Can someone explain the relation between them? and explain this UW algorithm?
https://preview.redd.it/cprctd2198781.png?width=944&format=png&auto=webp&s=70066fa9352714d3f2c5c1722303f51dc4488043
It's generally due to etiology that may cause "inappropriate" levels of aldosterone.
But why would that result in high urine chloride? Is it due to the aldosterone escape mechanisms (so just less chloride absorbed)?
Hi,
I've been reading about Holotropic Breathwork and hyperventilation breathing in general and it looks like the "high" feeling and possible hallucinations that some have come from the respiratory alkalosis created by increasing the blood PH e.g making the blood more alkaline by lowering the CO2 content (CO2 being an acidic molecule).
So I'm wondering about one thing. If the effects looked for a due to the blood PH increased, wouldn't it help the breathwork to have ingested some sodium bicarbonate before (not right before the breathing but a decent amount several times a day for several days)?
I was thinking of it because sodium bicarbonate is well-known to have a pH of 8.4 and isn't bad for health (at least as far as I know and consumed properly).
What do you guys think?
Cheers
The formula drives the reaction towards making of more CO2...then why does the body try to get more co2 wont it just make the environment more acidic??
I have been experiencing symptoms of alkalosis (nausea, confusion, lightheadedness) amongst a few other symptoms I’m not sure correlate (chest pain almost like heart burn or reflux, despite if I’ve eaten anything or not, extreme chronic fatigue, and severe bouts of depression). I believe most of these symptoms showed up when I started regularly doing the breathwork and cold showers but it’s hard to say. I started regularly to combat the depression mostly, and to help work through some PTSD. And I’ve been continuing it to help with all these other problems but now I’m wondering if it is causing them. Alkalosis can be caused by low CO2 in the body. I have been so proud of myself and excited to be able to do this work everyday, I will truly be so sad if it turns out this is what’s causing all my discomfort so don’t take this post as someone hyper-critical of the method. I believe Wim Hof has an amazing vision for the world and truly has discovered something amazing. I’m just wondering if it’s possible there are downsides, risks, etc? I’m going to pause the work for a while to see what changes but I wanted to hear it anyone else has experienced this before.
First aid section on laxatives says they cause alkalosis but from my understanding of diarrhea loss of bicarbonate causes an acidosis?
Why does chloride depletion (hypochloremia) cause metabolic alkalosis. Besides fluid volume depletion and activation of RAAS, please explain how low chloride directly causes the metabolic alkalosis. And if you can, please explain why hyperchloremia causes metabolic acidosis.
My lecture mentioned that acidosis causes a decrease in neuronal excitibility while alkalosis causes an increase in neuronal excitibilty, however the mechanism of how this happens was not explained.
I tried googling and discovered this answer
However this "answer" raises more questions than it answers. For example, what is the mechanism by which alkalosis cause hypokalemia? and if there's hypokalemia this will cause hyperpolarization which actually should decrease not increase excitibilty so how is this explained?
I understand that vomiting your acid would raise the blood pH, but why does bicarb also go up? Wouldn’t the body compensate by lowering bicarb? Is it because the bicarb can’t be neutralized internally because of a hydrogen ion deficit??? Thanks!
SODIUM IS reabsorbed in the straight portion of the proximal tubule in the cortex and is susceptible to hypoxia
So sodium no longer reabsorbed... cant this cause metabolic alkalosis because the more sodium is sitting in the lumen and in the principal cell will be reabsorbed and it will b similar to aldosterone effect?
Apologies if content questions are not allowed here. I had a quick glance through the rules and didn't see anything saying they are not.
I am a first year medical student, learning about asthma.
In my lectures, the teachers have mentioned that asthma gives a respiratory acidosis due to air retention from the obstruction and CO2 can't get out. That makes sense.
However on Calgary guide (http://calgaryguide.ucalgary.ca/wp-content/uploads/image.php?img=2014/09/Asthma-Findings-on-Investigations.jpg), it says that metabolic alkalosis is present (from the hyperventilation).
Can someone clarify which is true?
My understanding is that during an asthma attack, the hyperventilation would cause respiratory alkalosis, but normally the patient would have respiratory acidosis. Is that correct?
Thank you so much!
Tank was tested high in PH after I looked up some details about what my galaxy koi was doing (I at first assumed he was just excited to see me as he usually is) going back and forth against the glass and turning and going up and down I eventually looked it up and it seemed to be either him seeing his reflection or alkalosis which got me more paranoid about his well-being and if he has ick or anything of that sort and it’s hard to tell with his shiny scales. Does he look okay? I’ll add pictures in the comments
I always thought I understood the idea behind contraction alkalosis, but I just got myself twisted up and am hoping for some clarification. My understanding is that when blood volume decreases, aldosterone increases sodium reabsorption and H+ excretion while ATII increases Bicarb reabsorption/synthesis. This is what raises the pH and inadvertently creates alkalosis while restoring blood volume.
My confusion is, diarrhea is said to cause normal anion gap metabolic acidosis. But diarrhea causes iso-osmotic volume contraction. So wouldn't that trigger the RAAS system and lead to metabolic alkalosis?
Can anybody simplify respiratory and metabolic acidosis and alkalosis for me. Taking the advanced national in a few weeks and think I’m competent enough in every aspect except knowing and identifying acidosis and alkalosis.
So I learned from my biochem class that when respiratory acidosis/alkalosis occurs, metabolic mechanisms come in to fix it and bring the body back to normal and vice versa.
Is it possible for the body to use the same mechanism to fix the problem like if metabolic acidosis or alkalosis occurs, the body uses metabolic mechanisms to fix the problem? Or is this just unheard of?
Thanks!!
https://imgur.com/a/WHHUx2Z
Would someone please be able to explain how increased aldosterone results in "new bicarb reabsorption in contraction alkalosis?
I understand that aldosterone would increase H+ secretion in the distal nephron but I don't get what "new bicarb" reabsorption is
I have a compensated metabolic alkalosis after the first week of vegan keto. I can't figure out why. I have heart palpitations and some agina pectoris.
What can I do?
When I started in the first days I used very low amounts of salt and got very bad keto flu and cramps.
Then I used sodium chloride, potassium gluconate, magnesium malate and very little calcium orotate.
And the heart symptoms which started with the bad keto flu got worst. Now I switched to potassium chloride and very little magnesium malate and still lots of sodium chloride. But it is not much better.. My pulse rate is jumping up and down every second 2-3 beats and the stress level measured by my smart watch is also very high.
I have very low stomach acid and use betaine hcl
What do I do wrong?
Why is urinary chloride high in this scenario. For example, with excess aldosterone wouldn't that increase Na+ and therefore Cl- absorption. Thus, this would decrease the level of Cl- in urine.
