Hey friends. First post here, long time sufferer of CHS. First started probably 7 years ago and was miserable for a couple years before I got diagnosed. Anyway, about a year ago, my doctor prescribed me nortriptyline for my insomnia. I started taking 75mg a night. Since I’ve started the nortriptyline, I can smoke pretty much like a normal person. I used to get sick after a day or two smoking in a row, and I’ve now been a year straight without getting sick. Through my experiments with it, amitriptyline also works, with a dose of around 100mg per night. My dad has the same exact issue (CHS) and he also started taking it and we’ve both been fantastic since. I can’t promise a miracle cure, but it’s been amazing for me. Every once in awhile I’ll wake up feeling a little stomach pain, but I just take that day off from smoking and continue the next unaffected.
Might be worth a try. Sorry to all of you that suffer from this, too. Took me 10 hospitalizations before I figured it out. Worst pain of my entire life by far.
I am on clomipramine and I am wondering if I could take mirtazapine alongside it, mainly to help with sleep (since clomipramine makes it harder for me to sleep) but also to potentiate the effects of the clomipramine. I am worried about serotonin syndrome, although I know that mirtazapine can be used safely alongside venlafaxine (california rocket fuel), so I thought I would ask.
Look, this isn't exactly the best way to do it for normal use, but it's not an overly dramatic statement to say that I have terminal depression, I had absolutely no will to live, and was at the stage of depression where you start giving up on everything and shit yourself, and nortriptyline forced a pharmacological will to live in me in three days of use that I was actually pissed off about after trying to choke myself out with a bed sheet in the psyche ward bathroom. When you're at that point, who gives a fuck about liver issues.
Anyway, I've run out of my medicine recently and it lasts for a few days without taking it if I've been consistent for a while. I'm way past that, and the strange gravitational pull into a black despaire that triggers my trauma and throws me into this loop of... horrible things, so that's a sufficiently dangerous situation for some drastic measures, and I don't mind snorting nutmeg on a good day except for having my nose clogged until I blow it well.
I forced myself to get up and do a line because I'm almost out of food stamps for the month and can only get so much more McCormick at $5 for 30g. I did one earlier too, like more than 5 hours ago, just for a bit more of a buzz, it's a nice ROA for a good buzz, but within minutes of the second line that day I was feeling not horrible anymore not amazing, but enough to be medically lightweight spectacular in comparison to most of the common options. An hour later and I'm proper high and distractible, enjoying my Boards of Canada (Music has a right to children) and might put on a movie. I got some prayer and I'm grateful for nutmeg in my life.
Soon I'll have some EO from Amazon, my Dad sent the numbers of a gift card I can use on amazon (and I'll be getting my prescription filled tomorrow) I'm getting Clove, Nutmeg, and German Chamomile essential oils (I guess I was wrong about the strain of chamomile for elemicin activation, or 69ron was, in an old ass forum comment) as well as mastic gum and nicotinia rustica to make a chewing gum, and a snuff out of these ingredients to see exactly how much of that stuff should be used in each preparation.
Also I'm trying to dig into the therapeutic/psychonautical use of dreams in the context of nutmeg and so mugwort and amanita are being researched right now as well as "dream/sleep yoga" and lucid dreaming in general.
As far as liver stuff goes, mugwort is potentially beneficial, and milk thistle is a STRONG candidate for counteracting, if n
... keep reading on reddit ➡I've been working as a drug detox nurse since February and I am constantly learning new stuff. So today I got a urine from a new admit. I look at the UDS cup and he tested positive for TCA. I asked my coworker what is tca? She was like tricyclic antidepressants. I was like wait like doxepin? She was like Yeah. I said why would we screen for those? And she couldn't tell me. So does anyone here know why? I'm really curious. Thanks!
I know about the correlation between certain illnesses and SSRIs and tricyclic antidepressants, but I was wondering if there was any isolated research done on long-term SNRI usage?
https://www.deadiversion.usdoj.gov/fed_regs/rules/2021/fr0722_2.htm
SUMMARY: The Drug Enforcement Administration proposes placing the substance amineptine (chemical name: 7-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)amino]heptanoic acid), including its salts, isomers, and salts of isomers, in schedule I of the Controlled Substances Act. This action is being taken to enable the United States to meet its obligations under the 1971 United Nations Convention on Psychotropic Substances. If finalized, this action would impose the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess), or propose to handle, amineptine.
DATES: Comments must be submitted electronically or postmarked, on or before September 20, 2021.
How this effects Tianeptine: Under the federal analog act in the USA, if Amineptine is made Schedule 1 in the USA, any Tianeptine sold for human consumption may be treated as it's Schedule 1 related even if not specifically listed under the CSA. There are also laws that allow DHS to seize any structurally related drug of a scheduled substance on import to the USA without specific paperwork.
Hi, I dunno if this is the right subreddit to ask but I figure I’ll start here. I’m tapering off of clomipramine which is an older tricyclic. I’ve been on 100mg for about a year, and this week (I’m on 6th night) I’ve tapered down 25mg (on 75mg for 6 days) and I’m going to go down another 25mg to 50mg next week.
When I was put on this by a psychiatrist, I had to taper up like this each week so I’m just following the same pattern but tapering down.
Anyway, basically I have tried googling but can’t come up with anything. Before taper, I could achieve orgasm fine. Now, I’m tapering, I expected my sex drive etc to maybe be elevated, but it is quite elevated except I can’t achieve orgasm and I’m really confused because since it’s hard to orgasm on antidepressants.. why is this happening to me?
Any thoughts?
It's an old antidepressants so it's hard to find opinions on it. I have been on it for 2 years I think and I feel like yes it has worked at some point but not anymore and I really struggle with memory issues now, want to know if I should talk to my doctor about stopping it. I take that one because I tried all the regular ones but they made me too shaky or nauseous
edit : I think it's also known as "Dosulepin"
This is a antidepressant right? So I must give the supposition that someone abusing this drug for a opioid high, must also be getting a lot of side effects from the drug traditional mechanisms of action on the brain?
The fuck is the point of testing for an antidepressant. And why a TCA out of all of the antidepressants? Mainly seeing them on those Walgreens 14 screen drug tests
I want to use: Bacopa (daily) Niacine (Flush version, daily) Mucuna Pruriens (only on occasion) Rhodolia Rosea (only on occasion)
Anyone knowledge about this or experiences with these combinations?
My doc just tells me he doesnt know much about it.
My friend and I have been planning to take nexus together for a while now, although I've just recently started taking some new tricyclic antidepressants (mirtazapine) a little under a week ago. Previously I've been on 20mg Citalopram which is an SSRI and I found that really attenuated the experience, and information surrounding that combination and the resulting lessened effect can be found quite easily. However I can't seem to find anything about the combination of 2C-B with tricyclic antidepressants. Has anyone here tried this combination before and can offer their experiences as guidance? I obviously doubt there will be any dangerous interactions and worse case scenario it'll attenuate the bees the same way SSRIs do, although I would rather hear from other people if that's the case as opposed to experiment myself and have to spend more time and money on seeing how to go about achieving the kind of effects I'm looking for.
Anybody else here a cigarette / tobacco smoker and on a tricyclic antidepressant?
I’m on 100mg amitriptyline each night and I get some kind of strange sensations after smoking here and then. Amitriptyline also raises my heart rate. Maybe both together is too much for my body?
Anyone having similar experiences or noticing differences while or after smoking since on tricyclic antidepressants?
I've tried the following for depression/anxiety and insomnia:
SSRIs: Lexapro, Paxil, Prozac, Zoloft
SNRIs: Wellbutrin SR, Wellbutrin XR
Tricyclics: Amitriptyline (for insomnia)
Other: Buspar
All of these medications have caused night sweats. I've talked to my PCP and he said that medications that modulate serotonin have this common side effect. I've brought this my psychiatrist and he told me that this is a rare side effect but gave no other advice. What should I do?
Edit: I should mention my current medications are:
Adderall 10mg IR 2x daily, Amitriptyline (As needed for Shift-Work Disorder), Protonix 40mg (As needed), Prozac (10mg), Truvada 200mg, Wellbutrin 200 mg XR, Xanax .5mg (As needed)
Vitamins and supplments: Probotic 6 Billion CFU (once daily), Vitamin C, Zinc
Has anyone suffering from PMDD tried Tricyclic Antidepressants (TCAs) for treatment?
If so, could you share your experience?
I’m almost 30 years old and recently self-diagnosed with PMDD after 10+ years of repeated symptomatic patterns. After years of misdiagnosis and treatment typically with SSRIs and SNRIs — I feel this is something I need to gather information about independently in order to receive proper medical care (and help others!)
Hello All,
EDIT: Everything came in!
This is a little long, so if you just want to see the supplement list of what I am going to start taking, please look at everything below the ************************.
I read a few posts and gathered what I could put together.
I want to wean off tricyclic antidepressants (Mirtazapine 30 MG at night & Desipramine 100 MG in morning) and Klonopin (1 MG bed time) and Propranolol ER (60 MG at bedtime to help with my natural fast heart beat normally stays at 110+, with this medicine keeps it under 90), I have been taking these for 8-10+ Years. Recently Added Wellbutrin XL 150 MG in morning. Also I take Prilosec in the morning and I also want to stop taking that.
I tried CBD Oil and it doesn't do much for me, but I have tried Kratom and it has some amazing effects but I only take it at night, not 3X a day like some others recommend.
I feel like it is possible with Meditation and Supplements, and the willpower. I feel I will be sharper again, and not have cloudy thinking and sexual side effects will be gone. Please give me your insight.
I did try to add Wellbutrin XL 150 MG in morning, took for 4 weeks, and recently doubled to 300 MG, but I got bad anxiety so I went down to 150 MG again. I was hoping if I took this I could take this in the morning and wean off the Desipramine.
I was hoping to move to SSRI from Tricyclic and slowly wean off the SSRI, but for some reason SSRI's do not work for me like tricyclics. I started reading in this group and learned maybe I can use supplements to help me wean off my current (tricyclics) I do want to get off the medicines, due to side effects and put less chemicals in my body. I have for a long time tried to move over to SSRI, as they have less side effects, but I do not know if that is what I should try for, or try to wean off them all.
Any Tips/Help would be appreciated, I usually get anxiety and heart pounding/breathing issues when I have bad anxiety, and Nausea is the main thing I feel when I am down and feel depressed and its a horrible feeling. I really want to cut down the medicines but am super scared these symptoms will come back as when I have the Nausea I just am totally down and I end up getting more worried because I am getting scared that the medicine pills is the only solution, and that these supplements might not work. I feel like its genetic and I have to take the meds because my mom (a
... keep reading on reddit ➡Just tried 1g of shrooms for the first time and I kept waiting for something . . . And basically nothing happened.
I felt a little bit more chilled out, for done annoying muscle weakness, and blues looked a little more green . . . But that's it.
I have read that SSRIs can decrease effectiveness of shrooms-- does the same go for amitriptyline? I'm on a really small dose for migraines.
What is the cause of the acidosis in patients with TCA overdose? I thought it was due to respiratory depression, but then I read that we are talking about metabolic, not respiratory acidosis. Thanks in advance!
Hi folks.
I know SSRI / SNRI antideppresants are more secure than older antidepressants like MAOIs or Tricyclic but I'm not sure of its effectiveness.
Maybe next time I would like to try a tricyclic antidepressant.
How has your experience been with this type of drug? Have your depression improved? Do you feel they work a lot better than SSRI / SNRI?
Why are they sometimes more effective than newer antidepressants ? are they too dangerous to try them? I am interested in imipramine...
Expert question: I tried several antidepressants, SSRIs, tricyclics, Imao, I realized that the ones that have the most beneficial effect on me are those that affect serotonin, however after a few months all antidepressants stop working from one day to the next. else, does anyone have any idea why this happens? Anyone else in this situation? Thank you
