https://preview.redd.it/vbdm0hi7tzv61.png?width=532&format=png&auto=webp&s=4f24809612c4c1d88050dea42595088983c72141

I went to the endocrinologist and found out that my prolactin and dhea levels were high. He put me bromocriptine 5mg for a month for my prolactin level and when I went for a checkup afterwards both levels went down some, but not to normal range ( I also has some great progress with my symptoms. ex: period was normal for the first time in 6 months). Now he's telling me to take 10mg daily for 3 months instead to see if my levels get back to normal. Has anyone else had this happen to them where it's just prolactin and dhea that is high? And if so has anything worked to bring them down, for example bromocriptine? Or is this just useless bc I probably have PCOS? I'm just curious if anyone is/was in the same situation as me :/.

I am in PMO addiction from 10 years so I done above mentioned tests so i found high prolactin level (35 ng/ml) and testosterone is 4.71 ng/ml. not confirmed about doppler test performed correctly or not and semen analysis is pending I will update once done. so anyone has done the test to check their hormones function is normal please suggest because I think due to prolactin I am having low libido and erectile dysfunction I am on day 40 of no fap but my libido and erection gone so I done above tests and I am confused as if my erection and testosterone level became better or not if I took treatment for prolactin reduction or I need trt. any suggestions will be helpful.

Hi all, First reddit post so forgive me if I waffle! I'm looking for a bit of advice from anyone who knows a thing or two about female hormones.

I have had PCOS for years so that's nothing new, symptoms are hair loss (yikes), acne, greasy hair/skin and fatigue. I managed to get the acne under control a couple years back with Bicalutamine 50mg daily which I ordered myself after researching its anti androgen properties (I know I know, its for prostate cancer, I dont have a prostate and I should have consulted with a doctor but thats a long story for another post but a million GP appointments, creams, pills never worked and no GP seemed really that interested in helping me) Bical worked like a DREAM and I had clear skin for the first time in years and I wasn't greasy anymore! I eventually came off the bical in 2019 and after a short "relapse" breakout all was well again. I now only take the birth control pill Yasmin due to its dual estrogen and progesterone.

I'm not anti-vac buuuuut I noticed after my booster (Pfizer) I had a massive acne flair up and crazy greasy hair and excessive hair shedding, which I presumed to mean one thing - hormones were out of whack again!

Anyway I ordered a private hormone blood test and got the results yesterday. These are my abnormal results:

SHBG >200 (normal range = 32.4 - 128) Prolactin 915 mUl (normal range 102 - 496) Testosterone 1.83 (normal 0.29 - 1.67)

I also got an advanced thyroid profile, estrogen, FH etc and I had my liver tested recently and everything there came back normal.

I've done a bit of research and I understand that high prolactin suppresses SHBG, so how can they both be high? My testosterone comes as no surprise due to the already known PCOS but now I'm thinking to go back on the Bicalutamine again... but I've also read that whilst it can decrease prolactin it can also raise SHBG so I'm hesitant, but again confused as to how they can BOTH be high if they contradict/suppress each other? I've also read PCOS usually means LOW SHBG so again I'm confused... am I missing something?

Also, any advice on sorting this hormonal mess would be much appreciated too! Should I take the plunge with my Bical again?

Thank you in advance ☺️

Long term user of Bromantane here, I always researched on this topic and couldnt really find anything other than (summarized) "Prolactin can inhibit testosterone production and has next to no good use in men" also read that it desensetizes androgen receptors and makes you sleepy. If im wrong you can gladly inform me otherwise as informations arent really findable at this moment.

Edit: My sex drive is unhuman since taking it for over a year, I can ejaculate multiple times but after 2 its dry, not wanting to brag its more of an annoyance because after 1 day I cant stop thinking about sex, any idea on how to fix this?

Prolactin also causes to put on body fat

My doctors pumped me full of ' second - generation ' anti-psychotics, that gave me bad prolactin increase, so my nipples doubled in size, in three months, on 500 mg seroquel ( also made my teeth hurt, others have lost many teeth, from it ) . .

They write 1 %, or 10 % get prolactin, but the number, acc. to medical students is 100 %, or very close . . AP's block dopamine receptors, particularly D2 dopamine receptors, when that happens, prolactin increases in most people, as dopamine is the prolactin inhibiting factor ( PIF ) . . Being on a maternal instinct hormone made me into a ' transvestite ', and the staff, nurses, and other workers, made FUN of it, but then told me, it's psychotic, it's not the pills . . Sure, being ' emotional ' is always psychotic, as ' emotions ' are ' made ' up, or ' thoughts ', I felt that way for 22 - 23 hours each day, every other thought being giving oral sex, to men, I'm normally a 98 - 99 % heterosexual, and every other thought was, how I can kill myself, made me VERY, VERY suicidal . . When I complained in court, they LIED about what they learn in medical school, see here, from medical text-books, articles . .

https://preview.redd.it/jr4mjpu3o7661.jpg?width=1116&format=pjpg&auto=webp&s=bb39d603af44731b149598d056866fa3feef101d

https://preview.redd.it/ywssh2i5o7661.jpg?width=1920&format=pjpg&auto=webp&s=38bb9ac84d41e8c690161c6be4baa86c0365c099

It felt, like this . .

https://preview.redd.it/gdqtp9e7o7661.jpg?width=863&format=pjpg&auto=webp&s=949daf3975e35ead62a29b5b786a7cf97f597e6f

And, blocking dopamine system causes head-aches, decreased cognitive function, etc etc . .

Felt, like this, almost, or close . .

https://preview.redd.it/zwfkgaibo7661.jpg?width=1652&format=pjpg&auto=webp&s=3a5741e07dde18ea3ad4e9582abf25e4a0c1a74e

Near, to migraines . .

When the judges, and lawyers asked them, is this related to the drugs, they said NO, he has delusions, about side-effects, it has NOTHING to do, with the drugs . . On these lies, I've been forced to take clozapine, for over 4 years now, against my will, aka leponex, lepo-nex, where . .

LEPO = greek, for leper, leprosy

NEX = latin, for death, violent murder

I've had to solve my own mental problems, OCD, mild autism, depression, with mindfulness, and meditation . . well, I always knew psychiatry had a reputation, for mangling patients, now I know what the current ' tools ' are . . Chemical homosexuality, which hurts lik

A little back story – Initially my first month after doing all the tests (TONS of blood work, HCG, cycle investigation process etc) I was told my fertility treatment would be put on hold until my hormones were all within range.. I was prescribed Synthroid to treat my thyroid levels that were too high and with taking this medication itself, my fertility doctor mentioned it most likely will indirectly treat my high prolactin levels too.. So they gave me the meds and told me to come back for blood work in 6 weeks from then (so the medication can take full effect) ok. Cool. Did that and had another follow up, what the doctor told me was that my thyroid levels were slowly decreasing and becoming in the right range for pregnancy but my prolactin levels had not decreased at all. So now we must treat both.   He prescribed me dostinex (cabergoline) 5mg to take once a week as well as the Synthroid daily.   The dostinex itself I haven’t been feeling any side effects shockingly, but that might be cause I ALREADY suffer from severe anxiety lol. But one thing I did notice was my period only lasted 2 full days this cycle (first cycle with dostinex) when usually it would be a full 5-7 days. Should I be worried about that? Or could it be that my body is adjusting to everything…? I don’t understand why my period would be so short, never has been.   I am just feeling very overwhelmed and discouraged with how long the process is taking to get my hormones into the right range to ACTUALLY start a treatment plan… I feel like there isn’t much I can do until then?   I’d love to hear if anyone else has had a situation like this or has been prescribed dostinex (cabergoline) for high prolactin levels for trying to conceive, if you were – what was the outcome? Was there any changes in your cycle or period length? Any advice would be appreciated, just trying to give myself a peace of mind. Next steps are to do a follow up blood test beginning of February – if my prolactin and thyroid levels are increasing as they should be, I will be starting IUI and ovulation induction next cycle (going into March). That is only if, my hormones are in the right range finally.

Only these two have inhibitors that are dopamine and GHIH (somatostatin) and I really want to know what's the explanation for this... If someone can help me I would appreciate a lot 💙 Thx

I’m a 25 year old male. Low energy, periodic limb movement sleep disorder. I always have to nap. Never have drive or energy to do anything. I wake up a lot, and I basically can't have a job because I'm so exhausted all the time. I never feel rested. My neurologist recommended I see an endocrinologist. Went in for labs today. Here they are: https://imgur.com/a/3cgYAl9

Weight 200

Height 5’10

Medications Creon 36000 for early mild chronic pancreatitis. Mostly a non issue.

Cholecystectomy 1/2019 - path lab diagnosed mild chronic cholecystitis. Ejection fraction 32 percent combined with GI symptoms prompted surgery.

I've had multiple recent thyroid labs and they have all been normal. The idea of a possible pituitary tumor is a bit scary, and I'm looking for help piecing these labs together before my appointment which is in a month.. but I'm hoping to make it sooner as it falls on my birthday.

Technically my testosterone is "normal" but multiple doctors I've seen would like that number to be higher. I appreciate any help!

This is my blood test https://imgur.com/gallery/58wqM0A And I'm really shocked from the results , prolactin almost twice as the highest range ,and T is also low for my age (18). I've fatigue , depression ,low metabolism . Sex is good . What should I do?

I understand that since Annovera lasts for a full year (compared to Nuvaring that only lasts a month) it would have more restrictions, but 2 hours vs 48 hours is a very drastic difference.

Annovera does release slightly less estrogen than Nuvaring (13mcg vs 15mcg), but it also releases more progestin (150mcg vs 120mcg), so I don’t feel like those slight variances would make that much of a difference.

Is Annovera just being overly conservative with the adherence guidelines since it’s new? Or is there really that much of a difference between the two of them, and if so, why?

EDIT:

First, when I say “can be removed for x hours/month,” I meant during the 21 day period you are supposed to have it in. I am aware you are supposed to remove it during the break week, but I am not talking about that.

Second, Many of you pointed out that on the Nuvaring website it states it cannot be removed for >3 hours, however, both Planned Parenthood and UC Berkeley state that it is still effective for up to 48 hours. So a follow-up question would be why do both Berkeley and Planned Parenthood (both reputable sources) state 48 hours as the limit?

EDIT 2: Okay I’m tired of people saying “are you sure you interpreted Planned Parenthood/Berkeley correctly?” So here is a direct quote from the Berkeley source listed above:

>> [for] delayed insertion of a new ring or delayed reinsertion of a current ring for <48 hours since a ring should have been inserted • Insert ring as soon as possible. • Keep the ring in until the scheduled ring removal day • No additional contraceptive protection is needed

And a quote from Planned Parenthood:

>> ...sometimes the NuvaRing might slip out of your vagina. If the ring has been out of your vagina for less than 2 days, rinse it in cool water and put it back in right away. If you put it back in within 48 hours, you’ll still be protected from pregnancy.

EDIT 3: CDC and WHO (see page 52) also recommend the <48hr rule

Tests were done at 8:30 AM. I used ipam/mod an hour before blood was drawn.

EDIT: IGF-1 came back at 326ng/ml https://i.imgur.com/FTVTxMa.jpg

I am taking 75 mg of test cyp twice a week. 350 iu of HCG twice a week. 100mcg of ipam three times a day and 100mcg mod grf three times a day. Sexual desire has been lower than usual and I have felt tired especially in the morning when I wake up. I had igf-1 done also but the results have not come back yet for some reason. Thanks

I noticed there are no discussions regarding GHRP and cardiovascular health.

GHRP has profound effects that people with heart failure may potentially benefit from.

I don't want to cite all the studies. Just Google "ghrp heart" and you will see some promising information.

I figured I'd bring some awareness to some.

Hi all, I am hoping to gather feedback on a theory I have regarding cortisol. The literature informs us that secretion of adrenocorticotropic hormone (ACTH) stimulates secretion of cortisol by the adrenal glands - this action is mediated by the hypothalamic-pituitary-adrenal (HPA) axis.

https://pubmed.ncbi.nlm.nih.gov/27104844/

The HPA axis is influenced by; the hypthalamus, the pituitary gland and the adrenal glands.

https://www.sciencedirect.com/topics/neuroscience/hypothalamic-pituitary-adrenal-axis

My hypothesis is that you aim to dampen the potential of hpa-axis hyperactivity and attenuate HPA dysregulaton - this accomplished by controlling ACTH release using a corticotropin releasing hormone antagonist or a drug which operates akin to a CRH. What are the opinions and thoughts on this approach?

thanks in advance

EDIT: I meant mental clarity.

Before hormone therapy I had Gynecomastia.(small..) Prolactin is said to play a role in the development of mammary gland. Now I have been hormone treatment for 5 to 6 months. Is Gynecomastia a good condition for breast growth? Thank you for reading my thread

I've recently learned a little about prolactin, a hormone that has heightened production for two weeks after orgasm. It also has an inverse relationship with dopamine.

"When a high blood prolactin concentration interferes with the function of the testicles, the production of testosterone (the main male sex hormone) and sperm decrease. Low testosterone causes decreased energy, sex drive, muscle mass and strength, and blood count."

I'm not sure if this is good or bad for people on NoFap. Will you have lower prolactin if you don't fap at all, or will it cause problems from lack of dopamine causing less testosterone production?

Any medical folks are welcome to help me understand. (this isn't about porn/addiction. More about the hormonal effects of orgasm.)

I am in PMO addiction from 10 years so I done above mentioned tests so i found high prolactin level (35 ng/ml) and testosterone is 4.71 ng/ml. not confirmed about doppler test performed correctly or not and semen analysis is pending I will update once done. so anyone has done the test to check their hormones function is normal please suggest because I think due to prolactin I am having low libido and erectile dysfunction I am on day 40 of no fap but my libido and erection gone so I done above tests and I am confused as if my erection and testosterone level became better or not if I took treatment for prolactin reduction or I need trt. any suggestions will be helpful.

I am in this addiction from 10 years so I done above mentioned tests so i found high prolactin level (35) and testosterone is 4.71. not confirmed about doppler test performed correctly or not and semen analysis is pending I will update once done. so anyone has done the test to check their hormones function is normal please suggest because I think due to prolactin I am having low libido and flatline I am on day 40 of no fap but my libido and erection gone so I done above tests. any suggestions will be helpful.

Just trying to understand my blood test reports and I don't want to take the pill as my endo prescribed 🥺

A little back story – Initially my first month after doing all the tests (TONS of blood work, HCG, cycle investigation process etc) I was told my fertility treatment would be put on hold until my hormones were all within range.. I was prescribed Synthroid to treat my thyroid levels that were too high and with taking this medication itself, my fertility doctor mentioned it most likely will indirectly treat my high prolactin levels too.. So they gave me the meds and told me to come back for blood work in 6 weeks from then (so the medication can take full effect) ok. Cool. Did that and had another follow up, what the doctor told me was that my thyroid levels were slowly decreasing and becoming in the right range for pregnancy but my prolactin levels had not decreased at all. So now we must treat both.   He prescribed me dostinex (cabergoline) 5mg to take once a week as well as the Synthroid daily.   The dostinex itself I haven’t been feeling any side effects shockingly, but that might be cause I ALREADY suffer from severe anxiety lol. But one thing I did notice was my period only lasted 2 full days this cycle (first cycle with dostinex) when usually it would be a full 5-7 days. Should I be worried about that? Or could it be that my body is adjusting to everything…? I don’t understand why my period would be so short, never has been.   I am just feeling very overwhelmed and discouraged with how long the process is taking to get my hormones into the right range to ACTUALLY start a treatment plan… I feel like there isn’t much I can do until then?   I’d love to hear if anyone else has had a situation like this or has been prescribed dostinex (cabergoline) for high prolactin levels for trying to conceive, if you were – what was the outcome? How long did it take you to get your BFP?! Was there any changes in your cycle or period length? Any advice would be appreciated, just trying to give myself a peace of mind. Next steps are to do a follow up blood test beginning of February – if my prolactin and thyroid levels are increasing as they should be, I will be starting IUI and ovulation induction next cycle (going into March). That is only if, my hormones are in the right range finally.