac
What, then, is Chinese rap?
Edit:
Notable mentions from the comments:
-
Spanish/Swedish/Swiss/Serbian hits
-
French/Finnish art
-
Country/Canadian rap
-
Chinese/Country/Canadian rock
-
Turkish/Tunisian/Taiwanese rap
There hasn't been a single post this year!
(Happy 2022 from New Zealand)
Nothing, it just waved
Bob
So that I could frequently say, "I am going to walk 5 miles now."
Edit: My most popular post on Reddit! 😀 Thank you for the awards.
Just to clarify, 12345678
Me grabbing a soda from my (what I thought was) half full 12pk...
Notices there's only 2;
Me: "Awe man... This is a damn bird box!" Her: "What the hell does that mean?!" Me: (Pulls both cans out & shows them to her) "It's only got Toucans."
I'm not ashamed to admit the look on her face was glorious.
I was just sitting there doing nothing.
“BOOM”?!
"That's what they're fighting about."
