The rice immune receptor XA21 recognizes a tyrosine-sulfated protein from a Gram-negative bacterium | A component of immunity in rice advances.sciencemag.org/c…
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πŸ‘€︎ u/burtzev
πŸ“…︎ Jul 25 2015
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For people with ADHD, and have no access to stimulants, I may have found a solution

I came across a nootropic, that can give the same effect of stimulants. I have tried it myself. I got the same effects as using vyvanse. Not as strong as vyvanse, 1/3 of the power.

I dont know its effects long term, so be cautious when using it. Try searching the substances individually, so you have a scope of what you are getting into. Try searching them on r/Nootropics

Take it without food, early in the morning. Also don't use alcohol when using this.

The product is called : NeuroLift Balance Capsules, you can find it here. It's 20 dollars.

Ingredients in the capsule:

Agmatine Sulfate 300 mg

DL-Phenylalanine 250 mg

Tyrosine 150 mg

N-Acetyl L-Tyrosine 150 mg

L-Tryptophan 120 mg

Triacetyluridine (TAU) 50 mg

I found the Nootropic from this guy: https://www.reddit.com/r/Nootropics/comments/opzgri/comment/h6c1vz8/?utm_source=share&utm_medium=web2x&context=3

Western_Floor_3945

>For more natural options, I was experimenting for years with different amounts of tyrosine, N acetyl tyrosine, choline, agmatine sulfate, and small amounts of tryptophan. Was having great results in terms of task switching, attention control and clarity, but it was a pain to measure so many powders every day. I switched over to LiftMode's Neurolift capsules which contain all of these ingredients in almost the same ratio I was taking them. Honestly it had been pretty life-changing. I find that you need to take them on an empty stomach though or they don't seem to work. Only about 3 out of 5 days I take them I get a pronounced effect, but it also seems to have a positive effect on mood and emotional regulation if I take them consistently. I remember in the first week I took them, I was taking a break between tasks, and I stood on my apartment balcony and just watched cars go by and thought, wow, I am in full control of where I put my attention, fully capable of just stopping and being present in the moment, calming my brain and telling it that this was break time, and it was okay to just switch off for a moment. Then I went back to work and didn't need to kick myself or struggle to get started again. Compare this to a normal day where I have to avoid taking breaks at all because if I do,

... keep reading on reddit ➑

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πŸ‘€︎ u/Quiet_Kale_471
πŸ“…︎ Dec 24 2021
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Hangover Prevention Formulation I made - costs about 70 cents for you to make yourself at home

Howdy,

I mentioned this formula in a couple of comments on other posts and figured this would probably be the best way to share with everyone. Also posted this on the supplements sub.

First things first. Here's the formulation...

Ingredient Dose (mg) Notes
Acetyl-L-Carnitine (ALCAR) 1000
Agmatine Sulfate (AS) 1000
Trimethylglycine 1000 Betaine Anhydrous, not Betaine HCl
Curcumin 1000 Phytosome preferred
Dihydromyricetin (DHM) 1000 Beta-cyclodextrin complex preferred
Milk Thistle 500 Phytosome preferred
Boswellia 500 Phytosome preferred
Glycine 1000
L-Theanine 200
N-AcetylCysteine (NAC) 1000 Can also use L-Cysteine / N-acetylcysteine amide
Taurine 500
Nicotinamide Mononucleotide (NMN) 500
Tyrosine 500

Next, I apologize in advance for the weird formatting. Shit saved differently than I had it, and it's like dealing with old school Microsoft word. Painful.

Now then, this formulation can be taken before or after drinking. NAC had one study showing that it increased damage to the liver if taken after intoxication. It was in one study. Literally one, and not a very good / complete one at that. However, I'm not a fucking doctor, so make your own informed choices. I can send the research papers I used for NAC specifically, as well. I have taken this formulation before drinking and after drinking, and it works incredibly well. It has also worked incredibly well for the friends I have shared it with. Literally, every single person has told me this has dramatically reduced their hangovers mentally and physically. From my testing, this formulation is good for about 6 to 8 drinks for a 180lb male. You may have to experiment to get your dosing right for your own body.

This is a conglomeration of interviews I took from folks who tried it. When taken before drinking, you may notice that you do not get drunk in the same way as you would expect. For starters, you hardly notice the physical effects. You feel the buzz you get after the first drink or two, and it stays with you for the night. You just feel very calm and in control of yourself, more social and outgoing. Just comfortable. You also don't 'need' a drink in your hand at all times. The anxiety to have another is not nearly as strong.

If taken after, you can toss this in your mouth and wash it down with your beverage of choice. If using the phytosome and betacyclodextrin complexes, the mixture will be relatively water soluble. I threw it in a workout mixer thi

... keep reading on reddit ➑

πŸ‘︎ 541
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πŸ‘€︎ u/BurkeAbroad
πŸ“…︎ Jul 24 2021
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Need to cycle these or not?

I take the following (been on these for between 2 weeks and 2 months depending on the supplement):

L-Theanine - 250mg 1x daily AM

N-Acetyl L-Tyrosine - 350mg 1x daily AM

Agmatine Sulfate - 250 mg 2x daily AM/PM

Magnesium Glycinate 800 mg 1x daily PM

Phenibut 250-500mg 1x-4x day (only occasionally...never more than twice a week)

Excluding the Phenibut which I am aware needs to be cycled and used in moderation, are the other ones ok to continue taking daily? Or should I be cycling some of those? TIA!

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πŸ‘€︎ u/hoteldopamine
πŸ“…︎ Dec 02 2021
🚨︎ report
SERIOUS: This subreddit needs to understand what a "dad joke" really means.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

πŸ‘︎ 17k
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πŸ‘€︎ u/anywhereiroa
πŸ“…︎ Jan 15 2022
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How To Stop Restless Legs From Opiate Withdrawal

Note: I am not a medical professional.

Restless Leg Syndrome is a neurological disorder characterized by the overwhelming urge to move your body to stop painful or weird sensations. Restless Leg Syndrome usually affects the legs, though some people get symptoms in their arms, torso or head. There have even been reports of people with RLS in phantom limbs.

RLS symptoms can manifest in the following ways:

  • Pain and/or aching in muscles
  • An itchy feeling that cannot be relieved by scratching
  • A β€œcrawly” feeling
  • A feeling of being tickled

There are two types of RLS:

  • Idiopathic – This is a primary condition without a known cause or cure.
  • Secondary – Can be caused by many different things including side-effects from a medication or medical conditions such as Parkinson’s disease, opiate withdrawal and more.

Restless Leg Syndrome from opiate withdrawal will be the focus of this article. One of the symptoms of opiate withdrawal is jumpy legs, twitchy legs, dancing legs, or restless legs…. whatever you prefer to call it. It is different than traditional RLS because the cause of it is known (opiate withdrawal), and there is a cure (time) because it goes away on its own after a few days or weeks. There are many awesome strategies for stopping opiate withdrawal restless legs.

If you really want to know what helps RLS during opiate withdrawal, you’ve come to the right place. My simple and effective 4-Step Plan can stop restless legs from aching, tickling, twitching, crawling, and break-dancing across the room. Furthermore, this natural plan is so powerful that it doesn’t just stop restless legs…it can also work extremely well for reducing insomnia, pain, fatigue, depression, anxiety, sweating, hot and cold flashes, gastrointestinal upset and lack of appetite.

Step 1: Exercise and Stretch

One of the most powerful strategies for treating opiate withdrawal restless legs is to exercise. Walking, cycling and swimming have all been shown in studies to reduce RLS symptoms. Exercise at a moderate pace and don’t over exert yourself. You can walk or cycle on the street, or on a treadmill and stationary bike.

Note: Morning, afternoon and evening are all excellent times to exercise, just don’t perform strenuous exercise within 1-2 hours before going to bed as this has been shown to worsen Restless Leg Syndrome.

**After you get done exercising,Β make sure to use the following leg stretches

... keep reading on reddit ➑

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πŸ‘€︎ u/Frenchkiwi
πŸ“…︎ Oct 26 2021
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Blind Girl Here. Give Me Your Best Blind Jokes!

Do your worst!

πŸ‘︎ 5k
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πŸ‘€︎ u/Leckzsluthor
πŸ“…︎ Jan 02 2022
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This subreddit is 10 years old now.

I'm surprised it hasn't decade.

πŸ‘︎ 14k
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πŸ‘€︎ u/frexyincdude
πŸ“…︎ Jan 14 2022
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Dropped my best ever dad joke & no one was around to hear it

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies πŸ˜‚

πŸ‘︎ 20k
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πŸ‘€︎ u/Vegetable-Acadia
πŸ“…︎ Jan 11 2022
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What starts with a W and ends with a T

It really does, I swear!

πŸ‘︎ 6k
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πŸ‘€︎ u/PsychedeIic_Sheep
πŸ“…︎ Jan 13 2022
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Why did Karen press Ctrl+Shift+Delete?

Because she wanted to see the task manager.

πŸ‘︎ 11k
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πŸ‘€︎ u/Eoussama
πŸ“…︎ Jan 17 2022
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What is a a bisexual person doing when they’re not dating anybody?

They’re on standbi

πŸ‘︎ 11k
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πŸ‘€︎ u/Toby-the-Cactus
πŸ“…︎ Jan 12 2022
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Geddit? No? Only me?
πŸ‘︎ 6k
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πŸ‘€︎ u/shampy311
πŸ“…︎ Dec 28 2021
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I wanna hear your best airplane puns.

Pilot on me!!

πŸ‘︎ 3k
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πŸ‘€︎ u/Paulie_Felice
πŸ“…︎ Jan 07 2022
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E or ß?
πŸ‘︎ 9k
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πŸ‘€︎ u/Amazekam
πŸ“…︎ Jan 03 2022
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What did Spartacus say when the lion ate his wife?

Nothing, he was gladiator.

πŸ‘︎ 9k
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πŸ‘€︎ u/rj104
πŸ“…︎ Jan 15 2022
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Pun intended.
πŸ‘︎ 5k
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πŸ‘€︎ u/Sharmaji1301
πŸ“…︎ Jan 15 2022
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No spoilers
πŸ‘︎ 9k
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πŸ‘€︎ u/Onfour
πŸ“…︎ Jan 06 2022
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Covid problems
πŸ‘︎ 7k
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πŸ‘€︎ u/theincrediblebou
πŸ“…︎ Jan 12 2022
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What is the scariest tree?

BamBOO!

πŸ‘︎ 4k
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πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
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These aren't dad jokes...

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

πŸ‘︎ 12k
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πŸ‘€︎ u/Lance986
πŸ“…︎ Dec 15 2021
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I had a vasectomy because I didn’t want any kids.

When I got home, they were still there.

πŸ‘︎ 10k
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πŸ‘€︎ u/demotrek
πŸ“…︎ Jan 13 2022
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What did 0 say to 8 ?

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

πŸ‘︎ 9k
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πŸ‘€︎ u/designjeevan
πŸ“…︎ Jan 03 2022
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Spi__
πŸ‘︎ 6k
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πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 11 2022
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I dislike karma whores who make posts that imply it's their cake day, simply for upvotes.

I won't be doing that today!

πŸ‘︎ 15k
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πŸ‘€︎ u/djcarves
πŸ“…︎ Dec 27 2021
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The Ancient Romans II
πŸ‘︎ 6k
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Dec 29 2021
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Where do you find a cow with no legs?

Where ever you left it πŸ€·β€β™€οΈπŸ€­

πŸ‘︎ 3k
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πŸ‘€︎ u/kitkatty0309
πŸ“…︎ Jan 16 2022
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I'd like to dedicate this joke to my wisdom teeth.

[Removed]

πŸ‘︎ 7k
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πŸ‘€︎ u/ThoughtPumP
πŸ“…︎ Jan 14 2022
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I did it, I finally did it. After 4 years and 92 days I went from being a father, to a dad.

This morning, my 4 year old daughter.

Daughter: I'm hungry

Me: nerves building, smile widening

Me: Hi hungry, I'm dad.

She had no idea what was going on but I finally did it.

Thank you all for listening.

πŸ‘︎ 17k
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πŸ‘€︎ u/Sk2ec
πŸ“…︎ Jan 01 2022
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It this sub dead?

There hasn't been a post all year!

πŸ‘︎ 13k
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πŸ‘€︎ u/TheTreelo
πŸ“…︎ Jan 01 2022
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How do you stop Canadian bacon from curling in your frying pan?

You take away their little brooms

πŸ‘︎ 6k
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πŸ‘€︎ u/Majorpain2006
πŸ“…︎ Jan 09 2022
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School Was Clothed
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πŸ‘€︎ u/Kennydoe
πŸ“…︎ Jan 08 2022
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Remember that joke I told you about the chiropractor?

It was about a weak back.

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πŸ‘€︎ u/tanglwyst
πŸ“…︎ Jan 16 2022
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Naan-negotiable
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πŸ‘€︎ u/sjmaeff
πŸ“…︎ Jan 16 2022
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Letting loose with these puns
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πŸ“…︎ Jan 13 2022
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Couch potato
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πŸ“…︎ Dec 31 2021
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Baka!
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πŸ‘€︎ u/ridi86
πŸ“…︎ Jan 09 2022
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All dad jokes are bad and here’s why

Why

πŸ‘︎ 7k
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πŸ‘€︎ u/LordCinko
πŸ“…︎ Jan 13 2022
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concrete πŸ—Ώ
πŸ‘︎ 5k
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πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 07 2022
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My name is ABCDEFGHIJKMNOPQRSTUVWXYZ

It’s pronounced β€œNoel.”

πŸ‘︎ 14k
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πŸ‘€︎ u/beef_fried_rice
πŸ“…︎ Dec 25 2021
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For Gotham
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πŸ‘€︎ u/FreeHugsXD
πŸ“…︎ Jan 17 2022
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Why are people so surprised and angry about Djokovic being an anti-vaxxer?

After all his first name is No-vac

πŸ‘︎ 4k
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πŸ‘€︎ u/hangryman23
πŸ“…︎ Jan 06 2022
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If Korean pop is shortened to Kpop and Korean Drama is Kdrama...

What, then, is Chinese rap?

Edit:

Notable mentions from the comments:

  • Spanish/Swedish/Swiss/Serbian hits

  • French/Finnish art

  • Country/Canadian rap

  • Chinese/Country/Canadian rock

  • Turkish/Tunisian/Taiwanese rap

πŸ‘︎ 3k
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πŸ‘€︎ u/hootanahalf
πŸ“…︎ Jan 09 2022
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Knowledgeable man
πŸ‘︎ 3k
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πŸ‘€︎ u/elisioth4739
πŸ“…︎ Jan 16 2022
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That’s Michelle
πŸ‘︎ 5k
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πŸ‘€︎ u/FLEXSEALBREAKER
πŸ“…︎ Jan 10 2022
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Is this sub still active?

There hasn't been a single post this year!

(Happy 2022 from New Zealand)

πŸ‘︎ 10k
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πŸ‘€︎ u/DonStimpo
πŸ“…︎ Dec 31 2021
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What did the ocean say to the beach?

Nothing, it just waved

πŸ‘︎ 2k
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πŸ‘€︎ u/hackerboi1198
πŸ“…︎ Jan 13 2022
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is Isn't
πŸ‘︎ 2k
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Jan 11 2022
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Hangover Preventative Formula - costs about 70 cents for you to make yourself

Howdy,

I mentioned this formula in a couple of comments on other posts and figured this would probably be the best way to share with everyone.

First things first. Here's the formulation...

Ingredient Dose (mg) Notes
Acetyl-L-Carnitine (ALCAR) 1000
Agmatine Sulfate (AS) 1000
Trimethylglycine 1000 Betaine Anhydrous, not Betaine HCl
Curcumin 1000 Phytosome preferred
Dihydromyricetin (DHM) 1000 Beta-cyclodextrin complex preferred
Milk Thistle 500 Phytosome preferred
Boswellia 500 Phytosome preferred
Glycine 1000
L-Theanine 200
N-AcetylCysteine (NAC) 1000 Can also use L-Cysteine / N-acetylcysteine amide
Taurine 500
Nicotinamide Mononucleotide (NMN) 500
Tyrosine 500

Next, I apologize in advance for the weird formatting. Shit saved differently than I had it, and it's like dealing with old school Microsoft word. Painful.

Now then, this formulation can be taken before or after drinking. NAC had one study showing that it increased damage to the liver if taken after intoxication. It was in one study. Literally one, and not a very good / complete one at that. However, I'm not a fucking doctor, so make your own informed choices. I can send the research papers I used for NAC specifically, as well. I have taken this formulation before drinking and after drinking, and it works incredibly well. It has also worked incredibly well for the friends I have shared it with. Literally, every single person has told me this has dramatically reduced their hangovers mentally and physically. From my testing, this formulation is good for about 6 to 8 drinks for a 180lb male. You may have to experiment to get your dosing right for your own body.

This is a conglomeration of interviews I took from folks who tried it. When taken before drinking, you may notice that you do not get drunk in the same way as you would expect. For starters, you hardly notice the physical effects. You feel the buzz you get after the first drink or two, and it stays with you for the night. You just feel very calm and in control of yourself, more social and outgoing. Just comfortable. You also don't 'need' a drink in your hand at all times. The anxiety to have another is not nearly as strong.

If taken after, you can toss this in your mouth and wash it down with your beverage of choice. If using the phytosome and betacyclodextrin complexes, the mixture will be relatively water soluble. I threw it in a workout mixer thing with water and downed it. The taste isn

... keep reading on reddit ➑

πŸ‘︎ 286
πŸ’¬︎
πŸ‘€︎ u/BurkeAbroad
πŸ“…︎ Jul 24 2021
🚨︎ report

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