Off Label Use Puns

Any tips are appreciated

For example:

Staff of Flowers can grow pot.

Bag of Holding makes for a great sleeping bag. No need for a tent, just cover your head with a shield or a hat.

Immovable Rod can be used to hang a hammock if there's no two trees the appropriate distance apart.

Hi All!

P4 Student here! I have to give a presentation in regards to some off - label uses of medications.

I was wondering what are some interesting ones to talk about?

Some that I've seen and come to my mind...

Prazosin - Night Terrors

Clonidine - Opioid Withdrawal

Levothyroxine - Deceased Organ Donor Management

Spironolactone - Acne

Thanks!

Dumbbell -> toe-toughener

Every time I mention my insomnia to my psychiatrist they recommend seroquel for a sleep aid bc trazadone didn’t work for me, but after doing research it appears it’s not approved for this use. I also know many people who are prescribed it for this reason (4 others that I know in real life, I asked people on a mental health forum and there was an overwhelming amount of people with the same story)

I understand that it might be a quick fix but Seroquel’s pharmacology it’s pretty bad and from what I’ve read can cause Parkinson’s because of how it effects the dopamine receptors.

I think my concern might be An overreaction but I’m very curious.

Hello,

I am a freelance investigative journalist working with a team on an article about the trends and harm of antipsychotics (such as Seroquel, Risperdal, Zyprexa, Geodon and Abilify) being prescribed to children and adolescents for off-label uses, such as ADD/ADHD, Anxiety, Autism Spectrum Disorders, Oppositional Defiance Disorder, Sleeping disorders etc. Basically anything besides bipolar and schizophrenia, which are considered FDA approved uses in children over a certain age. These drugs are known to have serious side effects such as significant weight gain, diabetes and gynecomastia, among other things. If you or somebody you know has been impacted by an off-label prescription of one of these drugs when they were under 18, please feel free to contact me, I would love to hear more about the experience. I think this is an important issue that needs more publicity. You can message me here or email me directly at daniellehyams@gmail.com

Thanks,

Danielle

Hi there, A couple months back I learned about a "in-person" ebay-like place in the Cincinnati area called fast tracks. Basically it appears to be a place where used or roughly returned products end up when they cant go back on shelves, but there are also new items there as well, it's an interesting business.

ANYWAYS, the topic at hand.

So I have 1000ft of cat 6 wire for about half the price of 5e. I have more than I need for running ethernet around the house and a few projects that might be able to use this wire. The house my wife and I bought recently has two broken doorbells, I imagine they run on 12, 18, or 24volts. Would the strands within the doorbells be capable of safely/reasonably filling out the role of replacement?

I would get the 10mg and cut it in half.

To make a long story short I was diagnosed with Chronic Recurrent Abdominal Pain (CRAP) at the age of 12. It is a combination of Chronic Abdominal Pain (CAP) and Recurrent Abdominal Pain (RAP) so I get a fun acronym.

The diagnosis took a very long time, dozens of tests, specialists, and appointments. Eventually I ended up in the Diagnostic Referral department of the Children's Hospital of Pittsburgh with the best doctor I have ever and probably will ever have had. This department is where they send the cases that are complex or no one can figure out. My doctor not only diagnosed me but was committed to finding a successful treatment. At this point I don't remember what all we tried but eventually she prescribed Lexapro. She explained that it was typically used to treat anxiety and depression but there had been some success using it off-label for chronic pain management. The leading theory with CRAP is that the nerve endings in my abdomen (upper abdomen to be specific about where my pain was/is) are misfiring and sending pain signals to my brain when there is no reason.

I started on 10mg with some success and eventually we worked up to 30mg and that seemed to alleviate a majority of my pain. I have been on that dosage for just over 15 years.

I was officially discharged when I turned 21 and eventually moved to a local doctor that was comfortable just renewing my prescription to maintain my condition. I'd like to say the first doctor was fine but... she refused to renew my prescription in a timely fashion one time due to some inane office rule so I went through a hellish withdrawal period. The next doctor I tried had NO idea what was going on and referred me to the psychiatry part of the practice. The psychiatrist saw me for a bit but was honest with me telling me there was no reason for him to continue seeing me so he helped me pick another doctor from the practice that was comfortable treating me. This new doctor has been the best so far. He has no problem continuing my prescription, a semi-understanding of my condition, and no desire to mess with what is working. Over the years doctors have tried lowering the dosage but my pain returned. I'm about due for another try. I'd like to get to a lower maintenance dosage but if 30mg is the magic number, I'll live with it.

I just thought I'd share my atypical experience with Lexapro and see if anyone has had a similar experience.

From the Position Statement Summer 2019:

> The significant lack of evidence for treatments and interventions which may be offered to people with dysphoria is a major issue facing this area of healthcare. There are also differences in the types and stages of treatment for patients with gender dysphoria depending on their age or stage of life. Gonadorelin (GnRH) analogues are one of the main types of treatment for young people with gender dysphoria. These have long been used to treat young children who start puberty too early, however less is known about their long-term safety in transgender adolescents. [...]

And here are the explanations NHS GPs will use not to prescribe HRT or do blood tests coming from private GICs (GenderGP, GenerCare, London Transgender Clinic, etc.).

In their statement, there are no mentions about private (GIC) providers shared care agreement, despite being a know stopgap for patients with the money to pay for private diagnosis. ... If anybody was wondering why your NHS GP won't do shared care agreement (HRT prescription and blood tests) based on your private GIC diagnosis and treatment plan.

The RCGP position statement also explains why NHS GPs won't follow GMC bridging prescription guidelines to minimise harm.

> [GMC] advice fails to address the ethical and safety issues around prescribing outside the limits of one’s competence, the significant medicolegal implications this carries and the non pharmacological needs of patients as they await access to a specialist.

> Further, the GMC advice above conflicts with their Good Medical Practice ethical guidance which states that GPs must recognise and work within the limits of their competence. As such, GPs face conflicting messages about how to approach advising and prescribing for these patients, which poses a significant risk to GPs in their practice, and patient safety. GPs are ultimately responsible for their prescribing and should not be pressured into prescribing where they feel it is unsafe or involves unacceptable risks. The GMC advice needs review and clarification.

> [...] GPs should not be expected to fill the gaps in commissioned gender identity specialists and clinics. [...] there should no expectation for GPs to advise patients outside the remit of their role as expert generalist,

Edi

DH comes to me bemoaning an objectionable pimple and requests my help. Angels sing and my heart leaps for joy like a fawn through a blossoming meadow; of course, I say! I provide the Holy Stridex, declaring that the main ingredient is an inflammatory--"Like aspirin," I helpfully suggest.

DH also suffers from tendonitis, being a daily pianist. Lo and behold, a few days post I find him anointing his forearms with the Holy Stridex. He happily informs me that a miracle has occurred! It doth quell the pain! All praise the Holy Stridex!

And now DH has his own container marked "Mr. anonymousnine. Do Not Touch" which he totes around with him to various performances and other musical goings-on.

Theres a patient that comes in who is very skinny and fills phentermine 37.5 mg every 45 days or so(I looked at the profile today when I was typing in the script and noticed thats about how often shes been filling it. Sometimes every 30 days). She has been on this medication for as far back as I can see in the system so like over 2 years. I thought it was only supposed to be used for short term.

And yes it is definitely for her, shes not dropping it off for someone else. She is in her 20's. Pharmacist never noticed because I'm always the one typing it at drop off. I am pretty sure but not certain that the diagnosis code literally says OVERWEIGHT and she is not remotely overweight. She is probably 115 lbs 5'7 if I had to guess. I don't feel comfortable filling a medication for someone who is likely anorexic and abusing it, unless there are off label uses for phentermine that I don't know about? I pointed it out to the pharmacist today for the first time but she was already gone so he couldn't look at her. Pharmacists, what would you guys do in this situation?

Edit: Pharmacist saw patient today when she came to pick up meds and saw how skinny she was. He told her he had to call her physician to clarify something on the script. Patient calmly waits and the doctor says something like "I wrote it for a legitimate medical purpose. I hope you aren't accusing me of being some kind of pill mill. I care about my patients. I have been treating this girl since she was a teenager, I know her medical history. This patient is on a lot of medications that cause weight gain and gains 20 lbs a month when she's skipped it so he has no choice but to keep prescribing" that's all paraphrased but what I do remember the pharmacist saying word for word "she gets deeply depressed if she doesn't look attractive and I'd rather have her skinny than depressed". Wow.

We ultimately still sold her the script.

I will start with botox for over active bladder.

I was experimenting today with some of my car detailing products. I used Meguiar's PlastX to remove scratches and oxidation from a 1970s Seiko watch with an acrylic crystal. I used the the same product to remove a lot of tarnish from the stainless steel. I then used OptiSeal on my Seiko SKX007 dive watch, which added some gloss and cleaned it. I'm curious if the gloss will last. I then tried some Poorboy's wax on an old pair of leather boots I had. The wax definitely added a shine and water beading to the leather. I'd say all of this was success, but I'll keep everyone posted in a few days if I end up shoeless and with discarded watches. I'm curious to other off label uses others have found for car detailing products. I'm going to try 303 protectant on my soles, and perhaps their outdoor fabric spray as a waterproofer for nylon & synthetic shoes and my down jackets.

I have this card for my ventilation system. In it there's this code for the label:

  label: >-
    [[[
        if (entity.state =='off') {
          return variables.ulm_off;
        } else if (entity.state =='dry') {
          return variables.custom_card_tpx01_aircondition_dry;
        } else if (entity.state =='heat') {
          return variables.custom_card_tpx01_aircondition_heat;
        } else if (entity.state =='heat_cool') {
          return variables.custom_card_tpx01_aircondition_heat_cool;
        } else if (entity.state =='cool') {
          return variables.custom_card_tpx01_aircondition_cool;
        } else if (entity.state =='fan_only') {
          return variables.custom_card_tpx01_aircondition_fan_only;
        }
        return entity.state;
    ]]]

But I have a seperate sensor that tells the state of the ventilation. High, normal or away - sensor.vtr_status. Is there a way I can have the label tell me that state instead?

I've made a Thai tea Panna Cotta and a green tea Panna Cotta and both were delicious. I've also made a blueberry and Earl Grey infused liqueur (which is delicious, but a bit of a punch in the face).

Up next, I'm going to take a day and try to make some Hojicha infused dark chocolate truffles.

What are some of your favorite tea flavored things, tea experiments, or tea infused failures?

So I have a small business where contributors send in their art, writing, photography, etc. and I use it to design a monthly magazine. The magazines are very small and lightweight. I've always shipped it in a 9 x 12 regular paper envelope with a small piece of cardboard inside to prevent the magazine from bending. I always ask to ship it as cheap as possible (no tracking, etc.) and they send it as a large envelope (regular first class mail) for ~$1.88/package. All of a sudden, after a full year of doing it this way, every employee at every post office near me (I've gone to so many different ones) tells me it has to be sent as a package/parcel, which costs about $4.50/package. That's more than it costs just to make the magazine!! Supposedly, nothing has changed and they should have always been charging me this much, but I've gotten that price at SOOO many different post offices in a few different areas (I moved this year so it's not like I was always sending from the same city and getting that lower price), that I can't see that being the truth.

Anyways, it seems sending it as a large envelope for under $2 is no longer an option at the post office. I tried using different sites that allow you to print labels online and just drop it off at the post office, but the cheapest I could get it down to using that method was $3.40.

I read somewhere that you can use 2 stamps for a 1 oz large envelope, and add an additional stamp for each extra ounce. I have to weigh it to be sure, but I believe my packages are usually about 3 oz, so my question is, can I get away with putting 4 stamps on each envelope and sticking them in the mailbox? That way it would only cost me $2/envelope.

I'm not necessarily trying to cheat the system, it just doesn't make sense to me why it needs to be sent as a package when it is literally inside a "large envelope"??? I asked one post office employee why it couldn't be sent as a large envelope and she said because they're not able to bend it, even though the cardboard inside is pretty small and thin. But I believe the magazines will get damaged without the cardboard. I considered the rigid, non-bendable mailers, but those would have the same issue I think, because they cannot be bent.

-_-

We live in a Corporate prison planet. Make no mistake about it. But Who controls Pfizer if this corporation that was sued by thousands of people for selling bad pharmaceutical drugs, but yet still wins a contract to rush and produce this coronavirus vaccine? And make millions. I've heard 3 investment companies that own the majority shares of almost every major corporation in America. Black Rock, Vanguard and State street. Regardless who ever controls this corrupt company have overwhelming power over governments. And we are forced to take a shot from this corrupt diabolical company.

This article is about the Pfizer law suit and pay off. From a mainstream media article from 2009. Now these mainstream media outlets are silent on this information and pushing the pfizer vaccine https://abcnews.go.com/Business/pfizer-fined-23-billion-illegal-marketing-off-label/story?id=8477617

Here is the news report from Indian news channel Gravitas: Reveals How Pfizer blackmails countries for shots https://www.youtube.com/watch?v=nYIJxoh7gqw&t=167s

I'm pretty sure most of you have seen this. Brought to you by Pfizer. How this company also advertises and blackmails mainstream media. https://www.youtube.com/watch?v=XlL5_kKyLA0

And for more on Covid 19 lies and cover ups please check out this website from independent doctors, reporters, whistleblowers and journals https://alternativenewsvideos.com/covid-19

Hello all,

I am a freelance investigative journalist working with a team on an article about the trends and harm of antipsychotics (such as Seroquel, Risperdal, Zyprexa, Geodon and Abilify) being prescribed to children and adolescents for off-label uses, such as ADD/ADHD, Anxiety, Autism Spectrum Disorders, Oppositional Defiance Disorder, Sleeping disorders etc. Basically anything besides bipolar and schizophrenia, which are considered FDA approved uses in children over a certain age. These drugs are known to have serious side effects such as significant weight gain, diabetes and gynecomastia, among other things. If you or somebody you know has been impacted by an off-label prescription of one of these drugs when they were under 18, please feel free to contact me, I would love to hear more about the experience. I think this is an important issue that needs more publicity. You can message me here or email me directly at daniellehyams@gmail.com

Thanks,

Danielle