Peonidin 3 Glucoside Puns

Just wondering if anyone has had any experiences with this substance as a nutrient partitioning aid or for any other use. There aren’t many human studies on it so I want to see if anyone has some personal accounts of how it worked and how it affected them

Does ND have anything similar to C3G? I assume my best bet would be Berberine HCL + silymarin?

I know the tart cherry supplement contains some C3G, but I was wondering if ND was thinking about sourcing and producing a stand-alone anthocyanin supplement like this.

There’s only one other company on the market that does it right now, and I honestly think it was one of the few supplements that I noticed a significant change in body composition when I took it.

The ordinary website states any strong acids destroy EUK 134 so direct vitamin C is a no go. I know I can't use Ferulic acid with EUK 134 so I use those on sperate times. My question is, since ascorbyl glucoside is a vitamine C derivative, if I can use it with EUK 134 to boost antioxidant properties or if the ascorbyl glucoside will make the EUK134 less effective. I can't find this information anywhere! Thanks in advance ✨

I'm a little confuced since EUK 134 0.1% conflicts with direct Vit. C but not so much with Vit C derivatives. Resveratrol 3% + Ferulic Acid 3% doesn't seem to conflict with any type of Vit C. Information on the products says water can impair the stability of any antioxidant, I'm guessing that's why both the antioxidant serums are anhydrous. The ascorbyl glucoside solution 12% on the other hand is water-based, that's why I'm not sure if it's alright to mix the products for more antioxidant properties or just layer them. If I layer them, I should use waterbased Vit C before the anhydrous antioxidant serum right?

I'm sorry if my post is a little confusing. I'm confused as well lol.

Hi, I’ve been using vitamin C serums for a few years now. My knowledge improved over time, but I just didn’t see any effects. Lately I bought a sephora collection serum, the c+e one. Ascorbyl glucoside is the ingredient in it, but it’s listed long after the perfume which makes me think it’s below 1%.

Somehow I saw some improvement! But I’m worried it’s some short-term effect from the extracts. And I’m afraid that it won’t boost collagen production like an ascorbic acid serum would.

The question here is if it’s worth to stick to that SC serum, buy another adscorbic acid, or maybe try higher % of ascorbyl glucoside serum? I’m thinking the ordinary 12%.

I just thought that maybe this is the right derivative for me… but again I’m worried it’s not gonna be effective long-term.

Maybe someone here could confirm that AG could be more effective than AA for some? Or knows a study that compares them?

Hey everyone, I'm wondering if someone can explain to me the science behind a drug that can treat multiple viruses (including potentially COVID19)? I heard something like... "all viruses have X in common and this drug attacks X".

The two key researchers are. Majambu Mbikay and Michel Chrétien. Their article on this drug is here: https://aac.asm.org/content/60/9/5182.short.

When I say "all", I think he meant ebola, zika and now potentially COVID-19.

They have yet to publish an article on the treatment to COVID-19, but in the interview I heard, they were beginning mice trials to test its efficacy for COVID-19.

I'm a natural bodybuilder looking to get the most out of my workouts. I've been digging deep into the science of MPS, insulin, and all that stuff. I came across the Indigo-3G, with what looks like some good reviews, but that price tag seems a little excessive.

So my question is:

1. what is the secret Microemulisfying Nutrient Delivery System
2. does it even work
3. how can I get the most out of c3g if I buy it from either black bean extract retailer or in bulk from a site like alibaba. Alibaba says that their concentration is 5-50% HPLC, what does that mean and how does that translate to the 600mg in Indigo.

I'd appreciate any info I've searched a lot but I can't find a good apples to apples comparison. I know ISatori has a supplement out now that has C3G in it with its own "nutrient Partitioning" so someone out there must have cracked the code on Indigo-3G

My skin really likes ascorbyl glucoside but so far the only products I have tried are The Ordinary Asorbyl Glucoside, which was kinda sticky and left a bit of a film.

And Melano CC cream which I'm using atm but I suspect it's kinda low %

Does anyone know any other products?

I’m wondering if it was effective for you?

details: An test tube equipped with a magnetic stirrer bar will be charged with the substrate (1.0 equiv. pNPG (paranitrophenyl β-D-glucoside)), tetrabutylammonium hydrogen sulfate (0.30 equiv.) and phosphoenolpyruvate monopotassium salt (4.5 equiv.). To the reaction mixture, add N,N-dimethylformamide (0.20 M) at r.t., and warm the mixture to 100 °C. After stirring for 6 h, the reaction mixture will be cooled to r.t.. The problem is I don’t have preparative chromatography with me can I purify the product (pNPG-phosphate) in any other way and later analyse it. My goal is to use this product in a biological reaction assay thus I need to redissolve it in a buffer.

It's been known for a while that the anthocyanin's had some very impressive health promoting effects in vitro.

For example in the case of cyanidin-3-glucoside (which is naturally occurring in black rice, black beans, elderberries in reasonable quantities).

Increasing insulin sensitivity by up-regulating PPAR-Gamma, improving lipid and triglyceride metabolism by increasing myocytes (muscle cells) glucose and lipid uptake, caused by potent AMPK activation.

Without hindering muscle protein synthesis that is associated with AMPK activation.

As well as retinal pigment epithelium preserving qualities.

A known bioavailability issue may have been one of the factors their in vitro results never translated well in vivo.

This bioavailability is due retinoid metabolism, the P450 enzyme which is involved in the excretion caused by glucuronidation, P450 inhibitors such as brassica vegetables increase and apiaceous vegetables (celery, parsley, parsnip), grapefruit is also a potential possibility of increasing bioavailability.

Rich dietary sources of quercetin could provide an interesting synergy.

Has anyone experimented with this?

So I've been researching just general nutrient disposal agents that can influence muscle more than fat. I'm starting to branch out past glucose, and starting to look into fatty acid disposal into muscle as well (since if it gets into muscle, it will most likely be acutely oxidized since it can't be stored too easily).

As much as I research and branch out, Cyanidin-3-Glucoside (the newest compound from Biotest) still remains the best compound in this general field. Why this frustrates me is:

• Biotest has a current monopoly on the liposomal delivery system (needed) for high dose Cyanidin-3-Glucoside (high dose needed)

• Its mother fucking $480 for 6 weeks

I'm looking into a way to mimic the delivery system (with help of redditor pwoolf) so potentially we can use non-liposomal delivery agents of Cyanidin-3-Glucoside for cheaper. However, I don't know if those exist.

So yeah. Has anybody come across other companies selling Cyanidin-3-Glucoside in relatively high amounts? (High amounts means that 150mg/kg bodyweight in some studies, and 2g from Biotest, the former according to Examine)

I’ve used up 2 bottles over the last 4-ish months, and here are my thoughts:

-Post Inflammatory HP: This was the reason I bought it. In all honesty, it really didn’t do much. I get hormonal acne around my chin and across my forehead that (even if left alone) always leaves PIHP spots that stick around for quite a while. I do think that it made a very slight difference in the time it took for these spots to go away, but not enough to really make me want to buy it again.

-Congestion: While it’s not the primary purpose behind the product, I have seen many reviews saying that it makes a big difference. I saw no improvement with congestion with this product. That is not to say that it broke me out, because it did not as far as I can tell.

-Overall Feeling on Skin: I’m a fan of the way it felt on my skin. It was very lightweight and made my skin feel slightly plump and nourished. It did not cause my moisturizer to pill or react adversely.

-Other: My only true issue with the product was the smell. I’m not typically sensitive to the natural smells of products and I don’t use anything fragranced as my skin doesn’t tolerate it well. That said, this is the absolute worst smelling product I have ever used. It has a very strong dead fish smell from the second you open the bottle. It does linger for quite some time on your hands after applying it. This was a big part of why I decided to only use it at night. I’ve never seen anyone else mention that about the product, but it happened with both bottles, one from their site, one from Ulta.

-My Info: I have normal-dry skin that can be mildly sensitive. My main skin issues are congestion and PIHP.

-My Routine:

Morning: CeraVe Hydrating Cleanser, TO Hyaluronic Acid + B5, TO Niacinimide + Zinc, CeraVe Moisturizing Lotion, Pipette Baby Mineral Sunscreen SPF 50,

Night: repeat of steps 1 and 2, TO AG 12%, Differin Gel spot treat on active breakouts or serious dark spots, Rosehip Seed Oil, same moisturizer as morning

I've seen the shit on T-nation. Still a bit overpriced IMHO, but I think the price has dropped a bit. I'm curious though to find out the results anyone has had on it. I cannot find any logs that are independent or completed in the last 12-18 months that are not affiliated with T-Nation.

Anyone try it? Anyone know anyone?

Also I know that I can get probably the same amount with blueberries/blackberries, but I'm curious to try something with less sugar than fruit berries.

I'm not educated enough to understand the science mumbo jumbo TNation is spewing about their new product, but boy do they make it sound good. Christian Thibaudeau, Chris Shugart and the rest of the TNation crew are jizzing their pants over it, but the training logs seem to be just a little underwhelming for the almost-$500 pricetag. As one bb.com user put it, "For $480 Christian Thibadeau better personally deliver this to my doorstep and suck me off."

What do you guys think?

Hi guys:-) Can Niod Modulating Glucosides be used right after Retinl-A application? Is anyone doing that? Thnx!

I'm not to worried about the price, but this supplement seems pretty remarkable. But, if cyanidin 3-glucoside (Biotest Indigo 3G) is an antioxidant, wouldn't you want to stay away from it before, during and after workouts?

I’ve been using this product for around two months now and I noticed that I break out more on it. Does it have a purging phase? If not, should I stop using it?

I dont want to give up on vitamin c just yet

Does anyone know anything about improving C3G absorption to make it more cost-effective? What is the lowest effective dose? How long would it take to start getting results?

Thanks.

The examine.com page says it seems to have poor bioavailability. Anyone have any thoughts or experience with this?

First of all I know about conflicting products but that information doesn't answer my question. The ordinary website states any strong acids destroy EUK 134 so direct vitamin C is a no go. I know I can't use Ferulic acid with EUK 134 so I use those on a sperate time. My question is, since ascorbyl glucoside is a vitamine C derivative, if I can use it with EUK 134 to boost antioxidant properties or if the ascorbyl glucoside will make the EUK134 less effective. I can't find this information anywhere! Thanks in advance ✨

I'm a little confuced since EUK 134 0.1% conflicts with direct Vit. C but not so much with Vit C derivatives. Resveratrol 3% + Ferulic Acid 3% doesn't seem to conflict with any type of Vit C. Information on the products says water can impair the stability of any antioxidant, I'm guessing that's why both the antioxidant serums are anhydrous. The ascorbyl glucoside solution 12% on the other hand is water-based, that's why I'm not sure if it's alright to mix the products for more antioxidant properties or just layer them. If I layer them, I should use waterbased Vit C before the anhydrous antioxidant serum right?

I'm sorry if my post is a little confusing. I'm confused as well lol.

Hi, can I use this serum of vitamin c on summer time? Thanks