A list of puns related to "List of drugs known for off label use"
This will save precious time, as well as provide complete and unambiguous information. I've been doing this for a number of family members and the first responders always appreciate the information.
From the Position Statement Summer 2019:
> The significant lack of evidence for treatments and interventions which may be offered to people with dysphoria is a major issue facing this area of healthcare. There are also differences in the types and stages of treatment for patients with gender dysphoria depending on their age or stage of life. Gonadorelin (GnRH) analogues are one of the main types of treatment for young people with gender dysphoria. These have long been used to treat young children who start puberty too early, however less is known about their long-term safety in transgender adolescents. [...]
And here are the explanations NHS GPs will use not to prescribe HRT or do blood tests coming from private GICs (GenderGP, GenerCare, London Transgender Clinic, etc.).
In their statement, there are no mentions about private (GIC) providers shared care agreement, despite being a know stopgap for patients with the money to pay for private diagnosis. ... If anybody was wondering why your NHS GP won't do shared care agreement (HRT prescription and blood tests) based on your private GIC diagnosis and treatment plan.
The RCGP position statement also explains why NHS GPs won't follow GMC bridging prescription guidelines to minimise harm.
> [GMC] advice fails to address the ethical and safety issues around prescribing outside the limits of oneβs competence, the significant medicolegal implications this carries and the non pharmacological needs of patients as they await access to a specialist.
> Further, the GMC advice above conflicts with their Good Medical Practice ethical guidance which states that GPs must recognise and work within the limits of their competence. As such, GPs face conflicting messages about how to approach advising and prescribing for these patients, which poses a significant risk to GPs in their practice, and patient safety. GPs are ultimately responsible for their prescribing and should not be pressured into prescribing where they feel it is unsafe or involves unacceptable risks. The GMC advice needs review and clarification.
> [...] GPs should not be expected to fill the gaps in commissioned gender identity specialists and clinics. [...] there should no expectation for GPs to advise patients outside the remit of their role as expert generalist,
Edi
... keep reading on reddit β‘People who are paid in cash for legal or illegal work will not get a stimulus check.
Day laborers in construction or ag, doing work for cash - they are probably 100% out of a job right now (in most states), and won't get a stimulus check.
People involved in criminal enterprises as their main source of income - they are probably shit out of luck too.
So, what all categories of jobs (or other attempts to get money) does this [the general shutdown, and the lack of any funding coming their way] impact? Can you think of any to add to the ones I listed in the title?
>The nature of this PTSD pharmacotherapy crisis is three-fold. > > >First, there are only two medications currently approved for the treatment of PTSD by the U.S. Food and Drug Administration (FDA), sertraline (Zoloft) and paroxetine (Paxil).These medications are helpful but are believed to work via the same mechanism of action, and both produce reduction in symptom severity rather than remission of PTSD symptoms. This efficacy gap may be particularly great for patients treated in VA settings. > >Second, the limited efficacy of the FDA-approved treatments for PTSD has necessitated poly-pharmacy for the vast majority of patients treated. These off-label medications, as monotherapy or in combination with other medications, have not been studied adequately for the treatment of PTSD. Therefore, most patients are treated with medications or combinations for which there is little empirical guidance regarding benefits and risks. > >Third, research and development of new medications for the treatment of PTSD has stalled and there is a void in new drug development. There has not been a medication approved for the treatment of PTSD since 2001, despite the significant need. In a survey ofClinicalTrials.gov, there were few pharmaceutical industry-sponsored clinical trials for PTSD that have enrolled patients since 2006: one Phase III clinical trial, four Phase II clinical trials, and no Phase I clinical trials (see The Limited ResearchPortfolio, below). There is no doubt that there is a deficient pipeline of new PTSD medications and it is uncertain about how to best identify new targets for medication development.Even if there were a more robust investment in PTSD research, questions would remain regarding the optimal design for these studies.
What will make governments and drug companies take PTSD seriously, and is the focus on drugs that can't be patented (MDMA, Psilocybin) holding back research and funding?
Hello,
I am a freelance investigative journalist working with a team on an article about the trends and harm of antipsychotics (such as Seroquel, Risperdal, Zyprexa, Geodon and Abilify) being prescribed to children and adolescents for off-label uses, such as ADD/ADHD, Anxiety, Autism Spectrum Disorders, Oppositional Defiance Disorder, Sleeping disorders etc. Basically anything besides bipolar and schizophrenia, which are considered FDA approved uses in children over a certain age. These drugs are known to have serious side effects such as significant weight gain, diabetes and gynecomastia, among other things. If you or somebody you know has been impacted by an off-label prescription of one of these drugs when they were under 18, please feel free to contact me, I would love to hear more about the experience. I think this is an important issue that needs more publicity. You can message me here or email me directly at daniellehyams@gmail.com
Thanks,
Danielle
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