I started on low dose naltrexone 4 weeks ago. I started at 1.5 MG at night.
My brain fog got increasingly better and now I don't feel any brain fog at all.
I added another 1.5 MG in the morning this week.
I had acute covid March 2020, my long covid is more MCAS-y. I'm also on a low histamine diet, antihistamines, and lots of supplements. I've had ups and downs over the past 20 months. This is the best I've felt.
My Western medicine friendly naturopath is guiding my LDN journey and she has a lot of experience with it. My local long covid clinic is supportive of the LDN too.
I started on a very low dose of .5 mgs and am up to 1mg a day. The target dose is 4.5, but I don’t think I need it as I am pretty much pain free. It has just been about three weeks since I have started and I can’t believe how fantastic I feel, aside from the side effects (upset stomach, dizziness and some confusion) but no pain! The side effects are supposed to be short lived and I am just so excited, I had to share!
what drug did you take? I saw on a post somewhere on here that a frequent wine drinker lost the “buzz” effect of drinking whilst taking LDN. I am 5 days in and noticed the same thing, I didn’t feel any thing after about a glass of wine which was just weird and numb-seeming. well worth the effects of LDN if it works, but I was wondering what other substances you all have taken on LDN and if you noticed any change in the effect it had on you?
Vote your preference/favourite and explain why in the comments
Hello redditors, bit short notice but is anyone interested in going to Egg today, my friend has just backed out so need some other people to boogey with. They will be playing house and techno music and night ends around 6am! So yh if your down lmk, send me a msg, planning to get there around 11-12am. Thanks!
I want to take advantage of this chance we have whilst employees have more hiring opportunities than usual.
I'd like to persue a new career path where I will be paid enough to not worry about reaching FI whilst treating loved ones and having kids.
My current situation is just not cutting it anymore even with a high savings rate. Some jobs are more equal than others...
I'm 25-30 age range but I do have various marketable skills inclusing a 1st class Biology degree and advanced Excel/VBA knowledge.
If you were to start over your career in the current market, what role would you choose in the Tech or Finance sectors to smash those FIRE admirations into reality ?
Please feel free to lend any advice deemed related. Everything is on the table.
I have a stomach issue that apparently LDN can help with as it's a prokinetic. However before I decide to take it I'm trying to find out how it effects libido. Can you share your personal anecdotal experiences pls
I’ve heard that you should start at a very small dose and slowly work your way up, but he has told me that I will be starting 4.5 mg just like that. The instructions on the bottle also say to take this at night. But everything I’ve read has told me the opposite. Is this bad?
Just seeing if there is anyone out there that has experience taking LDN for depression and anxiety? I’ve been on it since October or November. I’m having mixed feeling about it. I’m up to 4mg and felt good for a bit but I’m starting to dip. I’ve tried so many medications even Ketamine and TMS. TMS probably gave me the best results but my mood has since dipped recently after completing treatment in November. I’ve been on lamotrigine also for the last couple of years.
CFS absolutely wrecked my sensory nervous system and it has stayed that way despite remission. Abilify didn’t help in the slightest, and so I’m wondering if it’s even worth going down the route of LDN, or if this is just permanent brain damage and I have to come to terms with it.
Has anyone tried the treatment with so-called LDN treatment with low-dose Naltrexone? I have been seeing this lately more and more popping up from private clinics helping people that suffer with inflammation in their body and seems to work in most cases. Also found an interesting paper about it.
I JUST starting taking LDN for anxiety and depression - and I have heard that one of the side effects can be weight loss. I am THRILLED about this side-effect :-) haha - and hoping it happens to me!
For those who are taking LDN, and have lost weight - is the weight loss due to lower appetite? I just ate a light lunch and feel quite full and satiated. Usually I need chips and bread to make lunch feel like a meal. Is the weight loss due to being able to feel fuller on less food?
Thanks for any info!!
Hi all,
I am relocating from LDN to NYC next month for a job in finance in Manhattan. In the spirit of being super organised, I was wondering if anyone had any tips on what I could bulk buy ahead of time? My company is paying for a load of my stuff to be air shipped so I have the luxury of taking additional items that may be easier / cheaper to source in the UK vs.the US. Also I am very familiar with the good stores here in the UK so if I can, I would rather take some items from these trusted retailers (especially now that there are sales on!!):
These are the things I have learned/noted so for from reading historic posts:
- do not bother bringing electrical, replace them in the US
- bulk buy medication as it’s much harder to source (prescribed)/more expensive in the US
- sanitary items are even more expensive in US so may be worth bulk buying those in the UK ?
- do not take bed linen as bed sizing is different in the UK/US
- buying British teabags and chocolate in bulk (personal taste/preference)
Also one question I had was how strict are customs/the border with regards to shipping goods over across the US border? My shipping company have said things like no food and liquids are allowed to be shipped over but how strict is that rule? Do people tend to do it anyway and not declare it? I only ask in the context of shipping over certain cupboard foods and hair products etc
Please let me know if you think I have missed anything else! Thank you.
Additional information:
- Single
- 24y/o woman
- Will be making ~$175k per year
- No idea on where I’ll be renting, staying in temp accommodation in Manhattan for the first 6 weeks
- My company is paying for 2 x bags on my flight & 500lbs to be shipped via air freight. I am trying to declutter as much as possible and take the absolute minimum/necessary in regards to my clothes but happy to start buying/taking home/ small furnishing items with me. Especially as I have 0 and will be starting / furnishing my apartment in NYC from scratch
Was wondering if LDN and Ketotifen sort of potentiate the results in especially systemic Mcas with cutaneous Mast cell degranulation and cardio vascular symptoms. thanks
Has anyone found any of these effective for flushing from heat? Meeting with my doctor soon and I’d like to persuade him to prescribe me one. Thank you
Hello everyone,
I've had chronic fatigue syndrome for the last few years and I cannot work because the brain fog is so heavy. My doctor told me to try LDN, and after the third night I had a day where I felt completely healed and extremely excited. My theory is that I probably had a massive dopamine/endorphin explosion. Anyway after that experience, LDN is just making me more and more tired. At first it also made me kind of sad/depressed I think but now it's a little better. I'm only on my 10th day of LDN at a very low dose (I went from 0.1 to 0.3 now) so I guess I should stick to it and try for longer, but on the other hand... I'm already very tired without the need for another medication that makes me even more tired. I sleep a lot and I have a very hard time getting out of bed, and I just feel so tired throughout the day. It gets a little better at night.
Has someone already experienced that ? I know that LDN can make some people tired, but do you think I should push through or maybe I should stop it a little ? I'm a little worried that it makes me permanently worse. Since there's so little research on LDN makes you guys my first source of information. :)
Thanks a lot for reading me and please excuse the grammar mistakes, English is not my first language.
I'm thinking about trying LDN but I already have emotional blunting from an antidepressant I took. I've been off all antidepressants for well over a year but this hasn't subsided. I also struggle to enjoy things as much as I used to but I'm not depressed if that makes sense.
How has LDN effected your mood and general pleasure for things in life. Has it blunted emotions like antidepressants or has there been no difference. I'm not do interested if your mood has changed because LDN has helped pain management or improved physical health in turn upping mood. Only about it's direct effects.
Thanks!
Anyone else with dysautonomia (I have POTS, EDS, and MCAS) start taking LDN and see their dysautonomia symptoms flare up? I’ve been feeling super dizzy and more shaky/sweaty, short of breath, just overall more “potsie” and wondered if anyone else experienced this before starting to feel better?!
Edit: I’m on .5mg!
I started long hauling a couple weeks after infection in July of 2020. It's been over a year and my immune system has rekt my body. Mri after mri, pharmaceutical after pharmaceutical and after tens of thousands of dollars and over a year of pain, fatigue and mental anguish I've found some semblance of relief in CBG and Low Dose Naltrexone in combination. I am not a Dr by any means. I have been to several in the last year or so and this was not a recommended treatment but it has made a huge difference in my quality of life. This reddit forum has also been a great place to read about what everyone is going through and feel less alone and misunderstood so when I found something that has helped I felt obligated to share it with you all. Thanks to everyone who has shared their stories and hopefully this helps others as well. For the record, symptoms included; shortness of breath, numbness in limbs, raynaud's syndrome, brain fog, memory loss, joint pain, GERD, depression, derealization, tremors, irregular heart beat, fatigue, stiffness, blurred vision and sleep issues(trouble falling and staying asleep).
I want to get back into Sikhi but I've just been dealing with a lot of feelings of isolation. I want to be around people like me; all I do is work and train in the gym and read books by myself.
feel free to message
hey all, I finally got my prescription delivered by agelessrx, and am started off at 1.5 mg. I am just curious after reading so many posts about how people started at even lower doses (0.1 -0.5), how y’all knew it was too much?
usually I am extremely sensitive to medications so I honestly figured I’d have a reaction of some sort, but I don’t think I’m noticing anything. Given it’s been only two days… should I just carry on with 1.5 mg if I’m feeling fine?
Additional info, I’m using LDN to treat Graves’ disease symptoms. I was diagnosed five years ago so these symptoms could honestly just be so heavy the LDN dose is fine for me.
Hi m, I started 1mg of LDN for anhedonia, I feel very fatigued, and achy, in bouts of mild to severe. As I used to deal with this before, I can't really work out if I've become ill or its the side effects of ldn. Does anyone know if this is common?
Five year daily user 8-25gpd throughout that time. I have been sick and desperate for a long time. My life has been stolen from me! Weight gain, depression, horrible pain in my whole body (I have a lot of injuries/surgeries also), hyperpigmentation on face, quit working out, great career is suffering, socially isolated, high BP, the works!
I started researching Naltrexone and decided to plunge. I took this week off work, and got some Nal from walk in clinic dr. I titrated it down and started with ULDN (essentially drop dosages) every twenty minutes as I could tolerate wd. I started this on Christmas.
Immediately the next day I was in a happy mood and feeling better. Every day has been a little better. I feel really good today, started eating right again, taking probiotics and chlorophyll to start fixing my gut. Day 4 was the worst. I had cravings, but I took more NAL and knew it wouldn’t work. I’m so glad I didn’t use.
I have been increasing by 1/2-1mg (approx) every day and am holding at 4mg now.
HERE is the huge thing…. My cravings (except day 4) are essentially GONE. They will float into my brain, then float out. I’ve been doing things last couple days I havnt done in a LONG time. Guys… I journaled. Geez!
I’ve also drank w K and have drank for ten years. ZERO desire for it now.
WD we’re way tolerable with the LDN. It was a little rough the first 5 days (sweats at night, tired, not much sleep) but getting better. I also am taking: 4000mg liposomal vit c, vitd3, magnesium bisglycinate, epsom baths,lots of water,
This is my longest stretch and I feel really good.
Hi,
Out of curiosity, I tried LDN as I have hear/read great stuff about it. I do not have any immune conditions (e.g. FM, CFS) nor any other major psychiatric or health issue, other than perhaps some occasional tiredness.
Potential goals were potentially greater energy levels, some appetite reduction, a higher hedonic tone at baseline - but I was trying LDN mostly out of curiosity (also bc I am a final year med student and have access to it and I wanted to see what the hype was about).
I got me some liquid naltrexone (50mg/10ml), which I dosed at 0.5mg (0.1ml using an insulin syringe).
On day 1 I took 0.5mg in the evening, got a little tired, but did not think anything of it. That night, using the oura ring, my SWS numbers halved (from usually 2h to just 50min) and my REM-numbers doubled. Again, I did not think much of it.
The next day, I thought I would rather see results fast and decided to take 1mg (0.2ml) in the morning -which is still a very low dose -or at least I thought so. 2-3h later I got massively lethargic. Usually, my energy levels are quite good, but now I could barely keep my eyes open at like 9am. To counter the tiredness, I made some black tea (I usually do not drink much caffeine and caffeine is my "secret weapon"), which did nothing. Weird. I added 50mg of modafinil sublingually, which usually is very strong for me. However, this did not help either.
At around noon, I started to feel "weird". Everything felt "colorless" (very hard to describe). I went for a walk and listened to some music. Usually, I am quite emotional, but now I felt nothing. Later, I had a conversation with a friend about topics that usually get to me emotionally, but again, nothing. Towards the evening, I was incredibly tired (very unlike me) and then a girl I am currently dating spontaneously said she would come over to my place. I have known this girl for only 2 weeks and I immediately crushed and got butterflies and the six or so dates we had, were all subjectively quite intense and beautiful. But yesterday, as she was sitting in front of me, I could not feel any sparkle, which I think she noticed. Then as we were kissing and cuddling, I again felt nothing. This was/is a very scary experience to me and I somehow felt like a psycho/sociopath.
(As a side note, this makes me wonder, whether some people that turn to drugs have their hedonic tone at baseline compared to what mine was on LDN. If this is the case, no wonder people would turn to drugs just
... keep reading on reddit ➡
Has anybody tested trading between the two games using ldn or is that not a thing? Does it have to be the same game?
So it says that RyuLdn uses a p2p system to connect which means offline LAN should work since there are no master servers required.
However, if my PC is not connected to the internet and instead just connected to my real home LAN I get a disconnection error on the game a few seconds after I press "create a game". Why? Is there a secret online service provided by Ryujinx team that it's trying to connect to?
If so may we run the service ourselves if we want to connnect on offline LAN and not over the internet?
Yes I know that actual switch's LAN works with games that support that but I'm trying to play a game that doesn't support LAN but does support local wireless. So why doesn't local wireless using LDN work?
Thanks for any help given :)
