First of its kind study: No serious adverse effects from long-term MMJ use. "No evidence of harmful effects on cognitive function, or blood tests among cannabis consumers and we observed a significant improvement in their levels of pain, symptom distress, mood and quality of life" sciencedaily.com/releases…
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πŸ‘€︎ u/twenafeesh
πŸ“…︎ Sep 29 2015
🚨︎ report
BPA has effects on the developing brain even at doses below current "No Observed Adverse Effect Level" ncbi.nlm.nih.gov/pubmed/2…
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πŸ‘€︎ u/Bill_Nihilist
πŸ“…︎ Aug 30 2016
🚨︎ report
First of its kind study: No serious adverse effects from long-term MMJ use. "No evidence of harmful effects on cognitive function, or blood tests among cannabis consumers and we observed a significant improvement in their levels of pain, symptom distress, mood and quality of life" sciencedaily.com/releases…
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πŸ‘€︎ u/twenafeesh
πŸ“…︎ Sep 29 2015
🚨︎ report
[PH] - No serious adverse effects observed among Sputnik V recipients β€” DOH | Manila Bulletin mb.com.ph/2021/05/29/no-s…
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πŸ“…︎ May 29 2021
🚨︎ report
[PH] - No serious adverse effects observed among Sputnik V recipients β€” DOH mb.com.ph/2021/05/29/no-s…
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πŸ‘€︎ u/AutoNewsAdmin
πŸ“…︎ May 29 2021
🚨︎ report
Feynman says that it's almost without a doubt that uncertainty arises to amplify the effects of single atomic events to such a level that they may be readily observed by large systems. Is he saying that, without uncertainty, there would be no interaction in the universe on a large scale?

Quantum Mechanics and Path Integrals, 2nd edition, page 22

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πŸ‘€︎ u/GenesisStryker
πŸ“…︎ Dec 04 2021
🚨︎ report
Sucralose (Splenda) may have neurotoxic properties: Although no adverse acute toxic effects have been observed in standard tests, significant feeding and behavioural alterations have been reported in non-standard tests using water fleas. This may indicate "possible sublethal effects." ncbi.nlm.nih.gov/pmc/arti…
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πŸ‘€︎ u/axolotl_peyotl
πŸ“…︎ May 12 2014
🚨︎ report
For a foreign vaccine, the first 100 beneficiaries will be observed for week for adverse effects. After that they are approved for wider use.
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πŸ‘€︎ u/eff50
πŸ“…︎ Apr 13 2021
🚨︎ report
Can you link studies that show no adverse effects of 300pg/ml Estradiol and up levels in t women?
  • Hey everyone, first of all I'm really glad to have found this sub, rectal progesterone has been a wonderful addition to my life and also i can tackle my hair loss/hair density loss consciously now - but that's a story for another day!

  • So I'm in Germany and my current provider aims for E2 levels under 200pg/ml (I'm currently at 173pg/ml with 3 pumps of 0,75mg Oestradiol in alternating armpits spread throughout the day). I see that a lot of people here aim for values around 300pg/ml and higher and the consensus is that it's safe - however i want to find something more science-y to show to my doctor. I haven't made an argument for a dosage increase yet so she has do defensive walls up, and i want to compile my point well.

  • Could you guys point me to research that has shown the beneficence and lack of harm(blood clots, cancer yada yada) of estradiol levels this high?

I would LOVE that and be very grateful.

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πŸ‘€︎ u/collisiondamage
πŸ“…︎ Feb 05 2021
🚨︎ report
After 100 days 100% response rate and there were no serious adverse events observed.

In 2018, more than 67,000 drug overdose deaths occurred in the United States14 of which almost 47,000 (70%) were opioid-related. Over 70% of the 70,630 deaths in 2019 involved an opioid.15

β€œWe are anxiously awaiting a new injectable gel formulation of dexamethasone and submission of data to the FDA for the treatment of radicular pain based on the results of a large, randomized, placebo-controlled, multi-center trial. If approved by the FDA, SP-102 would be the first corticosteroid with an indication for epidural administration in the U.S., resulting in rapid pain relief and addressing safety issues with off-label steroid preparations. SP-102 would be a welcome addition to the armamentarium of interventional pain physicians, providing a non-surgical, non-opioid alternative for a condition affecting millions of people,” said Dr. Steven P. Cohen, Chief of Pain Medicine and Professor of Anesthesiology & Critical Care Medicine, Neurology, Physical Medicine & Rehabilitation, and Psychiatry & Behavioral Sciences at the Johns Hopkins School of Medicine, and a Professor of Anesthesiology and Physical Medicine & Rehabilitation at Walter Reed National Military Medical Center, Uniformed Services University of the Health Sciences.

We believe that SP-102 could be the first FDA-approved epidural steroid gel injection product for patients suffering from this common, very painful condition,” said Jaisim Shah, President and Chief Executive Officer of Scilex Holding Company.

https://www.scilexpharma.com/scilex-holding-company-a-sorrento-company-announces-complete-enrollment-on-non-opioid-injectable-sp-102-semdexa-phase-3-pivotal-trial-c-l-e-a-r-program-for-sciatica-pain-management/

PLEASE READ THIS PARAGRAPH AGAIN. READ WHAT THE RESULTS WERE IN THE PHASE 2 TRIAL.

A Phase 2 trial to characterize the pharmacodynamics and safety of repeat dose SP-102 in subjects with lumbosacral radicular pain (sciatica), showed all subjects experienced rapid reduction of leg and back pain following an initial and repeat SP-102 injection treatment, with group median for average pain in the affected leg reduced by over 50% throughout 28 days (100% response rate). The lack of cumulative effect and rapid resolution of hypothalamic-pituitary-adrenal (H

... keep reading on reddit ➑

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πŸ‘€︎ u/MEETMEONLINE
πŸ“…︎ Nov 17 2021
🚨︎ report
General Relativity Withstands Double Pulsar’s Scrutiny. Sixteen years of timing data from the double pulsar confirm the validity of Einstein’s theory of general relativity to a new level and also reveals new relativistic effects that, although expected, have now been observed for the first time. physics.aps.org/articles/…
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πŸ‘€︎ u/MistWeaver80
πŸ“…︎ Dec 13 2021
🚨︎ report
Study: Current global environmental, occupational and food safety standards may be insufficient to protect people from the adverse effects of metals. Environmental exposure to low-levels of the toxic metals arsenic, cadmium and titanium appears to increase the risk of plaque buildup in arteries. newsroom.heart.org/news/e…
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πŸ‘€︎ u/rustoo
πŸ“…︎ Dec 09 2021
🚨︎ report
Can I take ketamine whilst under chemotherapy treatment for lymphoma? Will the drugs react on a pharmacological level and cause adverse effects?
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πŸ‘€︎ u/QuestltseuQ
πŸ“…︎ Dec 09 2021
🚨︎ report
Study: Current global environmental, occupational and food safety standards may be insufficient to protect people from the adverse effects of metals. Environmental exposure to low-levels of the toxic metals arsenic, cadmium and titanium appears to increase the risk of plaque buildup in arteries.

This is the best tl;dr I could make, original reduced by 81%. (I'm a bot)


> Toxic metals in the environment may increase the risk of atherosclerosis, a buildup of plaque in the arteries that can prevent blood and oxygen from reaching major organs.

> Arsenic and cadmium, metals that can be found in food, water and tobacco, plus titanium, which can come from dental and orthopedic implants, cosmetics or auto manufacturing, were associated with a higher likelihood of having clogged arteries in the neck, leg and heart in this study of auto assembly workers in Spain.

> DALLAS, Dec. 9, 2021 - Environmental exposure to low-levels of the toxic metals arsenic, cadmium and titanium appears to increase the risk of plaque buildup in arteries in the neck, heart and legs, according to new research published today in the American Heart Association's journal Arteriosclerosis, Thrombosis and Vascular Biology.

> Prior research on the impact of metal exposure on atherosclerosis has traditionally centered on the carotid arteries, the major arteries in the neck.

> "This study supports that exposure to toxic metals in the environment, even at low-levels of exposure, is toxic for cardiovascular health," said study co-author Maria Tellez-Plaza, M.D., Ph.D., a senior scientist at the National Center for Epidemiology and the Instituto de Salud Carlos III in Madrid, Spain.

> "The levels of metals in our study population were generally lower compared to other published studies. Metals, and in particular arsenic, cadmium, and titanium, likely are relevant risk factors for atherosclerosis, even at the lowest exposure levels and among middle-aged working individuals."


Summary Source | FAQ | Feedback | Top keywords: metal^#1 study^#2 artery^#3 level^#4 health^#5

Post found in /r/science and /r/biology.

NOTICE

... keep reading on reddit ➑

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πŸ‘€︎ u/autotldr
πŸ“…︎ Dec 09 2021
🚨︎ report
Great question: If they didn’t know that the vaccines would lose efficacy over the short term, how can they know that there are no adverse effects over the long term? πŸ€” /r/conspiracy/comments/rx…
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πŸ‘€︎ u/FThumb
πŸ“…︎ Jan 07 2022
🚨︎ report
Could a virus be purposely mutated in a lab such that it will still infect humans, but it no longer has adverse effects? Then, once infected with it, the body would create antibodies that would also protect against the normal virus?

Covid for example, could we mutate it artificially so that once infected there are no adverse effects? Then infect people with this mutated virus to build immunity.

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πŸ“…︎ Jan 11 2022
🚨︎ report
Psylocybin in 10 or 20mg doses had no adverse effects in healthy individuals journals.sagepub.com/doi/…
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πŸ“…︎ Jan 13 2022
🚨︎ report
#PfizerGate FOIA documents reveal that nearly 3% of Pfizer's reported adverse effects lead to DEATH. (FDA wanted this sealed for 55 years, but the Courts said NO!)
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πŸ‘€︎ u/EuphoricTrilby
πŸ“…︎ Dec 02 2021
🚨︎ report
Covid vaccine booster 2 days ago, no adverse effects

Hello people, I got my booster 2 days ago and I'm fine, no adverse effects! I wonder if my sore throat was an adverse effect, but honestly, I didn't have even a sore arm! Moreover, my SOB seems to be almost gone, I will wait until 1 week mark to give you updates :).

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πŸ‘€︎ u/miruntel
πŸ“…︎ Dec 22 2021
🚨︎ report
Reduced agricultural production, water scarcity, rising sea levels and other adverse effects of climate change could cause up to 216 million people to leave their homes and migrate within their own countries by 2050, the World Bank has warned france24.com/en/live-news…
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πŸ‘€︎ u/DoremusJessup
πŸ“…︎ Sep 13 2021
🚨︎ report
TIL that many food colorings widely used within the US are being phased out in Europe due to adverse health effects observed in children. en.wikipedia.org/wiki/All…
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πŸ‘€︎ u/yergi
πŸ“…︎ Dec 14 2010
🚨︎ report
This is delicious. $3 at Target. 2 days no adverse effects (for me) reddit.com/gallery/qi02sk
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πŸ‘€︎ u/krixnos
πŸ“…︎ Oct 29 2021
🚨︎ report
I think the only point of the vaccine is to tell others you have the vaccine. It serves no purpose, other than adverse effects. I say that as someone who recently recovered from a pretty rough bout of Covid.
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πŸ‘€︎ u/quemaspuess
πŸ“…︎ Dec 24 2021
🚨︎ report
Mobile phones and wireless networks: No evidence of health risk found. There is no scientific evidence that low-level electromagnetic field exposure from mobile phones and other transmitting devices causes adverse health effects, according to a report presented by a Norwegian Expert Committee. fhi.no/eway/default.aspx?…
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πŸ‘€︎ u/GraybackPH
πŸ“…︎ Sep 18 2012
🚨︎ report
Arch Angel Walensky (994 MBUH) has seen NO adverse effects on children after 5 million children get the safest vaccine ever. abcnews.go.com/Health/cdc…
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πŸ‘€︎ u/ThundaChikin
πŸ“…︎ Dec 13 2021
🚨︎ report
IRONY: Government creates department (VAERS) to receive and record vaccine adverse effect reports. Government then openly diminishes validity of that same department THEY created while no accredited record-keeping system exists.

Saying that the vaccine manufacturer does this creates even more problems and avenues for discrediting.

What do you think should be done?

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πŸ‘€︎ u/zenwalrus
πŸ“…︎ Sep 27 2021
🚨︎ report
Reducing Blood Pressure using Deep Breathing: No Statistically Significant Effect Observed in First Attempt (Data too noisy) /r/QuantifiedDiabetes/com…
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πŸ‘€︎ u/sskaye
πŸ“…︎ Dec 18 2021
🚨︎ report
Dumb question: Would there be any adverse effects from combining two mods by putting one mod's files into another's folder (no overwriting)?

I use the Mod Limit Adjuster, but I still like to keep my number of mods down as much as I reasonably can. One way I do this is by "merging" mods that have no conflicting files by just combining their folders. For example, if Mod A only has scripts, and Mod B only has .bundle and .store files, I'll put one's files into the other's folder and voila, two mods for the price of one folder. I also do something similar with multiple script mods, as long as no file overwrites.

My theory is, although the game is loading the same number of files, as far as it's concerned it's loading fewer mods, since there are less mod folders. Maybe it's the placebo effect but I feel as though this is easier on the game since it's having to look inside fewer folders and thus, technically, load "fewer" mods.

That's just how I look at it, and it's probably a load of bollocks. But maybe there's some truth to it? That's partly why I made this post. I've read somewhere that what the game considers a "mod" might actually be certain types of files, not the folders that contain them. If that's the case then, well, guess I'm dumb.

I'm, of course, careful with how I do this merging process. I make sure to never overwrite anything, and I generally only merge the smaller, simpler mods together. If a mod has a bunch of .strings files, or is on the more complex side, I'll avoid merging it with anything just to be safe. I also try to avoid merging any mod folder that has an accompanying DLC folder, and I always keep conflicts/priorities in mind.

I keep a text document handy that lists which mods are merged into which folders, and what their files are, so I don't really lose track of anything. Obviously this isn't as easy as each mod having their own folder, but I've grown accustomed to it.

As far as I can remember, I've never actually encountered any issues from merging mods this way. But this hasn't stopped my paranoia of certain mods somehow not functioning as well as they could when merged, than if they were separate. So I've come here in the hopes that someone can set this straight for me once and for all, for peace of mind.

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πŸ‘€︎ u/-GogNoggler-
πŸ“…︎ Dec 14 2021
🚨︎ report
FDA adds β€œwarning” while adverse effects have been covered up, no new trial, or even a complete one.
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πŸ‘€︎ u/Scan8
πŸ“…︎ Dec 02 2021
🚨︎ report
Reducing Blood Pressure using Deep Breathing: No Statistically Significant Effect Observed in First Attempt (Data too noisy)

Full post with nicer formatting and more blood pressure and food effect studies here.

For my studies to determine ways to reduce my blood pressure, the first intervention I'm testing is deep breathing protocols. Here I report my initial results:

Summary

  • Background:
  • Approach:
    • Blood pressure and pulse were measured each morning before and after the following protocols:
      • 8s inhale, 8s exhale, 5 min.
      • Normal activity, 5 min.
      • 8s inhale, 8s exhale, 15 min.
      • Normal activity, 15 min.
    • Each protocol/time combination was measured 5 times.
    • Average and 95% confidence intervals were compared for each metric & protocol.
  • Results & Conclusions:
    • For each time condition, a blood pressure drop was observed on average during deep breathing, while an increase was observed during normal activity. The opposite effect was observed for pulse (increased during deep breathing).
    • Due to the high variance in the measurements, the 95% confidence interval for the difference overlaps zero, so the results are not statistically significant and could easily be due to chance.
  • Next Steps:
    • I will repeat the experiments, but measure blood pressure [5 times for each observation](https://www.quantifieddiabetes.com/2021/12/reduce-blood-pressure-without-medication-phase-0-mea
... keep reading on reddit ➑

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πŸ‘€︎ u/sskaye
πŸ“…︎ Dec 18 2021
🚨︎ report
[#36|+738|234] Rats inhale nicotine vapor 20 hrs./day, 5 days/week yielding twice the nicotine levels of heavy smokers. No 'harmful effect' observed. reddit.com/r/science/comm…
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πŸ‘€︎ u/FrontpageWatch
πŸ“…︎ Aug 01 2014
🚨︎ report
Top minds share lots of stories of adverse vaccine effects, share absolutely no proof of what would be any easy thing to document. reddit.com/r/conspiracy/c…
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πŸ‘€︎ u/illini07
πŸ“…︎ Sep 27 2021
🚨︎ report
Surely like this fight, this will have no adverse effect on the future
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πŸ‘€︎ u/blong217
πŸ“…︎ Aug 04 2021
🚨︎ report
Magnetic Seizure Therapy. One-third of the patients experienced relapse of depression, with no significant differences between those with unipolar and bipolar depression. However two-thirds sustained improvements in depressive symptoms without any adverse cognitive effects. ucsdnews.ucsd.edu/pressre…
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πŸ‘€︎ u/Wagamaga
πŸ“…︎ Oct 24 2021
🚨︎ report
Reducing Blood Pressure using Deep Breathing: No Statistically Significant Effect Observed in First Attempt (Data too noisy) /r/QuantifiedDiabetes/com…
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πŸ‘€︎ u/sskaye
πŸ“…︎ Dec 18 2021
🚨︎ report

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