A linked dicarboxylate phaseβtransfer catalyst enables smooth asymmetric dearomative fluorination of 2βnaphthols with Selectfluor under mild conditions to give the corresponding 1βfluoronaphthalenone derivatives in a highly enantioselective manner. This reaction, which is compatible with various functional groups, is the first example of catalytic asymmetric fluorination of 2βnaphthols, and is expected to be useful in the synthesis of bioactive molecules.
https://ift.tt/3dOVIGf
Link:
http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rb088.pub2/abstract
Koichi Mikami1, Yukihiro Motoyama1, Jean Michel Brunel2
Published Online: 15 APR 2006
DOI: 10.1002/047084289X.rb088.pub2
I basically just need to know the procedure for the step labelled (2) in the abstract - so the supporting information would also be very much appreciated!
I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.
Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.
Do your worst!
I'm surprised it hasn't decade.
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies π
It really does, I swear!
Buenosdillas
Theyβre on standbi
Pilot on me!!
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
When I got home, they were still there.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
Nothing, he was gladiator.
I won't be doing that today!
[Removed]
You take away their little brooms
This morning, my 4 year old daughter.
Daughter: I'm hungry
Me: nerves building, smile widening
Me: Hi hungry, I'm dad.
She had no idea what was going on but I finally did it.
Thank you all for listening.
There hasn't been a post all year!
Why
Itβs pronounced βNoel.β
After all his first name is No-vac
What, then, is Chinese rap?
Edit:
Notable mentions from the comments:
-
Spanish/Swedish/Swiss/Serbian hits
-
French/Finnish art
-
Country/Canadian rap
-
Chinese/Country/Canadian rock
-
Turkish/Tunisian/Taiwanese rap
There hasn't been a single post this year!
(Happy 2022 from New Zealand)
Nothing, it just waved
Him: I can explain everything!
(It's his best joke yet I think)
Not just a phase : A dianionic phaseβtransfer catalyst enables fluorinative dearomatization of 2βnaphthols with Selectfluor to afford the fluorinated naphthalenone derivatives in good yield and with high enantioselectivity. This reaction, which is compatible with a range of functional groups, is the first example of catalytic asymmetric fluorination of 2βnaphthols.
Abstract
A linked dicarboxylate phaseβtransfer catalyst enables smooth asymmetric dearomative fluorination of 2βnaphthols with Selectfluor under mild conditions to give the corresponding 1βfluoronaphthalenone derivatives in a highly enantioselective manner. This reaction, which is compatible with a range of functional groups, is the first example of catalytic asymmetric fluorination of 2βnaphthols, and is expected to be useful in the synthesis of bioactive molecules.
https://ift.tt/3dOVIGf
