Autoimmune pancreatitis Puns

If yes what type? What doctors and specialists do you see? Are you on any medications or treatments? How are you doing and feeling at the moment? Do you stick to a special diet? How long did it take for you to get diagnosed? Just saying hello to any fellow AIP sufferers out there.

Not sure which type I have. Currently only seeing a primary physician and looking for a good gastroenterologist. Doctor is sending me to an endocrinologist. Taking low dose Prednisone every other day. Haven't had a flare since I was discharged from the hospital in June of this year. On a low fat, low sugar, low sodium, watching carbs diet. Took me about 3 to 4 months and several ER visits/hospital admissions to get the correct diagnosis. Doctors just thought I was too young to have pancreatitis/pancreas issues and suffering from an eating disorder or seeking attention until an MRI plus 6+ CT scans proved otherwise.

I recently went in for a CT scan of the abdomen due to gastrointestinal issues. I was previously diagnosed with pancreatic insufficiency about 3 weeks ago, and I am on CREON. My physician wanted to focus on my the pancreas. Here are the results:

IMPRESSION:

No pancreatic mass is identified. No dilatation of the pancreatic

duct. Questionable subtle sausage like appearance of the pancreas

raises differential consideration for autoimmune pancreatitis.

Correlate with IgG4 levels. No pseudocyst. No peripancreatic

inflammatory stranding.

My physician had me take blood tests for IgG4 levels to follow up. Levels came back within the normal ranges. IGG came back at 1,234 (still normal) others were in the lower range of normal and ANA was <1:80.

I've read that instances of AIP can correlate with cancer of other organs, which I hope isn't the case. In January, a CT Scan did find two lung nodules (8mm and 5mm) on lower part of my left lung along the hemidiaphragm. I don't smoke. I even had a colonoscopy last week and nothing. Kidneys showed tiny low density lesions too small to characterize. Everything else is clear.

I apologize if this seems like a lot, but I am looking for some insight. This has been the most stressful 2 months of my life and my physician seems pretty nonchalant about my results.

I'd appreciate anything, even support.

Title says it all. I was supposed to be off of steroids months ago and because COVID hit, my GI was scared to lower my dose of steroids because she didn’t want me to have a pancreatic flare-up and end up in the ER and then risk getting COVID.

As a result, I was on a high dose of steroids for an additional four months. Fast forward to today; I now have Cushing’s syndrome and my body is wrecked and I feel horrible about myself. I’m 5’7” and have been 160-170 lbs for 10 years, have had very clear skin, and used to be somewhat attractive. (I’m female.)

Because of the prednisone, I’ve gained 70 lbs that have redistributed exclusively to my stomach, my skin has broken out completely, my face has swollen to twice the size it was before, I have a buffalo hump on my neck, and the deepest, darkest purple stretch marks I’ve ever seen on a person. I used to only have light marks on my inner thighs from puberty, but they’ve stretched along my arms, the entire trunk of my body, and along my back and thighs.

It’s bad enough dealing with the issues autoimmune pancreatitis brings (constant nausea and weekly vomiting) but I’m so horribly depressed by my body too. I genuinely don’t recognize my face in the mirror, it’s so swollen. And when I walk by any reflective surface and catch a glimpse of myself and what I look like now, it makes me want to cry.

Have any of you had to take steroids to handle any autoimmune disorders you’ve had? Have you guys had to deal with the same issue? I’m so upset with the way my body and face look now. My doctor says it isn’t my fault and that there’s nothing I could’ve done to prevent this from happening. Does it get better?

I'm guessing most of us here who were diagnosed with PSC have probably done some research into other conditions that could cause secondary sclerosing cholangitis, in an effort to find a diagnosis that has treatment options.

I recently found some articles about a relatively niche condition called autoimmune pancreatitis, which can cause sclerosing cholangitis. It strikes me as interesting because my own presentation of PSC wasn't typical. Also one of my parents was recently diagnosed with late adult onset autoimmune diabetes, so I'm not sure if there is a connection between autoimmune diabetes and autoimmune pancreatitis.

Some of the reasons I think it may be AIP:

1. Recurrent episodes of cholangitis with no underlying infection.
2. Pain and nausea of cholangitis are always located in the center top of my stomach.
3. Liver enzymes are normal when not experiencing cholangitis.

Some reasons it doesn't match with AIP:

1. Igg4 test was normal, but tested when not experiencing cholangitis
2. Annual mri have found my pancreas to be unremarkable.

My symptoms and frequency of cholangitis improved when I started taking amitrylitptline, not sure why as it isnt a treatment for either condition.

Doctors are considering giving me a ~2 week trial of Prednisone to see if my symptoms respond to the drug and if it might normalize my fluctuating Lipase/GGT levels.

My EUS didn't show any criteria for CP but it did show some things that might hint towards either an Autoimmune issue or perhaps something related to my gallbladder (minimal microlithiasis). Given that the only next step for the gallbladder issue is removal of the organ, steroid trial should probably come first.

My question is for any folk here who have tried Prednisone for a short period for Type 2 AIP, how bad was it? I've heard of some rough symptoms (mental issues/psychosis, bone pain, swollen face, etc) but I wonder if that's more for longer courses of the drug versus short ones. I am going to prepare for the worst, I just hope there's no long-term repercussions.

At this point I'm willing to try anything, hopefully I'm not making a huge mistake.

Hi I was wondering if anyone here has had or knows anyone that has had autoimmune pancreatitis type 2? I suspect I may have this disease although it's tricky to diagnose. I'm also concerned that it could lead to chronic pancreatitis if it's not treated quickly. If anyone has had any experience with AIP type 2 then I would be interested to hear what your experiences were with it. Thanks!

Anyone ever gone through Rituximab infusion to treat their pancreatitis? Doctor is recommending and would like to hear from others.

Just curious if anyone experience a flare up, Dr's not knowing why it happened after x-rays and blood work. Not related to alcohol or stones and you happen to be reasonably fit, and you were careful with your diet and prevented a flate up from happening again? Just curious if this is an option. Thx

I should preface this post with saying I’m new to reddit posts. I’m looking to find other people who have autoimmune pancreatitis—I’ve been told it’s rare and I just want to connect with others who are going through the same thing.

My doctor has diagnosed me with autoimmune pancreatitis. Up until a 3ish years ago I was super healthy with no gastro issues at all. I then had my first major excruciating attack after being terribly sick for 10 days with vomiting, nausea, stomach pain (all the stuff that accompanies a norovirus—which is what I was told I had at the time) that put me in the hospital. It’s been a long journey since then and the pain has never really ever gone away. Some days it’s worse than others. Occasionally I have pain free days (but not recently). Usually the pain just kind of sits at the top of my stomach.. always there even mildly pulsing at a 2-3 pain level. I regularly get super sudden jolts of stabbing pain going all the way to my back that shoots my pain level up to a 10 for a quick instant. This has become distracting at work even (caused me to yelp from pain or gasp in the middle of meetings or in front of colleagues). After the sharp spasms I feel tender and sore for a while and absolutely drained.

I have had so many exams, tests done since the first attack. They gave me my diagnosis earlier this year after an endoscopic ultrasound. My gallbladder works fine. I do not drink except for rare glass of wine. My diet is pretty healthy although I admittedly have a sweet tooth. I do not eat greasy, oily food and mostly avoid citrus. My support system is helpful and cares a lot but this disease has still become super isolating despite having a supportive partner and family. I hurt all the time. Even when I’m happy and laughing and having a good day the pain is usually still there.

My first round of steroid treatment gave me one month of relief but the pain returned and was worse than ever. They started me on steroids again and I’ve been on them for close to 3 months now. I was also on an autoimmune suppressant, but my pain was not going away and my stomach spasms, nausea and headaches got so bad I ended up in the ER (my lipase and amylase is always normal and so folks at the ER don’t seem to believe me when I tell them I have autoimmune pancreatitis). The next week I was admitted to the hospital for several days—- my specialist believes I may have had a bad reaction to the autoimmune suppressant and that it could have caused me

Thread here.

I've seen these threads pop up every now and then, and I usually just stay away from commenting.

It sounds like there are a few legitimate cases of missed diagnoses, but there's plenty of "OMG I had a URI and then 3 days after I went to the doctor I ended up developing pneumonia! What an idiot!"

On the flip side, there are several people complaining about too much testing being done, like the guy who had two cystoscopies for what ended up being a benign condition.

On the whole, people seem to have very little understanding of how the whole process works and why mistakes get made. Maybe we need to listen more? Explain our thinking more? I don't know.

I read that getting a false positive EUS-FNA for adenocarcinoma of the pancreas is a problem in the setting of pancreatitis. What about a rare case of chronic autoimmune pancreatitis along with recent acute attacks? some of the pubmed articles seem to confirm many of the benign resections were a direct result of pancreatitis mimicking cancer. I ask because my mother has had a cancer diagnosis and is to get a whipple in 2 weeks, however she was diagnosed by another specialist last august with autoimmune pancreatitis along with acute attacks for 3 months prior. He beleived the chronic pancreatitis had been ongoing for several years due to her symptoms but local doctors never caught it. the supporting workup was made (serum igg4, history of autoimmune disease, eus ercp etc) and she was placed on high dose prednisone which improved her condition within a month. however a follow up ERCP with FNA found cancer on nov 25. I am worried she might undergo a major operaton for a benign deisease. I am trying to get a 2nd opinion on the slides but its difficult to do in canada unless I wanted to pay a 3rd party.

http://books.google.ca/books?id=CdfsAwAAQBAJ&pg=PA321&lpg=PA321&dq=false+positive+cytology+autoimmune&source=bl&ots=hBnABKyCnl&sig=YeysR0Mrk6FIpwg7O31L0C4SZMM&hl=en&sa=X&ei=k0Z-VNzwNsGlNvnqgbgN&ved=0CGMQ6AEwCQ#v=onepage&q=false%20positive%20cytology%20autoimmune&f=false

http://www.ncbi.nlm.nih.gov/pubmed/16224213

http://www.ncbi.nlm.nih.gov/pubmed/21893326

http://pathologyblawg.com/pathology-news/pathology-vendors/mayo/false-positive-pancreatic-cancer-diagnosis-at-mayo/

http://www.ncbi.nlm.nih.gov/pubmed/21737075

My husband was in extreme pain yesterday and vomiting. I could barely get him in the car to take him to the hospital. He threw up several times on the way while scream-moaning.

We got there and I rush in to get someone to help him because he can't make it out of the car by himself. They wheel him in, take his info and then say, "I hope you brought your patience, we're extremely busy today." And I said, this isn't a minor situation, he thought he was going to die on the way here." He actually started telling me where all his important docs were and how to get rid of his stuff 'just in case' on the way there. It was bad.

So she says, "I've noted your situation and you'll be called when they're ready." I'm in disbelief. He's doubled over in a wheelchair, moaning and vomiting and he looks absolutely terrible.

In strolls a middle aged woman looking completely fine. Since we were sitting about 12 feet away from reception, we could hear the conversation.

Her: "I was just at urgent care and they sent me here because my O2 stats were a little low and I've been coughing a little."

Desk: "Have you been vaccinated?"

Her: "No. They said I have covid at urgent care. They told me to come here."

Desk: "Ok, wait here."

Meanwhile, she's just chatting with her husband, in no distress whatsoever. She strolls over to where me and my husband were and stands 3 feet away. I'm thinking, "Are you fucking kidding me?" I want to scream at this woman, but I don't need security being called and throwing us out.

15 seconds later, they call her name and bring her back and I can hear them treating her. (This was all in a pretty small space. The reception was close to our left and the treatment rooms were close to our right and they kept the door open). They're asking how she's feeling, take her blood pressure, the usual. She's chatting and making jokes. I still haven't heard her cough yet.

Meanwhile, my husband looks like death, is panting and moaning. They call another person back, who strolls over while browsing her phone looking like not a care in the world.

Nurse: "You're not vaccinated, is that right?"

Person: "No."

Nurse: "Ok, you can come back now."

It's been 15 minutes that we've been waiting now, which when you're in that much pain and distresss, feels like 2 hours, and no one they've called back looks like they're in any kind of discomfort whatsoever. I overhear them saying at the desk, "people are just going to have to wait a few hours". I'm

Really sorry this is so ridiculously long but I want you to have complete info.

Species: Dog

Age: 11 yo

Sex: Female spayed

Breed: Beagle

Weight: 27 lb

History:

-a few UTIs in early years, resolved when dx with recessed vulva and we wipe her with Malaket after walks.

She had anaplasmosis and Lyme (we lived in NJ, now SC), both treated and resolved with abx.

DX in 2018 with kidney disease possibly due to Lyme, takes Calcitriol 2x/week, eats SD KD food, takes this 2x/day: Pet Wellbeing Kidney Support Value Size - Natural Support for Kidney Problems with Cats & Dogs - 4oz (118ml) https://www.amazon.com/dp/B01C9BBEV6/ref=cm_sw_r_apan_glt_fabc_CD1T59GCWVC88SB299GA The herbal thing was rec by a prior vet that had good experience with it. Her kidney labs have consistently been normal with no changes in treatment needed.

DX in 2021 with MVP and then enlarged heart, then CHF, has been stable since 9/21 with no crackles, breathing is <30/min, she's active, able to jump, run upstairs. She takes 2.5mg Vetmedin 3x/day; 5mg Enalapril, 25mg Spironolactone, and 32.5mg Furosemide 2x/day.

It is a miracle that both conditions are stable given the difficult balance in treatments for heart and kidney disease.

She's had stomach issues before due to her eating garbage in neighborhood ie french fries, candy, bones. Also, because of CHF she hasn't had vaccinations in a year.

Clinical signs:

She stopped eating her KD food last week and we've been giving chicken. She would take her meds with that or peanut butter, but now she's not taking meds or eating the chicken or her food. Also has bad gas and a little diarrhea. She had some tuna today but not taking meds. She has been less active for a few days, almost seems depressed. Less interested in walking but had a peppy walk last night and ran upstairs.

Diagnostics:

Went to vet yesterday and xray shows enlarged liver and spleen. Last xray was in 5/21 and organs were normal.

Labs:

Just putting down the abnormal findings. These are too low...

WBC 3.75

NEU 2.74

LYM 0.79

EOS 0.01

PLT 98

MPV 7.0

Sodium 139

Potassium 3.6

Chloride 90

These are too high...

ALT (GPT) 378

ALP 684

GGT 22

Last labs were in 10/21 and all was normal.

Vet thinks it's either cancer, pancreatitis, and/or infection. He RX Cerenia, Endosorb, Metronidazole, and Amoxicillin. She had a shot of Cerenia yesterday. He said hopefully she will eat and symptoms will resolve in a day or two with the meds. He said if not, it may be time

Hi all - after a long awaited but discouraging appointment with a rheumatologist, I'm turning to Reddit for some advice from you all.

I've been dealing with persistent and worsening GI issues since roughly mid-2018, following having pancreatitis and needing my gallbladder removed in February of 2018 (cause never determined), with the symptoms being the worst since the beginning of 2020 (great timing, I know). After a recommendation from my eye doctor to address the possibility of an autoimmune disorder, prompted by severe dry eye and eye inflammation, I visited my PCP and requested she run an ANA test. She said no and instead referred me out to GI, which, given 2020, took a long time to actually get into. In October of 2020 the GI doctor did a colonoscopy which came back normal, and in early 2021, did a capsule endoscopy, which also came back normal. She also tried me on Xifaxan, hyoscyamine, and dicyclomine, none of which helped my symptoms. She also ran a occult blood stool immunochemical test which came back positive and abnormal. However, calprotectin fecal, pancreatic elastase, tissue transglutaminase Ab, IgA, and immunoglobulin tests all came back normal.

In September of 2021, when GI symptoms worsened and pancreatitis-symptoms returned, I went back to the doctor and saw a new PCP. He, luckily, listened and ran aspartate aminotransferase, alanine aminotransferase, CPR, ESR, RF, lipase level, and an ANA (finally!). Of course, it was the ANA that came back positive/abnormal and high, 1:640, and homogenous. This triggered a referral to the Rheumatologist, an appointment I hoped would bring me answers for once. However, my appointment was today, and the doctor lead with telling me how concerning my ANA results were, saying she doesn't specialize in GI and can't address those issues, and quickly moved on to focusing solely on the dry eye and psoriasis (which appeared in 2020 as well). She's referring me out to Dermatology and doing bloodwork to test for Sjogren's Disease, but didn't address any of my GI concerns. After doing some Reddit reading and research, I'm seeing that Sjogren's can have GI symptoms associated with it, but this was not something she addressed at all (only mentioned eyes/mouth/liver/kidneys). She ended by saying if the bloodwork for Sjogren's comes back normal then I "must just have a high ANA," and "if I don't meet the criteria yet then I don't need to be seen again," despite starting the conversation by telling me how concerning

Hi

I'm in my 20's and got pancreatitis, probably due to alcohol, it's still unsure since doctors can't figure out if it's acute or autoimmune.

Question is. How do you handle situations where people expect you to drink, and does restaurants & bars in Europe have non-alcoholic beers?

I want to be able to drink 1-2 non-alcohol beers every now and then, I'm just unsure if people in cultures with heavy drinking understand, that if I drink alcohol, my pancreas & liver both will make sure I won't be able to eat & move due to immense pain.

Hi there,

I've been having monthly acute pancreatitis for over 2 years now. I'm male, 28, no smoking, no alcohol. These attacks happen literally every month (with two or three exceptions) no matter what I eat or drink. I tried eliminating fatty foods, and it didn't help.

Last time I had it (20 days ago) I don't think it was due to food, but more due to stress - so my first question is: can pancreatitis occur due to stress?

I must mention that I've done every investigation possible (from ultrasound during the attack to MRCP to MRI to endoscopy to gastroscopy - before, during and after the attacks). Tested negative for bacteria (haven't done a SIBO test yet, though), negative for autoimmune pancreatitis, and all my tests came back good.

My amylase and lipase levels are always high during the attack (around 1000), however they go back to normal after a couple days. My abdominal pain is mild and goes away after 1-2 hours, and then I only have some sort of discomfort that lasts for a maximum of one day. All bearable. I must mention that when it happens, it always happens a couple hours after my lunch - never after breakfast, dinner or at night.

After all my tests, the diagnosis was "idiopathic pancreatitis" - and so my question is: can idiopathic pancreatitis be acute or is it automatically chronic? My doctors assured me it's not chronic since my pancreas isn't scarred and looks all good.

Is there anything left for me to do tests-wise? The only thing that I didn't do is a CT. And I didn't do the genetic tests for pancreatitis either.

Many thanks for your help!

Andrew

For context, I was diagnosed with type 1 diabetes at the age of 13. It is an autoimmune disease where the immune system kills pancreatic cells, and management of the condition requires a great deal of carb counting and paying attention to nutrition info. I think it may have contributed to my ED, both due to the misunderstanding around it (some people would think I have type 2 and would suggest I go on a diet, which I’ve never actually needed) and the heavy emphasis on measuring and thinking about food. I’m having to manually perform an automatic bodily function by myself, after all.

So now I’m in that stage where I’ve gotten a better mindset about food and actually want to eat it. I still have some weight to gain before I reach my set goal, but it’s a slow process— it gets difficult to eat enough when I have to really worry about how it affects my blood sugar. I technically don’t have to restrict carbs, but it does get quite hard to eat more of them since insulin dosing isn’t near as perfect as it is when the body does it. If I eat a lot of carbs, I risk taking too little insulin and suffering high blood sugars, or I risk taking too much and passing out or something really bad. It’s just a tricky thing to have to think about.

I do have a nutritionist who knows about t1d and who tries to create reasonable meal plans for me. Some of the ideas are very good, but others— especially the breakfasts— are more carbs than I think I could handle in one meal. I also have researched sample meal plans online out of curiosity and I was disappointed to notice that they all consist of heavy amounts of carbs. 100g of pasta, bread, rice, etc. when I’m still only able to have about a half cup of rice. Most recovery pages also stress that carb consumption is extremely important, and that you need carbohydrates to heal. How can I recover without something so important? I feel ashamed for still having to restrict.

Then there’s the topic of “food freedom”. If I’m truly recovered, I should allow myself to eat a donut spontaneously or to add honey to bread or to drink a milkshake or eat cookies at 11:00 PM. I see fellow people in recovery enjoying this new freedom, and of course I’m happy to see people gaining their happiness and energy back. But I can’t do the same myself, and it makes me feel like relapsing and going back to my ED is the better option for managing my health. I know I can’t do that. But recovery and t1d just don’t go together and I’m struggling because of it.

Phase 1 (safety) trial to start in Canada.

Viacyte has been working on creating implantable pouches full of pancreatic cells that would produce insulin.

This new project is not quite the same as their PEC-Direct (VC-01) which would require immune suppressants; or PEC-Encap (VC-02) which would keep the immune system out of the pouches.

This is a newer project, called PEC-QT or "VCTX210," and it will allegedly contain engineered pancreatic cells that will not be susceptible to autoimmune destruction.

Press Release:

https://crisprtx.gcs-web.com/news-releases/news-release-details/crispr-therapeutics-and-viacyte-inc-start-clinical-trial-first

From their website:

For PEC-QT, ViaCyte’s proprietary CyT49 pluripotent human stem cell line will be specifically engineered to avoid destruction by the patient’s immune system, potentially eliminating the need for immunosuppressants. The cell line will be differentiated into pancreatic endoderm cells, which will likely be housed in the same type of device used for PEC-Direct, which allows direct interaction between blood vessels and the implanted cells, but because the cells are being designed to be immune-evasive, we would not expect them to be rejected by the immune system. ViaCyte and CRISPR Therapeutics formed a partnership in 2018 to discover, develop, and commercialize gene-edited allogeneic stem cell-derived therapies which could be a next-generation functional cure for all insulin-requiring type 1 and type 2 diabetes.

https://viacyte.com/stem-cell-engineering/

https://www.cirm.ca.gov/our-progress/awards/preclinical-development-immune-evasive-islet-cell-replacement-therapy-type-1

[Don't ask me if it is worth anything or phony-baloney, or "just 5 to 10 years away." Viacyte is a private, for-profit company. Crispr Therapeutics is a public, for-profit company. ]

I have been on cymbalta for almost 20 years I’ve tried go off but never seemed worth the withdrawal. For the past 3 years I’ve been plagued with health issues and I’m beginning to realize from research it corresponds directly with an increase of my cymbalta from 60 to 120) And by health issues I mean debilitating and i used to climb mountains, have an awesome job as a curator. Im now unemployed and i cant barely be motivated to watch tv. I’ve gone from a 90 pounds to 180 (which I can’t lose I’m adderall I try to work out when I’m physically able and I eat so healthy. I used to live off double cheeseburgers and wine) I gave up alcohol , my hair has fallen out, I get a psoriasis like rash, joint pain, stomach issues. I’ve developed hypothryroidism, Anemia, gallbladder removal. My blood work is always off hormones crazy, my white blood cell high, platelets low, AST and ALT show something is off with my liver. I’ve been to so many doctors they’ve tested me for literally everything especially after I had severe ecclampsia with my daughter and they are all baffled. I kind of am presenting as having auto immune disease but I assure you I do not have it and even with like the ecclampsia and severe pancreatitis its always considered “atypical” I was just in the hospital for pancreatitis and first diagnosed with auto immune pancreatitis. It’s insanely rare but on a cat scan it’s undeniable the pancreas is damaged in a very particular way. Once again no bio markers for autoimmune disease so it can’t be. Drs are stumped the send me home and promise me they’ll figure it out. I started to notice my pancreas pain was coming 30 minutes on the dot after I took cymbalta. Has anyone else had anything similar? Did your symptoms go away?

Hey folks, just realized that I never updated y'all, so here it is:

Recap: I've had 17 attacks/flares of acute pancreatitis in the past five months, leading to three hospitalizations. My symptoms seemed to be unrelated to any food triggers, and between attacks, I felt completely normal. My increasingly befuddled doctors ruled out trauma, alcohol, gallstones, high triglycerides, Celiac disease, diabetes, autoimmune, genetics, cancer, and foreign scorpion attacks as the cause. With little other recourse, they recommended that I have a laparoscopic cholecystectomy (keyhole surgery to remove the gallbladder).

The surgery went without a hitch and I'm six weeks into a very smooth recovery. I haven't had any attacks in that time, which is easily the longest I've gone since all this started, so I'm cautiously optimistic that my case has been solved. My pathology report indicated cholesterolosis (gallbladder polyps).

A brief consultation with Dr. Google showed that this area is understudied (of course), but there are a couple publicly accessible papers that suggest causation between cholesterolosis and recurrent acute pancreatitis.

As to what caused the polyps themselves, according to my surgeon: "It's just one of those things that can just happen." 😑

Anyway, I thought it might help fellow idiopathic pancreatitis sufferers to share this, rare though it apparently is. Unfortunately, it took cutting out an organ and gazing upon it with the naked eye to detect the polyps; at least in my case, they never showed up on any ultrasound, CT scans, MRCP, or EUS.

Let me start by introducing myself.

I’m a 25 year old male who has been healthy all his life but I had my first attack 2 years ago.

I only drank socially and I’ve never smoked and all my life I ate healthy with lot of vegetables fruits and rarely ate fatty or processed foods.

Since then I’ve had 6 more attacks each own being weaker than the last.

Also the highest my amylase ever gotten was 360 which I think it’s kinda low.

Important to mention that I’ve failed to see any relation on what I eat and my attacks. It seems completely random.

My pancreatitis is idiopathic and no one knows why it keeps happening. I’ve had a recent CT scan after my last attack and my pancreas seems to have no permanent damage besides being inflamed.

Now that you know a bit about me let me ask some questions.

1-From what I’ve read from this subs people experience a lot worst symptoms than me. After I have my attack I usually fast one day. And start eating on the second day non fatty food and after 1 week I start eating normally. Also the pain from the attack is only one instance. After it goes down it doesn’t appear again. My question is this is common?

2- my second question is in relation to protein powder. Can I keep using it normally everyday? I haven seen it mentioned anywhere.

3- I still haven’t checked for autoimmune type 2 and for genetic pancreatitis. Is there any advantage in finding if this is the cause?

4- I’m trying to gain weight so I keep trying to eat 3500kcals a day. Do you think this could be a problem for my pancreas since it’s to much? I really don’t want to be skinny all my life and I’m trying extremely hard to gain weight. This last 5 months I’ve gained 10kg but every attack is a huge setback since I always lose weight.

5- kinda repeating myself but is it common for the pain to only appear one time per attack? I’ve read some posts and it seems a lot of people keep having pain for a long time.

6- is a huge loss of appetite after an attack normal? 2 weeks have passed since my last attack and I’m having a really hard time eating the 3500kcal per day.

7- I keep feeling fatigued since my first attack. This is the worst symptom that even after eating healthy and sleeping a lot I keep feeling tired. Sometimes it gets a little better but it’s something that I’ve had for the last two years. Does anyone else experience this?

Thank you for reading : )

I'm asking for advice. I'm a 20F who was hospitalized about a year ago for severe pancreatitis with no known cause. Since then, I've had consistent pancreas pain and my stomach is almost always hard and distended, although occasionally it will go away for no clear reason.

My gallbladder is fine; we did ultrasounds and endoscopes and everything to prove that there were no stones or issues. I've been to three GIs: one wanted to diagnose with autoimmune pancreatitis, and the other two basically said I had to have another severe case because they would diagnose me with anything. The most recent one said that she thinks I just have really small stones in my gallbladder that no one can see, but this seems so unlikely to me given how much pain I'm in. None of them will do any further testing until I get severe pancreatitis again, even though I'm in near constant pain. I don't want to have to wait until I'm forced onto pancreatic rest again for answers.

I've had what I now realize is pancreas related issues for a long time, but they were misdiagnosed as generic stomach issues/pain. My GIs agreed that those past cases throughout the years were also probably pancreatitis, but they still won't consider them "proof enough" that something is wrong. I've never drank or smoked, and a lot of my family medical history is missing.

Every time they preform blood tests in the past few months (for suspected less severe cases) nothing comes back indicating pancreatitis but I'm malnourished every single time (I'm chubby so they act like this must be a mistake but I'm just as confused as they are). I'm getting to a point where I can't eat without any pain. I've been diagnosed with IBS in the past, as well as PCOS and POTS. I'm very frustrated and near a breaking point with my physical health. I'm always in pain and I can't even eat anymore. I don't know what to do, and ever since I was diagnosed with anxiety most doctors won't take me seriously, despite my anxiety not being health related. They all just tell me I'm too young and that it's nothing but I'm getting very depressed over the whole situation. Any advice would be welcomed.

Fehrplay’s Long term Stock Due Diligence:

All Info here was pulled from Filings, PRs, or from their website.

Website: https://creativemedicaltechnology.com

CELZ: Similar companies BCTX, LGVN, ATHX

Fehrplay’s First thoughts: CELZ is an intro Biotech company that patents procedures for many long-term diseases that currently DO NOT have cures.  For me the biggest prospect of their technology is that since they use the same procedure for every single therapy if they get approval for one, they will most likely get approval for all.  This is not a drug this is a procedure of getting the Stem Cells to react and attack what they want.  They pull the stem cells out and reprogram them to do what they want. ImmCelz® is an immunotherapy product in which stem cells are used to "educate" immune cells to endow them with regenerative activity. The Company believes that "educated" immune cells may be superior to stem cells because of their: a) ability to replicate and form "memory" cells; b) substantially smaller size, which allows for superior biodistribution than stem cells; and c) adeptness at surviving in conditions such as hypoxia or acidosis, which would inactivate stem cells.*

Patents: Creative Medical Technology Holdings has developed/acquired a robust intellectual property (IP) portfolio related to the utilization of stem cells to improve patient lives in the areas of Urology, Neurology and Orthopedics.

This IP portfolio positions us at the forefront of the regenerative medicine industry (set to grow to $39Bn by 2023). We plan to commercialize these products on our own and in collaboration with strategic partners.

Areas

Patent

Description

Urology

US20180015127A1

Methods for Treatment of Premature Ovarian Failure and Ovarian Aging Using Regenerative Cells

Urology

US8372797B2

Treatment of Erectile Dysfunction by Stem Cell Therapy

Urology

US20180325959A1

Methods of Treating Erectile Dysfunction Using Regenerative Cells and Therapeutic Energy Treatments

Neuro/Oncology

US20190022147A1

Treatment of Glioma by Amniotic Fluid Stem Cells and Exosome

Hey, all. I was wondering if anyone else has experienced this? For background, I’m going to share my story.

I started getting sick when I moved from IL, USA to FL, USA and had really bad nerve pain. Now, prior to moving, I had severely injured my back when I played softball. I thought the pain was from that but it wasn’t subsiding. I went to the ER as I was in tears and they checked my bloods. I was then diagnosed with hypothyroidism and discharged with a referral to an Endocrinologist.

Almost 1 year later, I became very sick. I was constantly throwing up and was in so much pain. I was miserable. I found out I had pancreatitis. When it was cleared up, the pain stopped but the nausea, vomiting, etc. didn’t let up. My PCP gave me a referral to a gastroenterologist and I was then diagnosed with Celiac Disease via endoscopy and bloods.

Another 1 year later I started getting very weak when I was working. I was a lifeguard and would also work out all the time so I was very aware of my body. It was something I’ve never felt before. I felt like collapsing of weakness and fatigue every day and noticed that my heart rate was reaching very high levels and I was feeling sick. I quit my job at that point and started to seek medical care (as heart disease runs in my family). I was diagnosed after 4 months with dysautonomia and hEDS (which is extremely mild and never knew I had it). I just kept getting worse and worse over the course of that year. I am now 1 year on treatments including 1L IV saline every day.

I feel like everything just snowballed. I know that once you get an autoimmune disorder or chronic illness, you just keep developing more. Does anyone else have a similar experience? Has anyone else’s POTS rapidly developed/progressed/got worse in a short period of time? I’m kind of scared about how much worse it can get. I’m a student and am struggling massively with classes and keeping up with schoolwork but I am very dedicated to getting my degree. By the looks of it, I’m going to be a part time student only doing 2 classes at a time until I can get my bachelors.

Do your worst!

This piece went live for a few hours at The Automatic Earth blog where it causes a sensation and then quickly went off-line.

Copy and paste this to your own local drive as it’s being taken down net-wide as fast as it appears

Fortunately a few archives were made, and here’s the text of the letter:

Hello,

My name is Spartacus, and I’ve had enough.

We have been forced to watch America and the Free World spin into inexorable decline due to a biowarfare attack. We, along with countless others, have been victimized and gaslit by propaganda and psychological warfare operations being conducted by an unelected, unaccountable Elite against the American people and our allies.

Our mental and physical health have suffered immensely over the course of the past year and a half. We have felt the sting of isolation, lockdown, masking, quarantines, and other completely nonsensical acts of healthcare theater that have done absolutely nothing to protect the health or wellbeing of the public from the ongoing COVID-19 pandemic.

Now, we are watching the medical establishment inject literal poison into millions of our fellow Americans without so much as a fight.

We have been told that we will be fired and denied our livelihoods if we refuse to vaccinate. This was the last straw.

We have spent thousands of hours analyzing leaked footage from Wuhan, scientific papers from primary sources, as well as the paper trails left by the medical establishment.

What we have discovered would shock anyone to their core.

First, we will summarize our findings, and then, we will explain them in detail. References will be placed at the end.

Summary:

COVID-19 is a blood and blood vessel disease. SARS-CoV-2 infects the lining of human blood vessels, causing them to leak into the lungs.

Current treatment protocols (e.g. invasive ventilation) are actively harmful to patients, accelerating oxidative stress and causing severe VILI (ventilator-induced lung injuries). The continued use of ventilators in the absence of any proven medical benefit constitutes mass murder.

Existing countermeasures are inadequate to slow the spread of what is an aerosolized and potentially wastewater-borne virus, and constitute a form of medical theater.

Various non-vaccine interventions have been suppressed by both the media and the medical establishment in favor of vaccines and expensive patented drugs.

The authorities have denied the usefulness of natur

Hello everyone! Long time following and admiring this sub, first time posting on my new account.

As of today, I weigh 240 lbs. I’m 5’4” and I’m 28 years old.

I wasn’t always obese. I used to run marathons, played varsity tennis and badminton in high school, and was always out hiking and biking during the weekend.

Around 18 years old, I was diagnosed with Crohn’s Disease. Then later, I was diagnosed with psoriasis, psoriatic arthritis, lymphocytic colitis, fibromyalgia, and other conditions down the line including two (indeterminate) liver tumors. I developed the majority of my chronic autoimmune conditions during the healthiest period of my life. My symptoms were out of control and my specialists put me on long term high dose steroids to help with inflammation. I gained 60 lbs in one year because of the steroids. Eventually, I was not able to work for a while because of how sick I became. Because of a Crohn’s flareup, I lost a lot of fluids and had acute renal failure and pancreatitis. I was hospitalized for two weeks, and recovery went on for a while longer. During this period, and up until now, I’ve lived a mostly sedentary lifestyle (especially during the pandemic). I stay well nourished and rarely eat out, but the majority of my weight gain besides the medication comes from being sedentary, having a lot of stress from physical and environmental factors, and lack of sleep because of chronic pain. Every time I start exercising, even if it’s just walking every day, something happens with my disabilities where I have to stop for a week or more, and I lose consistency. I’ve learned over time to know my limits and listen to my body, but I feel like it’s a vicious cycle and I feel like I’m at a loss at this point.

I’m posting this here because I’m seeking help on how to be consistent with exercise and a healthy sleep schedule and not give up. My weight is not helping my psoriatic arthritis because the weight puts more pressure on my joints.

Thank you for reading!

*My health conditions are chronic, and I’m currently taking a treatment that works for me. No need for unsolicited medical advice, thanks in advance! 🙂

Has anyone on here had experience with an idiopathic CP diagnosis? My partner was recently given that diagnosis after a year and a half of acute pancreatic episodes and no cessation of pain after his initial episode. They’re a non-smoker, haven’t had a single drink since the first hospitalization and is strictly following a low fat diet. The pain is so bad most days. Looking for advice, anecdotal things to try, or just general commiseration. Or if anyone has found a root cause for CP beyond alcohol, gallstones, and autoimmune (these have all been ruled out). We’ve had so many bad experiences with medical intervention, and are feeling a bit lost.

I'm surprised it hasn't decade.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.