Hereditary spherocytosis Puns

I posted earlier this year about having anemia and being a carrier for hemochromatosis with an elevated ferritin (nearly 400).

After waiting months I finally saw the hematologist this week. I’ve had lifelong anemia and my ferritin level has risen steadily the last 20 years. Based on lab tests she suspects I have spherocytosis (my sibling was diagnosed at birth with it and is asymptomatic). I’m curious if anyone here has it as well?

The current plan is to treat the anemia and then they will begin to remove blood. I suspect they will be taking out less than if I was doing a traditional donation due to the anemia.

Of course I would have TWO blood disorders and they would conflict with each other 🙄

(27M) (6'1 ft) (163 lbs)

I have hereditary spherocytosis and i would like to know will there be any risk for me to take the covid-19 vaccine?

UWorld QID 15459

Both cases involve splenic sequestration so what's going on? I'm probably reading too much into an otherwise easy question, but it's killing me to know the answer to my question lol

Am I at a larger risk when it’s comes to COVID 19 with hereditary spherocytosis? I am a 18 year old male and living with hereditary spherocytosis. I had a complete splenectomy when I was 6 and was on penicillin for about 7 years. I’m slowly transitioning into the adult world as I graduated this past spring and I’m concerned on my health risks with COVID 19, am I at enough risk to die from it or simply will it be harder on my body? Usually when I get sick, I don’t see a doctor unless it’s a fever over 100°F and I then need to follow from there usually with an IV. Any help is greatly appreciated, I cannot find any info online and really need some feedback.

Had my spleen removed due to a rare-ish blood disorder, Hereditary Spherocytosis. It has been about a year and a half since the removal via Laparoscopic surgery. A month later, I was put back into the hospital for "intestinal swelling" or "diverticulitis" (which both of my parents have). I literally cried because I thought I had diverticulitis and I wouldn't be able to eat popcorn anymore (my favorite food ever). That wasn't the case, so I suspected there was a tear created in my intestine during surgery and after the swelling went down, it got exposed. Its fun telling people I am missing an organ! AMA! Proof >>> https://i.imgur.com/9PslVz8.jpg

Getting out of the NICU with a presumptive diagnoses of Hereditary Spherocytosis. Does anyone else have a little one with this diagnoses or have this diagnoses themselves? If so, can we talk?

See title

Options are ‘work hypertrophy’ and ‘reticuloendothelial hyperplasia’, among others. Correct answer work hypertrophy. Aren’t these essentially the same though, since its the macrophages that are working overtime to clear the spherocytes that can’t fit through. Anyone know how these two are different in this context?

Excuse the grammar, I am writing this on mobile.. I signed up for the Navy on July 24th I got a call a few days ago from the recruiting office saying that I failed the medical screening because of a Hereditary Spherocytosis diagnosis in 2003ish, I had a Spleenectomy done in 2004, when I was 6, to remove 3 spleens from my abdomen, (typically you have one, but due to my condition I had three, it kept reproducing itself) this surgery usually leaves patients at higher risk for sickness and infection. I am now 20 years old, happy, healthy, and fit weighing 175 lbs, standing at 5’10. Scored a 70 on the ASVAB, and am due to take the DLAB if I can get a waiver. I have no other medical problems and have not had any since the surgery, but I still got denied. My papers were sent to “Big Navy” as chief calls it, to determine if it was waiverable, or non-entertainable.. Military is my only hope for a better life for my wife and daughter, I am also very heavily tattooed, and cannot join any other branch because of my ink.. If it fails big navy, can I just sign up again, or am i screwed? Are there any current sailors with my condition currently serving? How can I prove that I’m perfectly fine in person, even though I look like a medical liability on paper? Any suggestions?

UPDATE: Going to MEPS on the 10th and getting a physical to see if I can get a waiver.

My short bio: Hello! I was born jaundiced very badly and the "chicken lights" were not helping get rid of it. So, after some tests, hyperbilirubenemia and hereditary spherocytosis were listed on my test results. At one week old, I had a full blood transfusion which helped bring the jaundice down. HS runs on my fathers side of the family. He, one of his brothers, one sister and their father all had their spleen removed at an early age because it was about to erupt. I never got to the point of spleen enlargement where it needed to be removed, but after dealing with low hemoglobin (anemia) and low red blood cell counts all of my life, it was time. After working with my primary physician for years trying to get my anemia issues worked out, fatigue, insomnia, etc (I also have Fibromyalgia, or maybe I dont, it might be all HS and anemia related), she said it was time to get that spleen out because you cant keep living life like this. Having no energy, fatigue, sleeplessness, no appetite, etc was and still is taking a BIG toll on my mental health and will hopefully get better after I fully heal from this surgery. I am on day 3 of recovery and things are going alright I guess. Keeping up on fluids, pain medication and taking it easy (plus sleeping a bunch, I haven't slept this well in probably 10 years, I swear to god).

My Proof: Front view of incisions https://i.imgur.com/9PslVz8.jpg Side view https://i.imgur.com/iXREo5S.jpg

Anyone one got any hints on how to raise haemoglobin levels? I have H spherocytosis and lupus !!!!

I have hereditary spherocytosis. I can't stand the jaundice. It has ruined my life and my self-esteem. I haven't made eye contact with another person in 4 years outside of family. I have trouble sleeping on my left side and am tired often. I don't think I'm anemic anymore but do have a slightly enlarged spleen. My bilirubin is 5.1 mg/DL. Do I meet the criteria for a splenectomy? Can I demand one from my doctor?

Edit: Just some clarification on what Hereditary Spherocytosis is. Basically my red blood cells are a spherical shape rather than the bi-concave disk. This means that they often get mistaken in the spleen for damaged or old blood cells, so they are broken down (this is what the spleen does). Meaning that you would often end up with a lot of bilirubin, which is a yellow pigment that comes from the breakdown of red blood cells, when you have too much bilirubin that isn't being excreted as bile or urine you end up becoming jaundice, which is what I had major problems with when I was younger. Also, you can become anemic and can sometimes even need blood transfusions because your body cannot replace the blood cells as fast as it is destroying them. This leaves you weak and can leave you open to infections.

It is a medical condition that causes jhondus (spelling?) which is yellowing of the skin and eyes It also causes an enlarged spleen. What is basically does is make my red blood cells rigid and hard which makes the spleen want to destroy them. Please ask me anythingHospital Wristband from last checkup My parents still have all the records upload them next time I'm there.

Hi:

Ok first of all if the moderators find this post is against the rules of the subreddit, reddit, or feel it is unethical just delete it please.

My professor asked me to do a presentation based in a real case of Hereditary spherocytosis, he doesn't want one from a book, i went to the local hospitals but the disease is very rare and the doctors willing to help me didn't have a case, and most doctors just told me that the clinical records are private (as they should be). I can't just cheat because my professor wants copys or scans of the clinical history, blood panels, etc (with the patient personal data blacked out of course); to prove its a real person

If anyone could help me please i will greatly appreciated it, if you know an online archive, know a case i can look at, research paper with that kind of info, etc. At this point it looks like im totally screwed

thanks in advance

Hello all, I have dominant hereditary spherocytosis, and lately from my personal research I have found that multiple genes can be responsible for this disease. I did 23andme, only to find that they do not test for markers that can cause my disease. Being a curious person in search of answers, how would you suggest I find out which mutation I have, and how this affects my health?

A stray thought just made me remember something I may have read or a doctor said in passing. Does my blood always have the spherical property, or does it only express sometimes?

It doesn't affect me in any way, I'm just curious.

Hey! I have seen a few 1+ year old posts about Hereditary Spherocytosis and most of them were AmA's and people asking them about their spleen removal (and how they felt after).

Well, I most definitely have HS and I was diagnosed with it at the age of ohhh, about 4 days old. I had jaundice really really bad and the "chicken lights" weren't doing the trick, therefore, I had a full blood transfusion at the age of 1 week.

Now that I am older, I have definitely dealt with anemia because of this, but as I age, I am feeling more and more tired, fatigued, etc. I unfortunately also have Fibromyalgia (which those symptoms fall hand in hand with what I am feeling as well). My doctor has told me (and after numerous tests, cortisol levels, rheumatory diseases, the usual iron and vitamin d levels), I came up clear besides low iron and vitamin D. I am "stuck with feeling like this for the rest of my life due to the Fibro and Sphero."

Any idea if Fibro and Sphero could be related to eachother? I know its believed that Fibro is a neuro problem, but they still aren't 100% sure!

A stray thought just made me remember something I may have read or a doctor said in passing. Does my blood always have the spherical property, or does it only express sometimes?

It doesn't affect me in any way, I'm just curious.

I'm a white male in my late 20s, I had my spleen and gall bladder removed at around 10-12 due to complications from the condition, took penicillin daily until I was 18, and since then have been perfectly healthy.

I can't embed images here, so I made a pdf with all text, pictures, and labs. https://www.scribd.com/document/511582218/askdocs-pdf?secret_password=VqmaLuJA0tGw5bGE5xYp It will be much easier to read the whole thing there, with the images embedded, but I will copy the text here.

36F, 5’5, 115 lb, white.  Primary complaint = fingers and toes turning black and rotten (pictures included).

Existing issues = random red cell destruction without cause, random platelet destruction without cause, swellings and rashes (labs and pictures included).  Medications = iron supplement.  Occasional Claritin, Advil, Prednisone.  No medication right now.  No recreational drugs or smoking.  Rare/light alcohol (an occasional drink on holidays or weddings)

1. Rotten Fingers.

My left thumb got a blood blister so I put Neosporin and gauze on it.  The pain became so intense that I went 72 hours without sleep.  I went to urgent care, who removed the bandage.  The thumb was very swollen and the top third was black and crusty.

(picture)

They sent me to the Emergency Room, where they removed the upper half of the thumb.  The pain completely went away, it was just a little sore and itchy.

But a few days later, all the other fingers and 8 of the toes started turning black.

(pictures)

That’s the hand with the original bad thumb.  The pinkie has a blood blister, the index and ring fingers are turning black and crusting at the very top under the nail, and the middle finger is just inky blue/black without any crustiness or blisters.  The left picture was taken a day after the right one.

Right Hand:  no crustiness or blisters.  The fingers are just dark.  The index finger is getting kind of gooey (last picture).

(pictures)

Toes look blacker than fingers but not crusty.  All but the two smallest toes on right foot are turning black.

The ER doctors were very kind but nobody knew why my thumb turned black and rotten.

Now here are all the other weird symptoms and bloodtests that doctors can’t explain.  None of it seemed like a big deal untl fingers started rotting.

2. Rotting Blood

For years my annual bloodwork showed I was anemic.  For example

(picture)

But I had no symptoms of anemia other than feeling cold, so my NP said being anemic was just “my normal” and prescribed an iron supplement.

Two or three times a year, I would get symptoms of extreme exhau

Hi all,

Thanks for reading this. Apparently, between hereditary spherocytosis, hereditary elliptocytosis, and pyruvate kinase deficiency, only pyruvate kinase deficiency may classically present with neonatal hemolytic anemia. In my mind, this implies any/or of the following (reasonably, didn't want to go crazy with the assumptions):

• The RBC morphological deviation in PKD is so severe that it's particularly targeted by the spleen.
• The RBC morphological deviation by some unrelated mechanism causes increased filtration and destruction by the spleen.

I can't find anything in the literature specifically not this question. Would appreciate any input.

I haven't been able to find any real studies on the vaccine in people with an immunocompromised system. I myself have SLE Lupus, Hemolytic Anemia, Hereditary Spherocytosis, and Chronic Kidney Failure Stage 3. I take care of my mother with thyroid cancer and lung cancer, she is undergoing chemotherapy and soon to be radiation. I have to be careful as a healthcare worker to not get exposed at the office and bring anything home as well as exposure while out doing errands. She and I are both hesitant about getting our vaccines even though we probably should.

Does anyone have recommendations? And research I can read?

Hi everybody!

I’ve made cards for the SketchyIM Anemia videos which were not released in the original Sugar deck.

https://drive.google.com/file/d/1pOu0Ad62efiHI4kJ9zpuf78m73EMs5by/view?usp=sharing

1. Total 113 cards pepper style cards
2. Covers newly released Anemia videos 1.2 through 1.8. I really enjoyed these videos! Well made.
3. Disclaimer: This deck excludes most concepts which were already covered in Sketchy Path/Micro. (For example, cards like “What are the symptoms of Malaria” or “What is the inheritance pattern of G6PD deficiency and Hereditary spherocytosis” and “What are the pentad of symptoms for TTP?” are excluded.)
4. On each card, click “show more about this topic” for the sketchy algorithm charts
5. I also made cards for the Lyme disease and Osteomyelitis videos. Check out the compilation thread in the sidebar for that link!

I'm on to my medicine rotation this quarter... who's with me?! Good luck everybody!

-Taco

https://preview.redd.it/dgybbz94ub961.png?width=1486&format=png&auto=webp&s=92884b8217c1f51aa1204856411ad3dd0237d903

Phil

Sudden Lee

Go post NSFW jokes somewhere else. If I can't tell my kids this joke, then it is not a DAD JOKE.

If you feel it's appropriate to share NSFW jokes with your kids, that's on you. But a real, true dad joke should work for anyone's kid.

Mods... If you exist... Please, stop this madness. Rule #6 should simply not allow NSFW or (wtf) NSFL tags. Also, remember that MINORS browse this subreddit too? Why put that in rule #6, then allow NSFW???

Please consider changing rule #6. I love this sub, but the recent influx of NSFW tagged posts that get all the upvotes, just seem wrong when there are good solid DAD jokes being overlooked because of them.

Thank you,

A Dad.

So far nobody has given me a straight answer

I am currently in the hospital. I had a back operation yesterday. The surgical nurse came in my room and started asking questions about my back. She asked me if I had any falls during the last year. I responded just one. It was after summer.

She laughed and said in 20 years of doing this she never was told that joke.

..... Will get a reward.

Because they work on many levels