If you can relate please comment !!
So I (19) (F) had had once a year since I was 12, in 2014, a random severe cramp sensation for a whole day and I would not be able to stand up straight without pain and I wouldn't be able to pee without this severe cramp from my belly button that felt like inside someone was pulling on a tight string attached to behind my belly button... I have been to the ER every time it happens, they tested my urine and blood. No utis, no infections, nothing even showed up on CT scans!! Doctors are as confused as me. They gave me Toridol thru IV to help with the pain. In 2019 I was tested for a rare thing called Anterior Cutaneous Nerve Entrapment Syndrome. It is your nerves firing and saying they're in pain when they're not in pain, if that makes sense. It's pain due to entrapped nerves in the abdominal wall. So just pain in the abdominal wall for no reason just because the nerves are upsetti Spaghetti haha. I am thinking it is due to Anterior Cutaneous Nerve Entrapment Syndrome, because, when I was diagnosed with it in 2019, they prescribed me gabapentin, which is a Nerve/ muscle relaxer, and after taking it since then until today in 2021, I haven't had this pee cramp since before I got on gabapentin in 2019.
I have ACNES aka nerve compression syndrome. Repetitive movements will shrink the nerve and cause it to misfire. I, unfortunately, have it in a place where repetitive motion is not optional. Unless I want to lay on your back 14 hours a day, I will continue to compress my nerves and they can't heal.
Hello everyone, I’ve been experiencing abdominal pain for close to 2 years. I’ve seen several doctors last year and been through ultrasound, endoscopy, MRI and CT scan but unfortunately, can’t find the cause of the pain...
Recently, i chanced upon an article on abdominal cutaneous nerve entrapment (ACNES) and the symptoms described is very much what I’m experiencing. However, I’m unable to find any doctors online in Singapore that treats this condition. I would greatly appreciate any doctor recommendations or sharing of ways on how to cope with the condition if you have any experience on this. Thank you in advance!
[UPDATE]: Went to a pain specialist and it turns out that I have a small umbilical hernia rather than ACNES that is likely to cause of the pain. Kind of annoyed that several gastroenterologists I’ve seen last year did not propose an abdominal wall ultrasound to diagnose this condition earlier but perhaps I went to the wrong doctor and this is not in their area of expertise. Nevertheless, glad to finally discover the cause and hope to get treated soon. Thank you everyone! Stay safe and take care :)
Take a look at this. I think it can be helpful. Let’s open this up for discussion....
https://en.m.wikipedia.org/wiki/Anterior_cutaneous_nerve_entrapment_syndrome
*IBS.
This might be a stretch of a question but I [M 20] was diagnosed with ACNES and was wondering if there are any redditors who also have this nerve syndrome. I would love to hear your experience.
From what most people on here have told me, pelvic floor tightness needs to be addressed before pelvic floor weakness, and its better to do stretching for several months and then move on to kegels once its no longer too tight. But how about hip and glute stability exercises? Should I also wait several months before doing them? Or are they less harsh on the nerve? For me, both kegels and hip exercises inflame the nerve, but kegels inflame it about 4 times more, whereas hip stability exercises just cause a mild ache and spasms that don't last long, unlike kegels, which can cause pain even the next day. Is mild perineum pain from exercise ok as long as it helps stabilize the perineum in the long term?
Hi all,
I'm a 17 yo male, I'm 5'10 and I weigh ~135 lbs. Since about a year ago, I've had a dull pain that runs down the back of my right thigh and worsens the longer I sit or stand still. The pain mostly goes away when I'm constantly moving, such as walking or running, or when I lie down.
Recently, I've also noticed that I have a slight pelvic tilt where my right hip is higher than my left hip. Additionally, I've noticed that my obliques are significantly more pronounced/stronger on my left side and my left leg is not as flexible as my right leg when I stretch.
Could my leg pain be caused by my lateral pelvic tilt? What can I do to fix both of these issues?
Thanks for your help!
This seems like something I should check out due to her constant abdominal pain that isn't caused by gastro issues. She exhibits a positive Carnett's sign. http://www.thepermanentejournal.org/files/Summer2002/acnes.pdf I'm just not sure who she should see.
She has random moments throughout the day where she is in too much pain to even walk. She’s tried everything the doctors have told her to do including lidocaine injections and what not. But I was just wondering if anyone else on here has this issue and knows of anything we can do at home to help with the pain. Thank you.
I’m (46F) moderately hypermobile and I’ve had this combination of symptoms for several years. No physio has ever really put a name or a diagnosis on it or managed to treat it. I’m pretty sure it has to do with the very common problem of sitting down too much, which leads to shortened hip flexors and poor back posture, but that’s just it: that’s very, very common, but the pain I’m having and the location of the pain seems unusual - otherwise every physio would be able to diagnose it in a second.
I feel like it started after pregnancy about six years ago - maybe my core muscles never recovered properly? It gets worse when I sleep in a too-soft bed or in weird positions due to my child coming into my bed, a bad pillow, or not enough room. I have a very limited range of sleeping positions that give relief and allow me to relax properly. The soreness at the front of my hips, between the iliac crest and the groin, is more or less constant. If I sit too long or in the wrong way I get shooting, aching nerve pain in my butt and the backs of my thighs. Sleeping flat on my belly, which can happen if the pillow is not supportive enough, is hell - I wake up feeling like I’ve been run over by a truck and I can hardly get out of bed.
My hypermobility is mostly peripheral, but I’m tall with a long upper body and I’m aware that my hip area, as well as the small of my back, is a weak spot where I tend to have a lot of tension.
Does anyone recognize this combination of symptoms, or can shed any light on exactly what muscles might be involved, so I can research the right exercises for it? TIA!
ETA: I looked up pelvic clocks and boy, do they hurt. Every single inch of movement hurts somewhere, either my back or my front. Should I still do them?
Literally every single day since I was diagnosed, I’ve felt nerve pain on my inner thighs, whether I’m having an OB or not. What medications/treatments/home remedies will help with this?
Hey,
I've been reading some interesting bits and pieces around the place and wanted to know if anyone has had a chance to try out Trans-cutaneous Vagus Nerve Stimulation? It looks really positive and drug free with positive effects on pain levels, depression, and anxiety. For me that's a massive win win. But the catch is it's not widely available.
For those interested you can find more here:- Google Scholar
So let me start off with some identifying information:
Age : 27 (28 in october)
Sex : M
Height : 5"10'
Weight : 74 kg
Race : Middle Eastern.
Duration of complaint : 3 years
Location (Geographic and on body) : I donated a part of my liver in 2010 for my cousin who contracted Dengue and Hepatitis C. I have an inverted capital T shaped stitches on my chest (directly in the center, barely a cm or two from the belly button)
I don't wanna give my physical location, but let's just say its a muslim country around India.
Any existing relevant medical issues (if any) : None that I know of. Family has issues of heart disease, diabetes, baldness, vision, I managed to skip all that.
Current medications (if any) : None.
Include a photo if relevant (skin condition for example) : I can't post as the pain is under my skin.
With that out of the way, let me get down to my story.
In 2014, I was running super late for my 9AM class in college, I was 10 minutes late for my presentation. I was sprinting like an athlete. I was used to running / walking frequently because of the size of my campus, and classes being on polar opposites of the campus.
I was running on the ground floor to the stairs when I suddenly slipped. I thought the floor was wet but there was no water or any thing slippery around me or my feet.
I got to my feet, tried to run again and I fell immediately.
I tried to get up again and I couldn't. I felt like heavyweight champions were forcing my legs down. I had to support myself against the wall and limp to class on the 3rd floor.
I managed to deliver the presentation, and right after, stayed sitting in my seat. Called a friend who rushed me to the on-campus infirmary. From there, the nurses were unable to help me and called the ambulance for me.
I went to my family doctor and he said I have Anterior Cutaneous Nerve Entrapment Syndrome.
He gave some extremely potent meds for it, which would knock me out for hours on end. Once my first dosage finished, my family discontinued my treatment. no one believed I me and said I was faking it to get out of studies, when I maintained a B+ average throughout my college with american grading system in place.
Fast forward to 2015. it happens again. I am listening to music and I suddenly am completely vegetable. I can't move at all. legs have given out and suddenly no energy. Friends saw me not moving and rushed me to the on-campus infirmary.
I was injected with something, went to sleep and
... keep reading on reddit ➡Hello! I (21F) am finally seeing a neurologist in the upcoming weeks, but it’s been a while to get there. I was having back pain last September, which led to my right thigh becoming super sensitive. I would be sitting down and flex my leg in any way and immediately be in excruciating pain making me scream out. I couldn’t pick up anything more than 10 pounds or move my leg much. Constantly feeling every sensation in the book going on inside my leg. The top of my right thigh was so sensitive. I finally went to my hospitals orthopedic unit. The doctor walked in and said I probably had a pinched nerve. He said “and I bet this hurts” then poked my leg, hard, 6 times. I think me screaming out in pain made him realize he shouldn’t have done that. I was taken for an X-ray for my thigh and they saw nothing. I was sent home and referred to their spine specialist. I had an X-ray and mri of my back done, then said I had a slightly arthritic (I forget the big name) L-5 / S-1 disc. He sent me to get two steroid shots to help with back pain and told me the leg pain should get better. It didn’t. I got the shot in December. I was back in February after waiting 6 weeks to see if it would help. I got an mri of my thigh, and nothing. I got a never study done on my leg and nothing. I have tried steroids on two separate occasions. I tried taking gabapentin and that didn’t help. I then tried lyrica and that does not help. The spine specialist just said we should do a nerve block to see if it will get rid of the pain. And if it does, we can keep doing it. I felt like he was just done trying to help and didn’t want to refer me to someone else. I then saw a physician, a new one, as I was aging out of my pediatrician. She got ALL my blood work done, and everything normal. She had since tried helping me get in to see a neurologist, the first place was 8 weeks out, then called to reschedule my appointment twice due to scheduling reasons. I was frustrated and asked her to refer me to a new place. Anywhere I call won’t even tell me what their soonest appointment is without a referral. I am supposed to see the new place 7/26. I am so sad to realize I have gone almost a full year, being in pain. I can’t do simple things that I enjoy anymore. No hikes. Even doing the kitty litter hurts my leg. I am just about in tears every night because of the pain, and I can’t get comfortable in any position because of the sensitivity of my thigh, and I wake up wanting to cry because I am already in pain
... keep reading on reddit ➡
I’m black M, 50, 180lbs, pain is on front/side of thigh from hip down to knee, I’m not on any meds but I’ve been taking 400mg ibuprofen daily. I’ve also been diagnosed with sciatica which left my right buttock and bottom of my feet numb for almost a year. Now the numbness is gone but a slight ache in the lower back persists.
This shock feeling happens once every other week or so. It’s extremely albeit briefly painful. I tried to do a femoral flossing exercise which immediately trigger another episode. It lasts for a few seconds and then it’s gone, leaving me a paranoid mess for a couple of days afraid of when it’ll happen again. Could it be meralgia paresthetica?
Any advice on what I should do and any temporary treatment I can apply to avoid another?
Haven't been able to understand this question. I answered contralateral (answer is ipsilateral) because I assumed all corticospinal fibers decussate at the lower medulla.
Topline study results expected in the first half of 2022
Biologics License Application (BLA) filing anticipated in the second half of 2022
CRANFORD, N.J., Dec. 6, 2021 /PRNewswire/ -- Citius Pharmaceuticals, Inc. ("Citius" or the "Company") (Nasdaq: CTXR), a late-stage biopharmaceutical company dedicated to the development and commercialization of first-in-class critical care products with a focus on oncology, anti-infective products in adjunct cancer care, unique prescription products, and stem cell therapies, today announced that it has completed patient enrollment in its Pivotal Phase 3 trial of I/ONTAK, an engineered IL-2-diphtheria toxin fusion protein, for the treatment of patients with persistent or recurrent cutaneous T-cell lymphoma (CTCL). The treatment phase for the study has been completed with topline results expected in the first half of 2022 and a biologics license application (BLA) expected to be filed with the U.S. Food and Drug Administration (FDA) in the second half of 2022.
"Completing enrollment in the Pivotal Phase 3 study of I/ONTAK moves us another step closer to expanding treatment options for patients suffering from advanced CTCL. We expect I/ONTAK's unique mechanism-of-action to offer oncologists an important therapeutic alternative to current targeted therapies which have limited duration of response and are often discontinued due to toxicity. We look forward to reviewing the complete safety and efficacy data and anticipate providing topline results in the first half of next year, followed by a BLA submission in the second half of 2022," stated Myron Holubiak, Chief Executive Officer of Citius.
A total of 70 patients were enrolled in the main part of the I/ONTAK Phase 3 study, a multicenter, open-label, single-arm Pivotal study of I/ONTAK in participants with recurrent or persistent CTCL (NCT01871727). Positive efficacy data from an initial 21-subject lead-in study supported proceeding with the main study with an optimal dose level of 9 micrograms per kilogram (mcg/kg) of I/ONTAK. Subjects w
... keep reading on reddit ➡