Depletion of ST6GALNACIII retards A549 non-small cell lung cancer cell proliferation by downregulating transferrin receptor protein 1 expression sciencedirect.com/science…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/montaukwhaler
πŸ“…︎ Aug 28 2021
🚨︎ report
Transferrin receptor is another receptor for SARS-CoV-2 entry biorxiv.org/content/10.11…
πŸ‘︎ 26
πŸ’¬︎
πŸ‘€︎ u/icloudbug
πŸ“…︎ Oct 23 2020
🚨︎ report
[ASAP] Enhanced in Vivo Blood–Brain Barrier Penetration by Circular Tau–Transferrin Receptor Bifunctional Aptamer for Tauopathy Therapy

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b11490

https://ift.tt/39ngZ7m

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/TomisMeMyselfandI
πŸ“…︎ Feb 11 2020
🚨︎ report
Soluble transferrin receptor levels in assessing anemia?

Hey all! I'm studying iron metabolism and testing currently, and I'm a bit confused about the sTfR testing. From my understanding, as an RBC matures in the BM, it cleaves off the extracellular portion of transferrin (the sTfR.) Why would an elevated sTfR level be indicative of anemia? Wouldn't that mean you have more RBCs maturing into circulation, which I would assume is a good thing.

Or maybe I just answered my own question. If you have "more than a normal" amount of RBCs maturing, then you are pushing them out because of RBC loss... I have no idea if I just connected those in the right way, so please, correct me if I'm wrong! Thank you, lovely MLS'. :)

πŸ‘︎ 3
πŸ’¬︎
πŸ‘€︎ u/hyphaeheroine
πŸ“…︎ Mar 01 2020
🚨︎ report
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax science.sciencemag.org/co…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/Nymeria12345
πŸ“…︎ May 13 2018
🚨︎ report
Don't google tf TrollDespair
πŸ‘︎ 180
πŸ’¬︎
πŸ‘€︎ u/NotSoFreezy
πŸ“…︎ Sep 19 2021
🚨︎ report
SERIOUS: This subreddit needs to understand what a "dad joke" really means.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

πŸ‘︎ 17k
πŸ’¬︎
πŸ‘€︎ u/anywhereiroa
πŸ“…︎ Jan 15 2022
🚨︎ report
Blind Girl Here. Give Me Your Best Blind Jokes!

Do your worst!

πŸ‘︎ 5k
πŸ’¬︎
πŸ‘€︎ u/Leckzsluthor
πŸ“…︎ Jan 02 2022
🚨︎ report
This subreddit is 10 years old now.

I'm surprised it hasn't decade.

πŸ‘︎ 14k
πŸ’¬︎
πŸ‘€︎ u/frexyincdude
πŸ“…︎ Jan 14 2022
🚨︎ report
Dropped my best ever dad joke & no one was around to hear it

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies πŸ˜‚

πŸ‘︎ 20k
πŸ’¬︎
πŸ‘€︎ u/Vegetable-Acadia
πŸ“…︎ Jan 11 2022
🚨︎ report
What starts with a W and ends with a T

It really does, I swear!

πŸ‘︎ 6k
πŸ’¬︎
πŸ‘€︎ u/PsychedeIic_Sheep
πŸ“…︎ Jan 13 2022
🚨︎ report
Why did Karen press Ctrl+Shift+Delete?

Because she wanted to see the task manager.

πŸ‘︎ 11k
πŸ’¬︎
πŸ‘€︎ u/Eoussama
πŸ“…︎ Jan 17 2022
🚨︎ report
So 2 trees got arrested in the town I live...

Heard they've been doing some shady business.

πŸ‘︎ 7k
πŸ’¬︎
πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
🚨︎ report
What is the scariest tree?

BamBOO!

πŸ‘︎ 6k
πŸ’¬︎
πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
🚨︎ report
What is a a bisexual person doing when they’re not dating anybody?

They’re on standbi

πŸ‘︎ 11k
πŸ’¬︎
πŸ‘€︎ u/Toby-the-Cactus
πŸ“…︎ Jan 12 2022
🚨︎ report
Geddit? No? Only me?
πŸ‘︎ 6k
πŸ’¬︎
πŸ‘€︎ u/shampy311
πŸ“…︎ Dec 28 2021
🚨︎ report
I wanna hear your best airplane puns.

Pilot on me!!

πŸ‘︎ 3k
πŸ’¬︎
πŸ‘€︎ u/Paulie_Felice
πŸ“…︎ Jan 07 2022
🚨︎ report
E or ß?
πŸ‘︎ 9k
πŸ’¬︎
πŸ‘€︎ u/Amazekam
πŸ“…︎ Jan 03 2022
🚨︎ report
Which actor drives the least?

Christopher Walken

πŸ‘︎ 3k
πŸ’¬︎
πŸ‘€︎ u/TR1771N
πŸ“…︎ Jan 18 2022
🚨︎ report
What did Spartacus say when the lion ate his wife?

Nothing, he was gladiator.

πŸ‘︎ 9k
πŸ’¬︎
πŸ‘€︎ u/rj104
πŸ“…︎ Jan 15 2022
🚨︎ report
Pun intended.
πŸ‘︎ 5k
πŸ’¬︎
πŸ‘€︎ u/Sharmaji1301
πŸ“…︎ Jan 15 2022
🚨︎ report
No spoilers
πŸ‘︎ 9k
πŸ’¬︎
πŸ‘€︎ u/Onfour
πŸ“…︎ Jan 06 2022
🚨︎ report
Covid problems
πŸ‘︎ 7k
πŸ’¬︎
πŸ‘€︎ u/theincrediblebou
πŸ“…︎ Jan 12 2022
🚨︎ report
These aren't dad jokes...

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

πŸ‘︎ 12k
πŸ’¬︎
πŸ‘€︎ u/Lance986
πŸ“…︎ Dec 15 2021
🚨︎ report
Low platelets and pain under the ribs on my right side

I am in week 29 and during a few weeks I have had pain on my right side during the evenings only. The pain is quite mild and has not been getting worse.

I mentioned the symptoms at my appointment (I have more frequent appointments due to gestational diabetes) and was sent for some extra lab tests, but the liver enzyme levels were fine and I think that the tests they did for hemolysis were ok too. At least nobody mentioned anything about it.

They didn't do the same tests that I see information about online to test for HELLP syndrome, but similar ones. The transferrin receptor levels were borderline high. That could be because of my iron deficiency anemia though (that has been improving). Blood pressure and all other test results are fine and my only other symptom is swollen feet (except for SI-joint pain but I guess that's unrelated to this).

I took different tests four days apart, but the platelet levels had decreased even more during that time. They are not very low (1st test 150, 2nd test one month later 132, 3rd test four days after second test 129), but going down. I'll have another test in a week.

Has anyone else experienced similar symptoms?

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/BlueDolphinFairy
πŸ“…︎ Aug 13 2021
🚨︎ report
Spi__
πŸ‘︎ 6k
πŸ’¬︎
πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 11 2022
🚨︎ report
What did 0 say to 8 ?

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

πŸ‘︎ 9k
πŸ’¬︎
πŸ‘€︎ u/designjeevan
πŸ“…︎ Jan 03 2022
🚨︎ report
I had a vasectomy because I didn’t want any kids.

When I got home, they were still there.

πŸ‘︎ 10k
πŸ’¬︎
πŸ‘€︎ u/demotrek
πŸ“…︎ Jan 13 2022
🚨︎ report

Please note that this site uses cookies to personalise content and adverts, to provide social media features, and to analyse web traffic. Click here for more information.