Extrapyramidal Side Effects in a Patient with Alcohol Withdrawal Symptoms: A Reflection of Quality of the Mental Health Care System researchgate.net/publicat…
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πŸ‘€︎ u/kmarkmohan
πŸ“…︎ Jul 01 2021
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Hopantenic acid (Pantogam)

Any experiences with this? Can barely find anything about it.

>Hopantenic acid is a substance that combines the neurochemical and pharmacological properties of both GABA and pantothenic acid. It acts as a precursor and analogue of both of them.
>
>In contrast to both GABA and pantothenic acid, hopantenic acid readily crosses the blood-brain barrier. Due to that, it affects both the GABAergic systems of the brain and the systems that depend on the participation of pantothenate and its derivatives (coenzyme A and acetyl-CoA).
>
>Through its action on coenzyme A and acetyl-CoA system, it influences all the main neurotransmitter systems (dopaminergic, noradrenergic, serotonergic, cholinergic, glutamatergic), the metabolism of cholesterol and phospholipids, antioxidant systems and alike. Hopantenic acid has a wide spectrum of therapeutic activity. It has neuroprotective, neurotrophic, neurometabolic, nootropic (procognitive), antidepressant, anxiolytic, moderate antipsychotic, antinegative and analgesic effects, and also has the ability to reduce the extrapyramidal side effects of antipsychotics.

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πŸ‘€︎ u/struggling_123
πŸ“…︎ Jun 06 2021
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What do you call a man with no arms or legs in a hole?

Phil

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πŸ‘€︎ u/Rumblebully
πŸ“…︎ Jun 30 2021
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Did you know Bruce Lee has a faster older brother?

Sudden Lee

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πŸ“…︎ Jul 02 2021
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DAD JOKES ARE NOT DIRTY.

Go post NSFW jokes somewhere else. If I can't tell my kids this joke, then it is not a DAD JOKE.

If you feel it's appropriate to share NSFW jokes with your kids, that's on you. But a real, true dad joke should work for anyone's kid.

Mods... If you exist... Please, stop this madness. Rule #6 should simply not allow NSFW or (wtf) NSFL tags. Also, remember that MINORS browse this subreddit too? Why put that in rule #6, then allow NSFW???

Please consider changing rule #6. I love this sub, but the recent influx of NSFW tagged posts that get all the upvotes, just seem wrong when there are good solid DAD jokes being overlooked because of them.

Thank you,

A Dad.

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πŸ‘€︎ u/Von_Bostaph
πŸ“…︎ Jun 18 2021
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I've asked so many people what LGBTQ stands for

So far nobody has given me a straight answer

πŸ‘︎ 7k
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πŸ“…︎ Jul 04 2021
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Pulled a Dad Joke on a Nurse

I am currently in the hospital. I had a back operation yesterday. The surgical nurse came in my room and started asking questions about my back. She asked me if I had any falls during the last year. I responded just one. It was after summer.

She laughed and said in 20 years of doing this she never was told that joke.

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πŸ‘€︎ u/rei_920
πŸ“…︎ Jul 07 2021
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Why should you never brush your teeth with your left hand?

Because a toothbrush works better

πŸ‘︎ 9k
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πŸ‘€︎ u/ravenhiss
πŸ“…︎ Jul 10 2021
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What’s the difference between an Indian restaurant and a Vietnamese restaurant?

Indian places are naan profit, Vietnamese places are pho profit.

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πŸ‘€︎ u/WVU_Benjisaur
πŸ“…︎ Jul 08 2021
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I wanted to share a victory with you guys!

For the past couple years I've been on Zyprexa for PTSD and Manic Depression.

I always had a restlessness problem where every time I would have stimulants like caffeine I would not be able to sit still and I'd get trapped in obsessive thought loops. I always just wanted to be able to relax and play video games for hours on end and zone out, but the restlessness would make me pace around the house.

In the past couple months I've been trying an antidepressant (Prozac) to keep me from having intrusive thoughts and other depression issues. Because of I have been improving drastically my psychiatrist agreed that I can now go on a lesser dose of the Zyprexa.

After cutting the dose of the medication in half I am finally able to consume caffeine without pacing around and getting lost in thought loops and I was even able to play video games for a few hours each day with no issues whatsoever!

My brain and body feel so fluffy and light because of the lack of or lessening of the extrapyramidal symptoms. I cant express how grateful I am that my internal motor is not going on overdrive at all times!

I just wanted to share this victory with you guys. Every time I put the puzzle pieces of my nervous system back together I am always extremely happy and proud of myself for being courageous enough to stand up for myself and make changes.

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πŸ‘€︎ u/thebigsodaboi
πŸ“…︎ Jun 05 2021
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Anyone who can spell the word drawer backwards...

..... Will get a reward.

πŸ‘︎ 11k
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πŸ‘€︎ u/VERBERD
πŸ“…︎ Jul 04 2021
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I'd ruther not say
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πŸ‘€︎ u/Un_FaZed211
πŸ“…︎ Jul 01 2021
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Why are elevator jokes so good

Because they work on many levels

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πŸ‘€︎ u/The_Fox1984
πŸ“…︎ Jul 05 2021
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Rational
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πŸ‘€︎ u/mainhoonmadrasi
πŸ“…︎ Jun 30 2021
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Who were the greenest Presidents in US history?

The Bushes

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πŸ‘€︎ u/caverypca
πŸ“…︎ Jul 09 2021
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My wife blocked me on Facebook because I post too many bird puns.

Well, toucan play at that game.

πŸ‘︎ 9k
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πŸ‘€︎ u/Zayan-ali
πŸ“…︎ Jun 30 2021
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Interviewer : why should we hire you as a waiter?

Me : For starters, I bring a lot to the table

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πŸ‘€︎ u/Motor_Fox_9541
πŸ“…︎ Jul 08 2021
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Argon enters a bar, the bartender says β€œWe don’t serve noble gases here.”

Argon does not react.

πŸ‘︎ 7k
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πŸ‘€︎ u/Dick_Squeakly
πŸ“…︎ Jul 06 2021
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If Apple made a car what would it be missing?

Windows

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πŸ‘€︎ u/Moplex1234
πŸ“…︎ Jul 02 2021
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There are only two white people in the movie Black Panther

Martin Freeman, and Andy Serkis.

They also play roles in Lord of the Rings.

I guess that makes them the Tolkien white guys.

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πŸ‘€︎ u/jzagri
πŸ“…︎ Jun 24 2021
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Just saw on the internet
πŸ‘︎ 4k
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πŸ‘€︎ u/PN341720
πŸ“…︎ Jul 09 2021
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My 3 yr old daughter made her first pun today and I almost cried. She was eating an apple and I asked her if she liked apples.

She said apple-lutely

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πŸ“…︎ Jun 29 2021
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He needs grounded
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πŸ‘€︎ u/AthanasiaStygian
πŸ“…︎ Jul 06 2021
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"ground" the kid
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πŸ‘€︎ u/freakynit
πŸ“…︎ Jul 03 2021
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My son accidentally handed me a dad joke on a platter and it was glorious.

This happened a few years ago when my son was 6ish. When my kids hurt themselves and it doesn’t look serious I always do the β€œwe might have to amputate that bruised hand” shtick with them. I’ve done it enough that they now roll their eyes.

So, my son got hit lightly in the face with a rubber ball. It wasn’t a hard hit and I could tell he was more upset by the shock of it rather than the pain. So I say β€œlooks like we will have to amputate your nose.” To which he replies β€œthen how will I smell?” And I say β€œterrible!”

It was my greatest dad joke ever. I felt like I could retire after that.

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πŸ‘€︎ u/perryt2007
πŸ“…︎ Jul 08 2021
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If I had 50 cents for every math Exam I failed

I’d have $8.40

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πŸ“…︎ Jul 09 2021
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MMM, burgers
πŸ‘︎ 5k
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πŸ‘€︎ u/mkxviii
πŸ“…︎ Jul 08 2021
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What did the left eye say to the right eye when they got married?

'Eye-do'

This is my first post pls don't kill me lol.

The people in the comment section is why I love this subreddit!!

Cred once again my sis wants credit lol

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πŸ‘€︎ u/tieyz
πŸ“…︎ Jun 27 2021
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Well there goes his reproductive fitness...
πŸ‘︎ 6k
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πŸ‘€︎ u/annnnnnnnie
πŸ“…︎ Jul 05 2021
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Need some hope

Been dealing with taking 30 x 30mg adderall over the course of one week in a month for the past several years. I’ve noticed some health issues arise from it that freak me out all the time. I know no one is a doctor/allowed to diagnose. Im just Too scared and ashamed to speak to a doctor. And need reassurance or something?

I’ll get bad extrapyramidal symptoms that have resulted in me uncontrollably knocking things over. Tongue movements, slack jawed, twitches, muscle constructions. Goes away after I sleep thank god. But makes my nervous system itch and burn and writhe while I experience it. It’s the worst sensation I’ve ever felt

Muscles Have gotten weaker and weaker over the months

Skin turns orange almost instantly now

Anger issues Increased

Have a desire to stop but have shown no signs of being able to.

On top of that, I’m bipolar, have anxiety disorder, and drink too much. I’m kind of a mess right now.

Any kind words or insight or help would be great. Please no, β€œyou’re dying!!!” Type responses. I’m already always freakin out about my health.

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πŸ‘€︎ u/cat-pants
πŸ“…︎ May 09 2021
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Proud dad moment.

Keep in mind, my son is 4 years old, so everything is an original to him.

I had to work late into the evening yesterday, and he was just going to bed when I got home. I had left home for the office nearly 14 hours prior, had a long day, lots of meetings, traffic, etc.

When I walked through the door, I was exhausted, run down, and starving. My wife hugged me and asked how my day was, and I replied, "Done. It was a good day, but has got me exhausted. I just want to grab a bite and go to bed. I'm hungry."

From my son's bedroom, I hear him shout, "Hi Hungry! Nice to meet you!"

Not only did it make me laugh, but I completely forgot about how hungry and tired I was. I went to his bedroom, and we laughed together about it. It was exactly what I needed.

Edit: Thanks for all the awards, kind strangers! I'll let my son know y'all enjoyed his joke too!

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πŸ‘€︎ u/LaBarbaGuapa
πŸ“…︎ Jul 01 2021
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What was a very common name in the middle ages?

I heard parents named their children lance a lot.

First post please don't kill me

Edit: i went to sleep and now my inbox is dead, thank you kind strangers for the awards!

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πŸ“…︎ Jun 24 2021
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so many choices
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πŸ‘€︎ u/SailorNebula
πŸ“…︎ Jun 07 2021
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Why did the toilet paper roll down the hill?

To get to the... Bottom...

(as told by my 5yo son, I'm so proud)

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πŸ‘€︎ u/wotmate
πŸ“…︎ Jul 05 2021
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Gottemm
πŸ‘︎ 8k
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πŸ‘€︎ u/Un_FaZed211
πŸ“…︎ Jun 29 2021
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Apologies if it's a bit corn-y
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πŸ‘€︎ u/mediashiznaks
πŸ“…︎ Jun 26 2021
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What pan is the best to make sushi in?

Japan.

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πŸ‘€︎ u/Most-Stomach4240
πŸ“…︎ Jul 01 2021
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Well that didn't cross my mind
πŸ‘︎ 6k
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πŸ‘€︎ u/JasonPetreasCoach
πŸ“…︎ Jun 11 2021
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I just don't understand why some people are so adverse to vacuums...
πŸ‘︎ 3k
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πŸ“…︎ Jul 10 2021
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He knows too much
πŸ‘︎ 6k
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πŸ‘€︎ u/Potato_salad123
πŸ“…︎ Jun 24 2021
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My inflatable house got a puncture last night.

Now, I'm living in a flat.

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πŸ‘€︎ u/VERBERD
πŸ“…︎ Jul 09 2021
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I said to my wife, "I need to call the doctor today." Concerned, she asked, "Which doctor?"

"No, the regular kind!" I laughed.

πŸ‘︎ 8k
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πŸ‘€︎ u/808gecko808
πŸ“…︎ Jul 03 2021
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where do pirates get their hooks?

second hand stores!

πŸ‘︎ 7k
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πŸ‘€︎ u/bigus-_-dickus
πŸ“…︎ Jun 25 2021
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I've just deleted all the German names off my pre owned iPhone..

it's Hans free now..

πŸ‘︎ 7k
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πŸ‘€︎ u/HugoZHackenbush2
πŸ“…︎ Jun 28 2021
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Charjar Binks
πŸ‘︎ 2k
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πŸ‘€︎ u/MrCloud-YT
πŸ“…︎ Jul 04 2021
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